ZipRecruiter

Log In

1

Regulatory Director Jobs (NOW HIRING)

Calico

Director, Regulatory Affairs

South San Francisco, CA · On-site

$275K - $280K/yr

Calico is seeking a Regulatory Director that will be responsible for, in collaboration with development partners as applicable, developing and implementing innovative regulatory strategies to support ...

U.S. Bank

Financial and Regulatory Director

Edison, NJ · On-site

$139K - $163K/yr

At U.S. Bank, we're on a journey to do our best. Helping the customers and businesses we serve to make better and smarter financial decisions and enabling the communities we support to grow and ...

US Bank

Financial and Regulatory Director

Edison, NJ

$139K - $163K/yr

At U.S. Bank, we're on a journey to do our best. Helping the customers and businesses we serve to make better and smarter financial decisions and enabling the communities we support to grow and ...

Hawk Group

Alaska Regulatory Lead

Anchorage, AK · On-site

The Regulatory Director leads and coordinates all regulatory permitting and stakeholder engagement activities for the Client project in Alaska. This role works with the engineering team to meet all ...

The Gowan Co.

Global Regulatory Asset Lead

Yuma, AZ · On-site

Global Regulatory Director Key Responsibilities * Leadership and Team Management: The role will involve either a direct or indirect line in managing a team of Regulatory Managers assigned to ...

MBX Biosciences

Director, Regulatory

Boston, MA · Hybrid

$163K - $215K/yr

Position Summary The Director of Regulatory Affairs at MBX Biosciences will lead and execute global regulatory strategies that support the development and approval of MBX's clinical stage and early ...

Kinder Morgan

Director - Regulatory

Houston, TX · On-site

$143K - $189K/yr

Minimum 15 years direct work experience with regulatory matters, specifically certificate applications, in a natural gas industry environment is preferred. * Familiarity with agencies including the ...

Dana-Farber Cancer Institute

The Regulatory Compliance Director is a key part of the Compliance team, collaborating across all areas of the organization with a focus on creating a culture of trust and ethical conduct and ...

next page

Showing results 1-20

All JobsRegulatory Director Jobs

Regulatory Director information

See salary details

$91K

$176.2K

$248.5K

How much do regulatory director jobs pay per year?

As of Jun 27, 2026, the average yearly pay for regulatory director in the United States is $176,150.00, according to ZipRecruiter salary data. Most workers in this role earn between $150,000.00 and $198,000.00 per year, depending on experience, location, and employer.

What is the difference between Regulatory Director vs Regulatory Manager?

AspectRegulatory DirectorRegulatory Manager
ResponsibilitiesOversees regulatory strategies, compliance policies, and interacts with senior leadershipManages daily regulatory activities, ensures compliance, and implements policies
Required CredentialsTypically requires advanced degrees and extensive regulatory experienceRequires relevant certifications and several years of experience
Work EnvironmentStrategic, leadership-focused, often in corporate or global settingsOperational, team-oriented, often in specific departments or regions

The Regulatory Director focuses on strategic oversight and high-level compliance initiatives, while the Regulatory Manager handles daily regulatory operations and team management. Both roles require regulatory knowledge, but the director position involves broader leadership responsibilities.

How does a Regulatory Director typically collaborate with cross-functional teams to ensure compliance across the organization?

A Regulatory Director works closely with departments such as legal, quality assurance, research and development, and marketing to interpret and apply relevant regulations throughout the product lifecycle. They lead or participate in cross-functional meetings to provide regulatory guidance, address compliance risks, and help teams prepare for audits or submissions. This collaboration ensures that all departments are aligned with regulatory standards, minimizing risks and supporting smooth market access. Effective communication and negotiation skills are essential, as the Regulatory Director often acts as a bridge between technical teams and regulatory agencies.

What is a Regulatory Director?

A Regulatory Director is a senior professional responsible for overseeing and managing a company's compliance with regulations and laws relevant to its industry. They develop regulatory strategies, ensure products and processes meet legal standards, and often interact with government agencies. Their role is critical in industries like pharmaceuticals, finance, and healthcare, where regulations are complex and constantly evolving. Regulatory Directors also guide teams, provide regulatory advice during product development, and help minimize business risks associated with non-compliance.

What are the key skills and qualifications needed to thrive as a Regulatory Director, and why are they important?

To thrive as a Regulatory Director, you need deep expertise in regulatory affairs, compliance frameworks, and industry-specific regulations, typically supported by an advanced degree in law, science, or a related field. Familiarity with regulatory submission systems, document management tools, and certifications such as RAC (Regulatory Affairs Certification) are highly valued. Strong leadership, strategic thinking, and effective communication enable you to navigate complex regulations and lead cross-functional teams. These skills ensure timely product approvals, mitigate compliance risks, and support organizational growth in highly regulated industries.
More about Regulatory Director jobs
What cities are hiring for Regulatory Director jobs? Cities with the most Regulatory Director job openings:
What are the most commonly searched types of Regulatory jobs? The most popular types of Regulatory jobs are:
What states have the most Regulatory Director jobs? States with the most job openings for Regulatory Director jobs include:
Regulatory Director jobs near you
Infographic showing various Regulatory Director job openings in the United States as of June 2026, with employment types broken down into 1% As Needed, 84% Full Time, 12% Part Time, 1% Temporary, and 2% Contract. Highlights an 91% Physical, 3% Hybrid, and 6% Remote job distribution, with an average salary of $176,150 per year, or $84.7 per hour.

Director, Regulatory Affairs

Calico

South San Francisco, CA • On-site

$275K - $280K/yr

Full-time

Posted 5 days ago

Job description

Who We Are:
Calico (Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging. Calico will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Calico's highly innovative technology labs, its commitment to curiosity-driven discovery science, and, with academic and industry partners, its vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs.
Position Description:
Calico is seeking a Regulatory Director that will be responsible for, in collaboration with development partners as applicable, developing and implementing innovative regulatory strategies to support development programs, in compliance with health authority guidelines and regulations. The successful candidate should be able to collaborate effectively with cross-functional representatives, collaboration partners, external vendors, and stakeholders, while maintaining a positive team environment.
Position Responsibilities:
  • Accountable to develop and execute the world-wide regulatory strategy for assigned programs (from IND-enabling to clinical proof-of-concept and beyond), which may include programs that are first-in-class, where no or limited FDA guidance exists, that have an external business partner, and where there are multiple indications
  • Provide high-level regulatory counsel to Executive Leadership, Clinical Development, CMC, and Commercial teams regarding clinical trial designs, surrogate endpoints, accelerated approval strategies, and risk mitigation
  • Lead interactions with global health agencies to inform global regulatory/ registration requirements for assigned programs, developing briefing packages for such engagements
  • Collaborate with the executive team to define regulatory strategies consistent with Calico's mission for both internal and partnership programs
  • Oversee or directly enable the compilation, review, and submission of regulatory applications and submissions to agencies, ensuring accuracy, completeness, and timeliness
  • Collaborate with CMC, CMC Regulatory, and other stakeholders to develop effective CMC regulatory strategies
  • Represent Regulatory Affairs on development teams and support development teams in interpreting and applying regulations and guidance documents
  • Offer strategic and regulatory compliance input to protocols, reports, and other source documents
  • Stay updated on global regulatory guidance and regulations, communicating key updates to senior leadership and project teams, anticipating changes in the regulatory landscape, and developing proactive strategies accordingly
  • Collaborate with cross-functional teams and support functions, including full-time staff and independent consultants, as required
  • Other duties as assigned

Position Requirements:
  • Master's degree in a life science discipline from an accredited college or university; PhD preferred
  • Minimum of 10 years of regulatory affairs experience in an industry, academia, or clinical research organization setting, with experience with rare disease development and/or novel endpoints preferred
  • Proven track record of developing and executing regulatory submissions in the biotechnology sector, including experience with at least one major application and approval, preferred (NDA, BLA, MAA, etc.)
  • Direct experience authoring and managing (or oversight of others) substantial regulatory submissions (INDs/CTAs required; experience with successful NDA/BLA/MAA filings is highly desirable)
  • Strong knowledge of global regulations, including, but not limited to, FDA and EMA
  • Experience with mechanisms to expedite agency interactions
  • Advanced skill in creating and assessing proposals to regulatory authorities on regulatory paths and clinical plans, guiding development teams with recommendations for changes/refinements based on ongoing regulatory outcomes throughout development, and in leading productive health authority interactions, including well organized preparation of cross functional teams
  • Excellent communication skills with the ability to influence stakeholders internally and externally
  • Self-motivated, with the ability to work independently or as part of a team
  • Strategic thinker with strong problem-solving skills
  • Exceptional organizational skills with the ability to prioritize tasks in a fast-paced environment
  • Self-motivated and able to work collaboratively
  • Ability to "roll up sleeves" in a start-up environment and a positive can-do attitude
  • Must be willing to work onsite at least four days per week

The estimated base salary range for this role is $275,000 - $280,000. Actual pay will be based on a number of factors including experience and qualifications. This position is also eligible for two annual cash bonuses.

Apply