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Postdoctoral Position In Peptide Synthesis Jobs (NOW HIRING)

Post Doctoral Appointee

Bloomington, IN ยท On-site

$45K - $61K/yr

... Position Title: Postdoctoral Fellow in Peptide Chemistry and Cancer Immunotherapy The Peptide ... Synthesize therapeutic peptide vaccine candidates using Fmoc solid-phase peptide synthesis (SPPS)

POSITION TITLE: Research Scientist POSITION SUMMARY: We are seeking an experienced and highly ... D and/or postdoc in chemical or biological sciences with a strong focus on peptide chemistry is ...

Synthetic Chemist II

Pasadena, CA ยท On-site

$38 - $42/hr

Synthetic Chemist II Position Title: Analyst II Division: Consumer Products Services Entity ... Design, validate and implement synthesis projects in organic synthesis, peptide synthesis ...

$38 - $42/hr

Synthetic Chemist II Position Title: Analyst II Division: Consumer Products Services Entity ... Design, validate and implement synthesis projects in organic synthesis, peptide synthesis ...

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How much do postdoctoral position in peptide synthesis jobs pay per year?

As of Sep 7, 2026, the average yearly pay for postdoctoral position in peptide synthesis in the United States is $85,959.00, according to ZipRecruiter salary data. Most workers in this role earn between $56,000.00 and $116,000.00 per year, depending on experience, location, and employer.

What is a postdoctoral position in peptide synthesis?

A Postdoctoral Position in Peptide Synthesis is a research-focused role for individuals who have recently completed their Ph.D. in chemistry, biochemistry, or a related field. The primary responsibility is to design, synthesize, and characterize peptides for various scientific studies, often in drug discovery or biomedical research. Postdocs in this area may also be involved in developing new synthetic methodologies, analyzing experimental data, and publishing their findings. These roles typically provide training and experience necessary for an academic or industry career in chemical and biological sciences.

What are the key skills and qualifications needed to thrive in a postdoctoral position in peptide synthesis?

To thrive in a Postdoctoral Position in Peptide Synthesis, you need a PhD in chemistry, biochemistry, or a related field with a solid background in peptide synthesis and purification techniques. Experience with analytical tools such as HPLC, mass spectrometry, and peptide synthesizers, as well as familiarity with relevant software, is typically required. Strong problem-solving abilities, attention to detail, and effective collaboration and communication skills help you excel in multidisciplinary research environments. These skills ensure the successful design, synthesis, and analysis of peptides, contributing to impactful research outcomes.

What are some common challenges faced in a postdoctoral position in peptide synthesis, and how can they be addressed?

Postdoctoral researchers in peptide synthesis often encounter challenges such as optimizing synthetic routes for complex peptides, managing the purification of difficult sequences, and troubleshooting low yields or unexpected side reactions. These hurdles can be addressed by staying current with the latest literature, using advanced purification techniques like HPLC, and collaborating closely with other chemists or biochemists in the lab. Open communication with mentors and team members also helps in brainstorming solutions and sharing best practices, fostering a collaborative environment that is essential for overcoming technical obstacles.
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Infographic showing various Postdoctoral Position In Peptide Synthesis job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 78% Full Time, 17% Part Time, 1% Temporary, and 3% Contract. Highlights an 91% Physical, 2% Hybrid, and 7% Remote job distribution, with an average salary of $85,959 per year, or $41.3 per hour.

Position Title: Postdoctoral Fellow in Peptide Chemistry and Cancer Immunotherapy The Peptide Lab...

Indiana University Academic Positions

Kokomo, IN โ€ข On-site

$42K - $58K/yr

Full-time

Posted 4 days ago


Job description

Position Details
Title Post Doctoral Appointee Specific Title Appointment Type Postdoctoral Fellow Department IUSM - Microbiology & Immunology Campus IU School of Medicine Indianapolis Position Summary
Position Title: Postdoctoral Fellow in Peptide Chemistry and Cancer Immunotherapy
The Peptide Laboratory at the Indiana University School of Medicine is seeking an outstanding and highly motivated Postdoctoral Fellow to join a multidisciplinary research program focused on the discovery and translation of next-generation peptide-based cancer immunotherapies.
The laboratory has pioneered B-cell epitope peptide vaccines targeting immune checkpoint molecules and oncogenic growth factor receptors and is advancing novel multivalent and multispecific vaccine platforms toward clinical translation. The successful candidate will lead innovative projects integrating peptide chemistry, structural immunology, cancer biology, and translational immunotherapy.
This position offers the opportunity to work in a highly collaborative environment with access to state-of-the-art chemistry, proteomics, immunology, and animal research cores while contributing to projects with strong publication, patent, and clinical translation potential.
Research Focus
Current research programs include:
  • Therapeutic peptide vaccines targeting PD-1, CTLA-4, TIGIT, IL1RAP, HER-2/HER-3, VEGF, and other immune and tumor-associated targets
  • Development of multispecific and multivalent peptide vaccine platforms
  • Peptide conjugation using click chemistry and advanced linker technologies
  • Structural design and optimization of conformational B-cell epitopes
  • Combination immunotherapy with chemotherapy, targeted therapies, and immune checkpoint modulation
  • Translation of peptide vaccines from preclinical models to Phase I clinical trials
Responsibilities
The successful candidate will:
  • Synthesize therapeutic peptide vaccine candidates using Fmoc solid-phase peptide synthesis (SPPS).
  • Develop and optimize peptide conjugation strategies, including CuAAC, SPAAC, thiol-maleimide coupling, PEGylation, and multivalent scaffold assembly.
  • Purify and characterize peptides using analytical and preparative HPLC, LC-MS, and MALDI-TOF mass spectrometry.
  • Execute studies evaluating vaccine immunogenicity and antitumor efficacy in preclinical models.
  • Collaborate with multidisciplinary teams in chemistry, immunology, oncology, and bioinformatics.
  • Analyze and interpret experimental data and maintain detailed laboratory records.
  • Prepare manuscripts for publication in high-impact journals.
  • Contribute to NIH grant applications, progress reports, and intellectual property development.
  • Mentor graduate students, technicians, and undergraduate trainees.
  • Present research findings at national and international scientific meetings.

IU School of Medicine is committed to being a welcoming campus community and we seek candidates whose research, teaching, and community engagement efforts contribute to robust learning and working environments for all students, staff, and faculty. We invite individuals who will join us in our mission to improve health equity and well-being for all throughout the state of Indiana.

Indianapolis is the capital and most populous city in the State of Indiana. It is growing economically thanks to a strong corporate base anchored by the life sciences. Indiana is home to one of the nation's largest concentrations of health sciences companies. Indianapolis has a sophisticated blend of charm and culture with a wonderful balance of business and leisure. The growing residential base is supported by rich amenities and quality of life - the city possesses a variety of professional sports, arts venues, and outdoor recreation areas. Residents of this dynamic city and surrounding suburbs enjoy leading educational systems and top-ranked universities paired with a diverse population. Indianapolis International Airport is a top-ranked international airport that has been named "Best Airport in North America" by Airports Council International for many years. For additional information on life in
Indy: https://faculty.medicine.iu.edu/relocation
Faculty Affairs and Professional Development | IU School of Medicine



Basic Qualifications
Required Qualifications
  • Ph.D. in Chemistry, Medicinal Chemistry, Chemical Biology, Biochemistry, Pharmaceutical Sciences, Immunology, or a closely related field.
  • Demonstrated expertise in peptide synthesis and purification.
  • Strong publication record in peer-reviewed scientific journals.
  • Experience designing and troubleshooting independent research projects.
  • Excellent written and oral communication skills.
  • Ability to work independently while contributing effectively to collaborative research.
Preferred Qualifications
Preference will be given to candidates with expertise in one or more of the following:
  • Automated and manual Fmoc solid-phase peptide synthesis
  • Peptide cyclization and constrained peptide design
  • Click chemistry (CuAAC and SPAAC)
  • Bioconjugation chemistry and linker design
  • Reverse-phase HPLC method development
  • LC-MS and MALDI-TOF characterization
  • Cancer immunology
  • Tumor immunology
  • Vaccine development
  • Immune checkpoint biology
  • Mouse models of cancer
  • Flow cytometry
  • ELISA and antibody characterization
Cell culture and molecular biology techniques
Department Contact for Questions
Gerri Herron
HR Coordinator
geherron@iu.edu
Additional Qualifications Special Instructions Priority Application Review Deadline Expected Start Date 11/02/2026 Posting Number IUSM-02499-2026