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Overnight Rn Jobs in Charleston, SC (NOW HIRING)

Gentiva

Registered Nurse On Call

North Charleston, SC · On-site

As an After Hours Hospice RN, you'll respond to patient needs during evenings, nights, weekends ... overnight nursing roles • Strong documentation and electronic medical records (EMR) skills We ...

Commonwise Home Care

CNA Caregiver

Charleston, SC · On-site

$16 - $20/hr

... evening, or overnight) - we believe in empowering you to create a schedule that works for you ... Mentorship from RN Care Managers * On-site support and training from Caregiver Ambassadors & RNs * ...

Commonwise Home Care

CNA Caregiver

Charleston, SC

$17 - $19/hr

... evening, or overnight) - we believe in empowering you to create a schedule that works for you ... Mentorship from RN Care Managers * On-site support and training from Caregiver Ambassadors & RNs * ...

Commonwise Home Care

CNA Caregiver

Charleston, SC · On-site

$17 - $19/hr

... evening, or overnight) -- we believe in empowering you to create a schedule that works for you ... Mentorship from RN Care Managers * On-site support and training from Caregiver Ambassadors & RNs * ...

Care Team Solutions

Travel RRT Pediatrics

Charleston, SC · On-site

$2.0K/wk

Travel Registered Nurse must have 2+ years of recent experience in particular specialty Details ... Shift: 12 Hours Overnight shift. * Hours Per Week: 36 Hours * Employment Type: Contract * Gross ...

Care Team Solutions

Travel RRT Pediatrics

Charleston, SC · On-site

$2.0K/wk

Travel Registered Nurse must have 2+ years of recent experience in particular specialty Details ... Shift: 12 Hours Overnight shift. * Hours Per Week: 36 Hours * Employment Type: Contract * Gross ...

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Overnight Rn information

See Charleston, SC salary details

$22

$53

$103

How much do overnight rn jobs pay per hour?

As of Sep 3, 2026, the average hourly pay for overnight rn in Charleston, SC is $53.55, according to ZipRecruiter salary data. Most workers in this role earn between $36.01 and $60.29 per hour, depending on experience, location, and employer.

What is an overnight RN?

Overnight Registered Nurses (RNs) are licensed nursing professionals who work night shifts in healthcare settings such as hospitals, nursing homes, or clinics. Their responsibilities include monitoring patient health, administering medications, responding to emergencies, and collaborating with other staff to provide continuous care during overnight hours. Working overnight requires strong attention to detail, adaptability, and the ability to work independently. These nurses play a critical role in ensuring patient safety and care throughout the night when staffing is often reduced.

What are the key skills and qualifications needed to thrive as an overnight RN?

To thrive as an Overnight RN, you need a solid background in clinical nursing, acute care skills, and an active RN license, often accompanied by experience in night shift or critical care environments. Familiarity with electronic health records (EHR), medication administration systems, and bedside monitoring technology is essential. Strong organization, resilience, and effective communication are vital soft skills for handling high-pressure situations and working with patients and limited overnight staff. These competencies ensure safe, high-quality patient care and efficient operations during overnight hours when resources and support may be reduced.

What unique challenges do overnight RNs face compared to day-shift nurses?

Overnight RNs often encounter unique challenges such as managing fatigue and adapting to disrupted sleep patterns, which can impact alertness and decision-making. They typically work with reduced staffing levels and fewer support resources, requiring a higher degree of autonomy and strong critical thinking skills. Additionally, overnight RNs may perform more independent assessments and handle emergencies until daytime teams arrive, making adaptability and effective communication with both patients and incoming staff essential.

What are the most commonly searched types of Rn jobs in Charleston, SC?

The most popular types of Rn jobs in Charleston, SC are:

What cities near Charleston, SC are hiring for Overnight Rn jobs?

Cities near Charleston, SC with the most Overnight Rn job openings:

Overnight Rn jobs near you
Infographic showing various Overnight Rn job openings in Charleston, SC as of August 2026, with employment types broken down into 3% As Needed, 53% Full Time, 15% Part Time, and 29% Contract. Highlights an 99% Physical, and 1% Remote job distribution, with an average salary of $111,390 per year, or $53.6 per hour.

CRNA - Anesthesiology job available in Charleston, South Carolina

Lancesoft INC

Charleston, SC

Temporary

Re-posted 14 days ago

Job description

Position: CRNA (Certified Registered Nurse Anesthetist)
Assignment: Locum Tenens
Location: Charleston, South Carolina
Duration: Minimum 3 months with option to extend
Start Date: ASAP
Schedule: 13-hour shifts | Daytime & Evening Coverage

We are seeking experienced CRNAs for a locum tenens opportunity providing medically directed anesthesia services in a large academic hospital setting. The assignment offers guaranteed 13-hour shifts with coverage across a broad range of surgical specialties.

Job Responsibilities
  • Provide medically directed anesthesia care.
  • Manage approximately 3–5 cases per day.
  • Provide general anesthesia services across multiple specialties.
  • Case mix includes:
    • General Anesthesia
    • Neuro & Spine
    • Orthopedics
    • ENT
    • GYN
    • Urology
    • Oncology
  • Provide coverage in operating rooms and select non-operating room locations.
  • Non-operating room sites may include:
    • CT
    • MRI
    • Bronchoscopy
    • Neuro-Angio
    • Interventional Radiology
  • Work primarily at the main hospital.
  • Flexibility to work at nearby outpatient/ambulatory locations as scheduling needs require.
  • Collaborate with an established anesthesia team of approximately 42 CRNAs.
Qualifications
  • Minimum 3 years of CRNA experience required.
  • Active South Carolina license or license well in process.
  • Must be proficient in Epic EMR.
  • Prior locum/travel experience preferred.
  • Must be flexible to work at the main hospital and nearby alternate locations as needed.
  • Candidates must meet the required locum radius criteria.
  • Academic medical center experience is not required.
  • No OB, cardiac, or regional block experience required.
Working Hours

Shift Options:

  • 6:00 AM–7:30 PM
  • 8:00 AM–9:30 PM
  • 13-hour shifts are guaranteed.
  • 0.5-hour unpaid lunch.
  • Schedule includes some weekend shifts.
  • No overnight call required.
Skills
  • General Anesthesia
  • Medically Directed Anesthesia
  • Neuro & Spine
  • Orthopedic Anesthesia
  • ENT
  • GYN/Urology
  • Oncology
  • Robotics
  • Trauma & Surgical Cases
  • Non-Operating Room Anesthesia
  • Interventional Radiology
  • Epic EMR

Interested in learning more? Contact us today for additional details and apply now!

LanceSoft logo

About LanceSoft

Sourced by ZipRecruiter

Established in 2000, LanceSoft is a Certified MBE and Woman-Owned organization. Lancesoft Inc. is one of the highest rated companies in the industry. We have been recognized as one of the Largest Staffing firms and ranked in the top 50 fastest Growing Healthcare Staffing firms in 2022. Lancesoft offers short- and long-term contracts, permanent placements, and travel opportunities to credentialed and experienced professionals throughout the United States. We pride ourselves on having industry leading benefits. We understand the importance of partnering with an expert who values your needs, which is why we're 100% committed to finding you an assignment that best matches your career and lifestyle goals. Our team of experienced career specialists takes the time to understand your needs and match you with the right job Lancesoft has been chosen by Staffing Industry Analysts as one of the Best Staffing Firms to Work for.LanceSoft specializes in providing Registered Nurses, Nurse Practitioners, LPNs/LVNs, Social Workers, Medical Assistants, and Certified Nursing Assistants to work in Acute Care Centers, Skilled Nursing Facilities, Long-Term Care centers, Rehab Facilities, Behavioral Health Centers, Drug & Alcohol Facilities, Home Health & Community Health, Urgent Care Clinics, and many other provider-based facilities.

Industry

Recruiting and staffing services

Company size

1,001 - 5,000 Employees

Headquarters location

Herndon, VA, US

Year founded

2000

Social media

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