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Mass Spectrometry Jobs (NOW HIRING)

Eagle

Project Chemist (Mass Spectrometry)

Houston, TX · On-site

Experience with mass spectrometry-based protein and peptide characterization, including sample preparation, instrument operation, and data analysis, preferred * Experience with LC-MS/MS quantitation ...

IQVIA LLC

NY · On-site

$83 - $173/hr

We are seeking Associate Principal Scientist, Liquid Chromatography-Mass Spectrometry (LCMS) Assay Development to join IQVIA Laboratories at Ithaca, NY. We hire passionate innovators who drive health ...

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Eagle

Project Chemist (Mass Spectrometry)

Houston, TX · On-site

Experience with mass spectrometry-based protein and peptide characterization, including sample preparation, instrument operation, and data analysis, preferred * Experience with LC-MS/MS quantitation ...

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How much do mass spectrometry jobs pay per hour?

As of Aug 13, 2026, the average hourly pay for mass spectrometry in the United States is $22.62, according to ZipRecruiter salary data. Most workers in this role earn between $18.51 and $24.04 per hour, depending on experience, location, and employer.

What is mass spectrometry?

A Mass Spectrometry job involves using mass spectrometers to analyze the composition of chemical or biological samples. Professionals in this field work in industries such as pharmaceuticals, environmental science, forensics, and biotechnology. Their responsibilities include sample preparation, instrument calibration, data interpretation, and reporting findings. These roles require expertise in analytical chemistry, laboratory techniques, and data analysis software.

What are the key skills and qualifications needed for mass spectrometry?

To thrive in Mass Spectrometry, you need a strong background in analytical chemistry or biochemistry, experience operating mass spectrometry instruments, and a relevant degree such as a B.Sc., M.Sc., or Ph.D. in a related field. Familiarity with laboratory information management systems (LIMS), chromatography software, and certifications such as ASMS or relevant lab safety training is also highly valued. Attention to detail, problem-solving ability, and effective communication skills distinguish top performers. These skills ensure accurate data generation, effective troubleshooting, and smooth collaboration with research teams or clients.

What does a mass spectrometry professional do?

Professionals working in Mass Spectrometry are responsible for preparing and analyzing samples, calibrating and maintaining instruments, and interpreting complex analytical data. They often work closely with other scientists, research associates, or quality control teams to support research, development, or quality assurance projects. Documenting procedures and results accurately is crucial, as is troubleshooting equipment or methodology when challenges arise. Additionally, they may participate in method development or validation, contributing to process optimization and innovation within their organization.

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Mass Spectrometry jobs near you
Infographic showing various Mass Spectrometry job openings in the United States as of August 2026, with employment types broken down into 70% Full Time, 29% Part Time, and 1% Contract. Highlights an 94% Physical, 3% Hybrid, and 3% Remote job distribution, with an average salary of $47,050 per year, or $22.6 per hour.

Project Chemist (Mass Spectrometry)

Eagle

Houston, TX • On-site

Full-time

Re-posted 4 days ago

Job description

What We Are Looking For

We are seeking a motivated Project Chemist to support routine LC-MS–based analysis in a fast-paced laboratory environment. This role is responsible for the timely and reliable execution of LC-MS/MS workflows, including sample preparation, instrument operation, troubleshooting, and data review. The ideal candidate is comfortable working with minimal supervision, maintaining instrument performance, and delivering high-quality analytical results in a timely manner.

What You Will Do

  • Perform routine LC-MS based assays including peptide mapping, intact mass analysis and protein/small molecule quantitation in a timely and compliant manner
  • Prepare samples, standards, mobile phases, buffers, and other laboratory solutions
  • Operate and maintain LC-MS/MS and HPLC/UHPLC systems following SOPs
  • Conduct routine analytical runs and monitor instrument performance
  • Review, organize, interpret, and document analytical data and laboratory records
  • Identify and report unexpected test results, providing initial troubleshooting where applicable.
  • Perform system suitability, calibration, and QC checks
  • Troubleshoot basic instrument and method issues
  • Maintain laboratory cleanliness, inventory, and organization
  • Support method optimization and validation activities as appropriate
  • Collaborate with cross-functional team members to support project timelines and deliverables

Who You Are

  • Bachelor’s or Master’s degree in chemistry, Analytical Chemistry, Biochemistry, or related field
  • Hands-on experience with LC-MS/MS instrumentation and workflows
  • Experience with mass spectrometry–based protein and peptide characterization, including sample preparation, instrument operation, and data analysis, preferred
  • Experience with LC-MS/MS quantitation using MRM and/or SIR acquisition modes preferred
  • Hands-on experience with HPLC or UHPLC systems
  • Familiarity with biological and/or chemical sample matrices
  • Experience with basic wet chemistry and sample preparation techniques
  • Familiarity with GMP (Good Manufacturing Practices) and applicable regulatory requirements (e.g., FDA, ICH)
  • Strong attention to detail, organizational skills, and documentation practices
  • Comfortable working with laboratory software and data management systems
  • Ability to work independently as well as collaboratively in a team environment
  • Strong verbal and written communication skills

Preferred Experience

  • Hands-on experience with HPLC, UPLC, and MS instrumentation.
  • Knowledge of peptide synthesis and purification techniques.
  • Experience in a pharmaceutical or biotechnology setting.
  • Understanding of protein chemistry and post-translational modifications.

Who We Are

Serving customers since 2004, Eagle offers the highest quality in preparation testing for sterility, bacterial endotoxins, microbial detection, beyond-use dating (BUD) determination and active ingredient potency. State-of-the-art equipment, combined with the experience and knowledge of our team, makes Eagle the best choice for all testing needs. The Eagle team is committed not only to performing the best quality control testing but also working relentlessly with our customers on solutions if tests receive unexpected results. Learn more at www.eagleanalytical.com. 

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