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Locum Rn Jobs in Greenville, SC (NOW HIRING)

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Locum Rn information

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$12

$57

$174

How much do locum rn jobs pay per hour?

As of Aug 21, 2026, the average hourly pay for locum rn in Greenville, SC is $57.48, according to ZipRecruiter salary data. Most workers in this role earn between $31.90 and $66.89 per hour, depending on experience, location, and employer.

What is a Locum RN?

A Locum RN, or Locum Registered Nurse, is a qualified nurse who temporarily fills staffing gaps in healthcare facilities, such as hospitals, clinics, or nursing homes. They may cover for permanent staff members who are on leave, or help during periods of increased patient demand. Locum RNs perform all the standard duties of a registered nurse, including patient care, administering medications, and collaborating with healthcare teams. This type of work offers flexibility and the opportunity to gain experience in different clinical environments.

What are the key skills and qualifications needed to thrive as a Locum RN?

To thrive as a Locum Registered Nurse (RN), you need a current RN license, a solid background in clinical care, and experience adapting quickly to new healthcare environments. Familiarity with various electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are typically required. Strong communication, adaptability, and problem-solving skills help locum RNs integrate smoothly into diverse teams and deliver quality patient care. These competencies are crucial for providing consistent, high-quality nursing support across different facilities and ensuring patient safety during temporary assignments.

What are some common challenges faced by Locum RNs when adapting to new clinical settings?

Locum RNs often encounter unique challenges when integrating into unfamiliar healthcare environments, such as quickly learning new protocols, adapting to different electronic health record systems, and building rapport with established teams. Flexibility and strong communication skills are essential, as locum nurses must efficiently assess patient needs while adhering to facility-specific procedures. Despite these challenges, many locum RNs find the variety and exposure to diverse practices rewarding, and these experiences can strengthen their clinical versatility.

What is the difference between Locum Rn vs Staff Rn?

AspectLocum RnStaff Rn
CredentialsRegistered Nurse license, possibly specialized certificationsRegistered Nurse license, possibly specialized certifications
Work EnvironmentTemporary assignments in various healthcare settingsFull-time or part-time employment in a specific healthcare facility
Employer UsageStaffing agencies, hospitals, clinicsHospitals, clinics, healthcare facilities
Search IntentTemporary nursing jobs, short-term assignmentsPermanent or long-term nursing positions

In summary, a Locum Rn is a temporary nurse filling short-term staffing needs, often through agencies, while a Staff Rn is a full-time or part-time employee working consistently at a healthcare facility. Both roles require valid RN licensure and similar certifications, but their employment types and work environments differ significantly.

What are the most commonly searched types of Rn jobs in Greenville, SC?

The most popular types of Rn jobs in Greenville, SC are:

What are popular job titles related to Locum Rn jobs in Greenville, SC?

For Locum Rn jobs in Greenville, SC, the most frequently searched job titles are:

What job categories do people searching Locum Rn jobs in Greenville, SC look for?

The top searched job categories for Locum Rn jobs in Greenville, SC are:

What cities near Greenville, SC are hiring for Locum Rn jobs?

Cities near Greenville, SC with the most Locum Rn job openings:

Infographic showing various Locum Rn job openings in Greenville, SC as of August 2026, with employment types broken down into 3% As Needed, 59% Full Time, 16% Part Time, and 22% Contract. Highlights an 99% Physical, and 1% Remote job distribution, with an average salary of $119,550 per year, or $57.5 per hour.

Hematology/Oncology Physician

Ascend Medical Staffing

Greenville, SC • On-site

Full-time

Re-posted 5 days ago


Job description

Bon Secours St. Francis Downtown is looking for locum coverage in Medical Oncology-SC/IMLC license required-$450 Hr-Asap Start
JOB DETAILS:
Practice Setting: Free-Standing Cancer Center
Reason for Coverage: Loss of provider
Call Schedule: No call during locum period; call expected if placed perm; call schedule is 1 week out of every 6-8 weeks
Call Ratio: No call during locum period; call expected if placed perm; call schedule is
1 week out of every 6-8 weeks
Patient Population for Required Coverage: Adult, Geriatric
What Percentage of the Practice is Hematology %, Oncology %, Internal Medicine %: 65% benign hematology, 35% malignant oncology, 0% internal medicine
Number of Physicians in Practice: 7
How Many APPs Provide Coverage: 6
Average Number of Patients Per Day - OUTPATIENT: 25
Average Number of Patients Per Day - HOSPITAL (Call/Rounding): 20
Clinical Area: Oncology - Outpatient Setting, Oncology - Inpatient Setting
Trauma Level/Designation (Hospital): N/A
Documentation System/EMR: EPIC
Required Duties: Participation on a Tumor Board, Mgmt. of Bone Marrow Transplants, Blood Bank, Orders Tests, Orders Images, Prescribes
Administration of Chemotherapy: Nurse Oncologist
Estimated Credentialing Timeframe: 60 Days
Facility reimbursement for the following costs: Flight, Hotel, Rental Car, Mileage Billed at the IRS Standard Rate
Submission Requirements
Board Certified in Hematology & Oncology - REQUIRED
Active SC license - REQUIRED
BLS & DEA - REQUIRED
Clean background required for Emergency temps - REQUIRED
A Self-Query NPDB report is mandatory at the time of presentation. The Self-Query NPDB report must be dated within 30 days of the presentation date. - REQUIRED
Additional Facility Information
Facility
Bon Secours - St. Francis Downtown
Unit / Floor
Medical Oncology
Address
Greenville, SC 29601
EMR
EPIC
Number of Beds
245
Contact:
Robert Brabbs BSN/RN
Ascend Medical Staffing