ZipRecruiter

Log In

1

Legend Biotech Jobs (NOW HIRING)

Legend Biotech USA, Inc.

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies ...

Legend Biotech USA, Inc.

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies ...

Legend Biotech USA, Inc.

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies ...

Legend Biotech US

Scientist, In Vivo CAR-T

Somerset, NJ · On-site

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies ...

Legend Biotech USA, Inc.

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies ...

Legend Biotech USA, Inc.

$83K - $109K/yr

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies ...

Legend Biotech USA, Inc.

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies ...

Legend Biotech US

Corporate Counsel

Bridgewater, NJ · On-site

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies ...

Legend Biotech USA, Inc.

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies ...

next page

Showing results 1-20

All JobsLegend Biotech Jobs

Legend Biotech information

See salary details

$12

$23

$36

How much do legend biotech jobs pay per hour?

As of Jun 9, 2026, the average hourly pay for legend biotech in the United States is $23.03, according to ZipRecruiter salary data. Most workers in this role earn between $18.75 and $24.28 per hour, depending on experience, location, and employer.

What are the typical career growth opportunities for professionals at Legend Biotech?

Legend Biotech offers a variety of career growth opportunities for employees who demonstrate strong performance and a commitment to innovation. Team members often have pathways to advance into leadership positions, project management roles, or specialized scientific expertise areas, depending on their interests and strengths. The company supports professional development through ongoing training, mentorship, and exposure to new technologies and projects. Employees also benefit from working in a collaborative environment that values cross-functional teamwork and scientific advancement, which can open doors to broader roles within the organization.

What is a Legend Biotech job?

A Legend Biotech job refers to a role within Legend Biotech, a global biotechnology company focused on discovering and developing innovative cell therapies for cancer and other diseases. Employees work in various fields, including research and development, manufacturing, clinical operations, and regulatory affairs. These jobs often involve cutting-edge scientific research, product development, and ensuring compliance with industry standards. Positions may be available for scientists, engineers, technicians, and professionals in corporate functions. Joining Legend Biotech offers an opportunity to contribute to groundbreaking advancements in cell therapy and biopharmaceutical innovation.

What are the key skills and qualifications needed to thrive in the Legend Biotech position, and why are they important?

To excel in a role at Legend Biotech, candidates typically need a strong background in life sciences, biotechnology, or related fields, often with advanced degrees such as a BS, MS, or PhD. Familiarity with laboratory techniques, regulatory compliance (such as GMP, GLP), and experience using data analysis software or specialized lab equipment is highly valuable. Excellent problem-solving, teamwork, and communication skills help candidates collaborate across multidisciplinary teams and adapt in a fast-paced, innovative environment. These competencies are critical for driving cutting-edge biotechnological research and product development while ensuring compliance and quality across projects.

What cities are hiring for Legend Biotech jobs? Cities with the most Legend Biotech job openings:
What states have the most Legend Biotech jobs? States with the most job openings for Legend Biotech jobs include:
What job categories do people searching Legend Biotech jobs look for? The top searched job categories for Legend Biotech jobs are:
Legend Biotech jobs near you

Sr. Principal/Principal Scientist

Legend Biotech US

Somerset, NJ • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 11 days ago

Job description

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.
Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.
Legend Biotech is seeking a Sr. Principal/Principal Scientist as part of the Research & Early Development team based in Somerset, NJ.
Role Overview
Legend Biotech is seeking a highly experienced Senior Principal Scientist / Principal Scientist - Flow Cytometry to provide scientific leadership and hands-on expertise in flow cytometry to support cell and gene therapy programs from IND-enabling studies through early- and late-stage clinical development. This role is critical for ensuring scientific rigor, data quality, and strategic insight across in-house and outsourced flow cytometry activities, including assay development, validation, CRO oversight, and deep data interpretation to support translational, PK/PD, and regulatory decision-making.
Key Responsibilities
Scientific & Technical Leadership
  • Lead the design, development, optimization, qualification, and validation of multicolor and spectral flow cytometry assays supporting IND-enabling animal studies and clinical trials.
  • Provide subject-matter expertise in panel design, antibody and reagent qualification, gating strategies, and data analysis for complex immunophenotyping applications.
  • Conduct deep scientific review and interpretation of flow cytometry datasets to support PK/PD, mechanism-of-action, and translational insights.

CRO & Vendor Oversight
  • Serve as the primary scientific lead for external laboratories and CROs performing flow cytometry assays.
  • Oversee assay transfer, validation, execution, troubleshooting, and data delivery at CROs.
  • Ensure outsourced activities meet Legend quality standards, regulatory expectations, and program timelines.
  • Identify risks related to assay performance, data quality, and operational execution, and implement mitigation strategies.

Regulatory & Compliance
  • Author, review, and approve bioanalytical assay validation reports, study reports, and regulatory documentation.
  • Ensure flow cytometry assays and data packages are inspection-ready and compliant with GxP principles and data integrity requirements.
  • Contribute to bioanalytical sections of IND and other regulatory submissions.

Cross-Functional Collaboration
  • Partner with Clinical, Translational Research, Biomarkers, Nonclinical Safety, and Data Science teams to align assay strategy with program objectives.
  • Provide scientific input to study design, endpoint selection, and interpretation of bioanalytical results.
  • Communicate complex data clearly to multidisciplinary stakeholders.

Operational Excellence & Mentorship
  • Establish and maintain SOPs, best practices, and governance for in-house flow cytometry workflows.
  • Mentor and scientifically guide junior scientists and associates.
  • Evaluate and implement new technologies, platforms, and analytical approaches to enhance capabilities.

Requirements
  • Ph.D. in Immunology, Cell Biology, Molecular Biology, or related discipline with 8+ years (Principal Scientist) or 10+ years (Senior Principal Scientist) of relevant industry experience; or M.S. with 12+ years of experience.
  • Extensive hands-on experience with multicolor and spectral flow cytometry platforms.
  • Demonstrated experience supporting cell therapy and/or gene therapy programs.
  • Strong understanding of bioanalytical method development, validation, and regulatory expectations.
  • Proven ability to lead complex programs, influence cross-functional teams, and provide strategic scientific direction.
  • Experience overseeing CROs and external vendors.
  • Excellent written and verbal communication skills.
  • Experience with CAR-T, in vivo gene delivery, or other advanced cell therapy platforms.
  • Experience contributing to IND-enabling or regulatory filings.
  • Background in translational PK/PD applications of flow cytometry.

#Li-JR1
#Li-Onsite
The base pay range below is what Legend Biotech USA Inc. reasonably expects to offer at the time of posting. Actual compensation may vary based on experience, skills, qualifications, and geographic location. The company reserves the right to modify this range as needed and in accordance with applicable laws.
Other Types of Pay: Performance-based bonus and/or equity is available to employees in eligible roles.
Benefits and Paid Time Off: Medical, dental, and vision insurance as well as a 401(k) retirement plan with a company match that vests fully on day one. We offer eight (8) weeks of paid parental leave after just three (3) months of employment, and a paid time off policy that includes vacation time, personal time, sick time, floating holidays, and eleven (11) company holidays. Additional voluntary benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide voluntary commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs; demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.
Pay Range (Base Pay):
$146,410-$192,164 USD
Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.
EEO Statement
It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.
Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.
For information related to our privacy notice, please review: Legend Biotech Privacy Notice.

Apply