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LCMS Scientist

Spring House, PA · On-site

LCMS Scientist Duration: 8 months contract, extendable up to 24 Months Location: Spring House, PA ... Analyze antibodies using peptide mapping, intact mass analysis, native mass spectrometry, and ...

Shimadzu Scientific Instruments

$96K - $100K/yr

LCMS Sales Specialist I Location: Greater Boston Area Salary: $96,000 - $100,000 per year with $78 ... Established in 1975, Shimadzu Scientific Instruments is one of the largest suppliers of analytical ...

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How much do lcms analyst jobs pay per year?

As of Sep 2, 2026, the average yearly pay for lcms analyst in the United States is $73,261.00, according to ZipRecruiter salary data. Most workers in this role earn between $52,500.00 and $87,000.00 per year, depending on experience, location, and employer.

What does an LCMS analyst do?

An LCMS Analyst operates and maintains Liquid Chromatography-Mass Spectrometry (LC-MS) instruments to analyze chemical or biological samples. They prepare samples, calibrate equipment, interpret data, and ensure quality control in laboratory settings. LCMS Analysts work in industries such as pharmaceuticals, environmental science, and food safety to detect and quantify substances. Strong analytical skills, attention to detail, and knowledge of laboratory protocols are essential for this role.

What are the key skills and qualifications needed to thrive as an LCMS analyst?

To thrive as an LCMS Analyst, you need a solid background in analytical chemistry or biochemistry, with hands-on experience in liquid chromatography-mass spectrometry (LC-MS) techniques and a relevant science degree. Proficiency in operating and troubleshooting LC-MS instruments, data analysis software (such as Analyst or MassLynx), and potentially certifications like ASCP are highly valuable. Strong problem-solving skills, attention to detail, and the ability to communicate results clearly make you stand out in this position. These capabilities ensure accurate data interpretation, efficient laboratory workflows, and effective collaboration with research teams or clients.

What does a typical day look like for an LCMS analyst in a laboratory setting?

A typical day for an LCMS Analyst involves preparing and analyzing samples using liquid chromatography-mass spectrometry instruments, reviewing and validating data, and reporting results to senior scientists or project managers. You'll also maintain and calibrate laboratory equipment, troubleshoot technical issues, and ensure all analyses comply with quality standards and regulatory guidelines. Collaboration with colleagues, such as chemists, lab technicians, and quality assurance staff, is common for discussing methods, sharing findings, and streamlining lab operations. The role offers a mix of independent, hands-on work and team-based problem solving, making it both challenging and rewarding.

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Lcms Analyst jobs near you
Infographic showing various Lcms Analyst job openings in the United States as of August 2026, with employment types broken down into 89% Full Time, 6% Part Time, and 5% Contract. Highlights an 82% Physical, 7% Hybrid, and 11% Remote job distribution, with an average salary of $73,261 per year, or $35.2 per hour.

LCMS Scientist

Pioneer Data

Spring House, PA • On-site

Contractor

Re-posted yesterday

Job description

Position Details:
Our client, a world-leading Pharmaceutical Company in Spring House, PA is currently looking for a LCMS Scientist to join their expanding team.
 
Job Title: LCMS Scientist
Duration: 8 months contract, extendable up to 24 Months
Location: Spring House, PA
 
Note:
The client has the right-to-hire you as a permanent employee at any time during or after the end of the contract.
You may participate in the company group medical insurance plan
 
Description:
Overview
Be a part of a team developing state-of-the-art automation systems for mass spectrometry applied to biotherapeutics cell line development.
This role will leverage and develop the next phase of automation development in mass spectrometry supporting the Cell Engineering and Analytical Sciences group.
The role blends hands-on robotic operations, sample preparation, method development, and data analysis.
 
Notes:
Role is onsite 100% in Spring House, PA
Role is for 1 year at this time, regular business hours, NO TRAVEL
Bachelors degree is required
Mass spectometry required
LC-MS and sample prep required
Analyzing peptide mapping experience
Must have general lab skills
Will do programming, automation, but mass spectometry is required
Must have a willingness to learn and must be capable of learning
Will be managing samples D2D on mass spectometry
Experience with electronic lab notebooks
Must have Excel experience
Experience with Python, JavaScript, R
Must have a little industry experience
Top 2 Skills:
Mass spectometry
LC-MS experience

Job Description
Operating and validating robotic runs; monitoring performance, documenting deviations, and driving corrective action.
Develop and implement mass spectrometry assays to optimize protein expression levels, protein quality, and quantitation of biotherapeutics. Ensure accuracy and success of MS experiments through expertise in sample preparation.
Deploying, optimizing, maintaining, and continuously improving high-throughput workflows using liquid-handling robots and integrated automation workcells.
Analyze antibodies using peptide mapping, intact mass analysis, native mass spectrometry, and acoustic ejection mass spectrometry.
Troubleshooting instrumentation by coordinating with internal subject matter experts and external vendors to perform root cause analysis based on detailed scientific and technical investigations
Prepare and present scientific findings and recommendations to internal customers, project teams, and senior management.
Qualifications
Creative, independent problem‑solver with strong attention to detail and the ability to plan, prioritize, and deliver in a fast‑paced environment.
A minimum of a B.S. in Biology, Chemistry, Computer Science, Engineering, or a related field is requited. An advanced degree is preferred.
Strong organizational, time management, and interpersonal skills (both written and oral), and a commitment in close collaboration with scientists, vendors, and end users across seniority levels.
Previous hands on experience with executing protocols, pipetting and protein sample handling skills.
Experience with operating liquid handling systems (e.g., Hamilton, Tecan, Beckman) and/or basic programming experience (Python, JavaScript, R, C++/C#).
Hands on experience with LC-MS and associated sample preparation.