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It Applications Manager Jobs (NOW HIRING)

Ross Stores

Lead, IT Applications

Dublin, CA · On-site

$114K - $195K/yr

The IT Application Lead for Supply Chain -Workforce Management (WFM) Applications leads projects that apply new or existing technologies and solutions to solve business needs. This resource partners ...

Ross Stores

Lead, IT Applications

Dublin, CA · On-site

$114K - $195K/yr

The IT Application Lead for Supply Chain -Workforce Management (WFM) Applications leads projects that apply new or existing technologies and solutions to solve business needs. This resource partners ...

J. F. Ahern

IT Applications Specialist

Fond Du Lac, WI · On-site +1

We have an exciting opportunity for a IT Applications Specialist located in Fond du Lac, WI. How ... You'll also have the opportunity to write queries, create SSRS reports, manage process automations ...

Wynn Resorts

Analyst - IT Applications

Las Vegas, NV · On-site

Employ appropriate application maintenance, support and incident management processes and ... applications. * At least 5 years of information technology experience in a large-scale complex ...

Ross Stores

Lead, IT Applications

Dublin, CA · On-site

$114K - $195K/yr

The Lead, IT Applications (Self-Checkout - POS) is responsible for leading the design ... management, and root cause analysis • Identify and drive continuous improvements in SCO ...

ONEOK, Inc.

IT Applications Professional Intern

Tulsa, OK · On-site

$13.75 - $18.25/hr

As an intern, you'll have the opportunity to: * Support IT applications, systems, and technology initiatives * Assist with troubleshooting, system maintenance, and data management activities

Ross Stores

Lead, IT Applications

Dublin, CA · On-site

$114K - $195K/yr

The Lead, IT Applications (Self-Checkout - POS) is responsible for leading the design ... Technical Problem Solving & Root Cause Analysis Large-Scale Stores Deployment & Change Management ...

Ross Stores

Lead, IT Applications

Dublin, CA · On-site

$109K - $187K/yr

The Lead, IT Applications - Marketing Technology will provide hands-on technical leadership for the ... They will collaborate with the Business management, IT teams, and vendor teams to deliver necessary ...

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It Applications Manager information

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$33K

$115K

$158.5K

How much do it applications manager jobs pay per year?

As of Aug 22, 2026, the average yearly pay for it applications manager in the United States is $115,037.00, according to ZipRecruiter salary data. Most workers in this role earn between $96,000.00 and $134,500.00 per year, depending on experience, location, and employer.

What does an IT Applications Manager do?

An IT Applications Manager oversees the implementation, maintenance, and support of software applications within an organization. They are responsible for ensuring that applications run smoothly, meet business requirements, and are updated as needed. This role often involves coordinating with other IT professionals, managing projects, and working with vendors to evaluate and implement new solutions. Additionally, IT Applications Managers may supervise a team and develop strategies to optimize the use of technology to support business goals.

What does an IT Applications Manager do?

As an IT applications manager, your primary responsibilities are to manage the development and operational support of computer applications. Your duties are to oversee staff, assist with training of new employees, provide application enhancement, control the release process for applications, and offer ongoing support for internal departments and external users. You collaborate with other teams and vendors to implement changes, updates, and troubleshoot issues to find solutions. As a manager, you also ensure adherence to regulatory policies and procedures within the industry. An IT applications manager also prepares analysis and reports on active systems.

What are the key skills and qualifications needed to thrive as an IT Applications Manager?

To thrive as an IT Applications Manager, you need expertise in software development, application lifecycle management, and a bachelor's degree in computer science or a related field. Familiarity with systems such as ERP, CRM, project management tools, and certifications like PMP or ITIL are often required. Strong leadership, problem-solving, and communication skills help in managing teams and aligning IT solutions with business needs. These skills are crucial for ensuring efficient application performance, successful project delivery, and maximizing organizational value from IT investments.

What are some common challenges an IT Applications Manager faces when integrating new software solutions across departments?

IT Applications Managers often encounter challenges related to aligning new software solutions with existing business processes and ensuring compatibility with legacy systems. Coordinating between various departments to gather requirements and manage expectations can be complex, especially when users have differing needs or priorities. Additionally, ensuring data security and compliance during integration, as well as training staff to effectively use the new applications, are critical aspects that require careful planning and communication.

What is the difference between It Applications Manager vs Software Development Manager?

AspectIt Applications ManagerSoftware Development Manager
Primary FocusOverseeing application deployment, maintenance, and supportLeading software development projects and teams
Required SkillsIT infrastructure, application management, vendor coordinationSoftware design, coding, project management
Work EnvironmentIT departments, enterprise environmentsDevelopment teams, tech companies
CertificationsITIL, PMP, relevant vendor certificationsAgile, Scrum, PMP

The main difference is that It Applications Managers focus on managing and supporting existing applications within an organization, ensuring their stability and performance. In contrast, Software Development Managers lead the creation of new software products, overseeing development teams and project timelines. Both roles require strong project management skills and relevant certifications, but their core responsibilities and work environments differ.

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It Applications Manager jobs near you
Infographic showing various It Applications Manager job openings in the United States as of August 2026, with employment types broken down into 88% Full Time, 11% Part Time, and 1% Contract. Highlights an 81% Physical, 2% Hybrid, and 17% Remote job distribution, with an average salary of $115,037 per year, or $55.3 per hour.

Senior Manager, IT Laboratory Informatics

Regeneron Pharmaceuticals, Inc.

Troy, NY • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 23 days ago

Regeneron rating

8.4

Company rating: 8.4 out of 10

Based on 43 frontline employees who took The Breakroom Quiz

22nd of 86 rated pharmaceutical

Job description

Build our future together:
At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking an IT Applications Manager (Manager or Senior Manager) to join our IOPS IT team, overseeing the day-to-day maintenance, support, and development of Regeneron's IT Applications portfolio - including Empower CDS, SDMS, and other business-critical systems. In this role, you will lead a team of analysts, drive audit readiness and compliance, and ensure applications are maintained in a validated and compliant state - while collaborating closely with peer managers, QA, IT leadership, and global counterparts. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.
When & where:
  • Location: Troy, New York, United States
  • Work model: Monday - Friday 8am - 4:30pm

Discover your role:
  • Lead and develop a team of IT Applications analysts through performance management, coaching, mentoring, and goal setting; conduct monthly performance reviews and annual evaluations
  • Drive audit readiness across the application portfolio; serve as a key point of contact during FDA inspections and internal audits, ensuring systems, audit trails, and documentation are inspection-ready at all times
  • Ensure all supported applications are maintained in a compliant and validated state; proactively identify and resolve data integrity and compliance issues in accordance with 21 CFR Part 11, ALCOA+ principles, applicable SOPs, and policies
  • Maintain accuracy of system documentation including User Requirement Specifications, Design Specifications, Configuration Specifications, and Test Plans for validated systems
  • Collaborate closely with peer managers overseeing complementary application portfolios to ensure alignment, shared best practices, and coordinated delivery across the broader IOPS IT Applications function
  • Partner with global counterparts to support and maintain globally deployed QC systems in a consistent and compliant manner
  • Manage vendor relationships including performance, contract adherence, and delivery of services in line with business and regulatory compliance requirements
  • Develop and implement operational metrics and controls; drive continuous improvement initiatives that enhance workflows, system reliability, and team efficiency; contribute to the strategic vision of the IOPS IT Applications function
  • Strong knowledge of cGMP, GAMP, 21 CFR Part 11, and Annex 11; experience supporting applications in a highly regulated GMP laboratory or IT environment preferred
  • Demonstrated understanding of ALCOA+ principles and data integrity requirements in biopharmaceutical production
  • Proven ability to lead teams through FDA inspections and internal audits with confidence and thoroughness
  • Knowledge of Regulatory Asset Manager systems advantageous

This role requires:
  • Bachelor's degree in Information Technology, Science, Engineering, Computer Science, or a related field
  • Manager: 7+ years of relevant experience with 3+ years managing teams
  • Senior Manager: 8+ years of relevant experience with 4+ years managing teams
  • May consider experience in lieu of education. Level is determined based on qualifications relevant to the role

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.
Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.
Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about on-site expectations for your role and location.
As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.
For jobs in Canada: this posting is for an existing position.
Salary Range (annually)
$108,000.00 - $206,100.00

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