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Internship Cryo Electron Microscopy Jobs (NOW HIRING)

University of Colorado

Post-Doctoral Fellow

Aurora, CO · On-site

$49K - $67K/yr

By employing high-resolution cryo-electron microscopy (cryo-EM) and tomography (cryo-ET), we aim to capture the transient, high-order assemblies that trigger signaling in response to stress. In ...

University of Colorado

Post-Doctoral Fellow

Aurora, CO · On-site

$49K - $67K/yr

The Post-Doctoral Fellow will lead independent projects exploring transient and dynamic protein states using techniques such as cryo-electron microscopy, tomography, kinetic assays, and computational ...

University of Colorado

Post-Doctoral Fellow

Aurora, CO

$49K - $67K/yr

The Post-Doctoral Fellow will lead independent projects exploring transient and dynamic protein states using techniques such as cryo-electron microscopy, tomography, kinetic assays, and computational ...

Umd

Post-Doctoral Associate

College Park, MD · On-site

$62K - $75K/yr

IBBR leverages state-of-art integrative methods for bioanalytical, biophysical and structural characterization of biomolecules: cryo-electron microscopy, nuclear magnetic resonance, x-ray ...

Uw

Research Scientist/Engineer 3

Seattle, WA

At least 4 years of hands-on experience in cryo-electron microscopy, including sample preparation, data collection, image processing, and structure building. Experience with cryoEM structure ...

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How much do internship cryo electron microscopy jobs pay per hour?

As of Aug 19, 2026, the average hourly pay for internship cryo electron microscopy in the United States is $22.18, according to ZipRecruiter salary data. Most workers in this role earn between $18.27 and $25.96 per hour, depending on experience, location, and employer.

What is an internship in cryo electron microscopy?

An Internship in Cryo Electron Microscopy is a hands-on training position for students or recent graduates interested in learning about cryo-EM, a powerful imaging technique used to visualize biological molecules at near-atomic resolution. Interns typically assist with sample preparation, microscope operation, data collection, and image analysis under the guidance of experienced researchers. This internship provides valuable experience for those pursuing careers in structural biology, biochemistry, or related fields.

What types of hands-on experience can I expect during an internship in cryo electron microscopy?

As an intern in Cryo Electron Microscopy (Cryo-EM), you can expect to participate in sample preparation, operate electron microscopes under supervision, and assist with image acquisition and data processing. You'll often collaborate closely with experienced researchers and technicians, gaining exposure to state-of-the-art instrumentation and computational analysis tools. This role provides a unique opportunity to develop practical skills in a rapidly advancing field and can serve as a valuable stepping stone for future research or technical positions in structural biology.

What are the key skills and qualifications needed to thrive as an internship in cryo electron microscopy?

To excel in a Cryo Electron Microscopy internship, you need a solid background in biology, chemistry, or physics, typically at the undergraduate or graduate level, along with foundational laboratory skills. Familiarity with electron microscopes, image analysis software (such as RELION or CryoSPARC), and basic data processing tools is often required. Attention to detail, strong problem-solving abilities, and effective communication are vital soft skills for this position. These competencies are important to ensure accurate data collection, effective teamwork, and the advancement of research projects in a highly specialized scientific environment.

What is the difference between Internship Cryo Electron Microscopy vs Cryo Electron Microscopy Technician?

AspectInternship Cryo Electron MicroscopyCryo Electron Microscopy Technician
CredentialsTypically pursuing or recent graduate of relevant degreeRelevant degree or certification in microscopy or related field
Work EnvironmentEducational or research lab, internship settingResearch labs, biotech or pharmaceutical companies
ResponsibilitiesAssisting with sample prep, data collection, learning techniquesOperating cryo EM equipment, data acquisition, maintenance

Internship Cryo Electron Microscopy roles are entry-level, focused on learning and assisting in labs, often for students or recent grads. Cryo Electron Microscopy Technicians are more experienced, responsible for operating and maintaining equipment in professional research or industry settings. Both roles require knowledge of microscopy techniques, but the technician role demands more hands-on technical skills and experience.

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Internship Cryo Electron Microscopy jobs near you
Infographic showing various Internship Cryo Electron Microscopy job openings in the United States as of August 2026, with employment types broken down into 10% Internship, 56% Full Time, 32% Part Time, 1% Temporary, and 1% Contract. Highlights an 77% Physical, 2% Hybrid, and 21% Remote job distribution, with an average salary of $46,141 per year, or $22.2 per hour.

Postdoctoral Researcher - Zhou Lab

Buck Institute

Novato, CA • On-site

$73K - $81K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 13 days ago

Job description

Ribosome Biogenesis and Function
Position Summary
The Buck Institute for Research on Aging is seeking a highly motivated Postdoctoral Researcher to investigate the mechanisms governing ribosome biogenesis, remodeling, and function. Projects may focus on cytosolic and/or mitochondrial ribosomes and address questions related to ribosome assembly, composition, structure, localization, and translational activity.
The successful candidate will develop a mechanistic research program using one or more complementary approaches, including biochemistry, quantitative imaging, cryo-electron microscopy, and cryo-electron tomography. Applicants are not expected to have expertise in all these areas. Candidates with deep experience in ribosomes are strongly encouraged to apply, and the project will be shaped around the candidate’s scientific strengths, interests, and career goals.
Potential research directions include:
  • Defining ribosome assembly pathways, intermediates, and quality-control mechanisms.
  • Visualizing the spatial and temporal organization of ribosome biogenesis and function in living cells.
  • Linking genetic and biochemical perturbations to ribosome structure using cryo-EM and cryo-electron tomography.
  • Understanding how metabolism and stress remodel ribosomes.

About the Zhou Lab
The Zhou Lab studies how the cellular proteome changes its organization and function in response to environmental conditions, stress, and aging. We use model systems ranging from budding yeast to cultured human cells. The lab combines molecular and cell biology, biochemistry, quantitative proteomics, high-throughput screening, automated and super-resolution microscopy, cryo-EM/cryo-ET, computational analysis, and machine learning. Our multidisciplinary team includes researchers with backgrounds in biology, biophysics, and artificial intelligence.
The successful candidate will receive close scientific mentorship while being encouraged to develop intellectual independence. The Buck provides access to advanced core facilities, a highly collaborative aging-research community, and professional-development opportunities in scientific writing, fellowship applications, presentations, leadership, and career planning.
Required Qualifications
  • PhD completed by the start date in molecular cell biology, biochemistry, structural biology, biophysics, or a related field.
  • Strong research experience in relevant approach, such as biochemistry, quantitative imaging, cryo-EM/cryo-ET.
  • Evidence of rigorous and productive research, including first-author publications.
  • Ability to design and execute experiments, analyze quantitative data, and troubleshoot independently.
  • Ability to work collaboratively in a multidisciplinary environment and communicate effectively in written and spoken English.

Preferred Experience
  • Prior work on ribosomes, translation, proteostasis, or macromolecular-complex assembly.
  • Experience with budding yeast or mammalian cell culture, protein purification, ribosome profiling, quantitative proteomics, fluorescence microscopy, or single-particle cryo-EM.
  • Interest in learning complementary methods and in integrating mechanistic experiments across scales.

Selected Recent Publications
Zheng F, et al. Metabolic environment-driven remodeling of mitochondrial ribosomes regulates translation and biogenesis. Molecular Cell. 2025.
Liu Q, et al. Mitochondria-lysosome coupling contributes to lysosome acidification and aging. Molecular Cell. 2026.
Yoo S, et al. The spatiotemporal proteome landscape of aging: Structural determinants of age-sensitive proteome remodeling. bioRxiv. 2026. doi:10.64898/2026.02.26.708310.
Liu Q, et al. Nascent mitochondrial proteins initiate the localized condensation of cytosolic protein aggregates on the mitochondrial surface. Proceedings of the National Academy of Sciences USA. 2023;120:e2300475120.
Compensation and Benefits
  • $73,760 - $81,440 annually, depending on qualifications and experience
  • Comprehensive benefits include medical, dental, and vision coverage; paid time off and parental leave; a 401(k) employer contribution; and a student-debt repayment option.

About the Buck Institute
The Buck Institute is the first independent biomedical research institute in the United States devoted solely to research on aging. Located in Novato, California, the Buck brings together scientists across disciplines to study the mechanisms of aging and age-related disease and to help people live better, longer.
The Buck Institute is an equal opportunity employer. We strongly encourage applications from candidates whose experiences and perspectives will contribute to the diversity and excellence of our community.
To Apply
Please submit the following through the Buck Institute careers portal:
  • A curriculum vitae
  • A cover letter describing your prior research, the ribosome questions or projects that most interest you, and how this position fits your future goals
  • Contact information for three professional references
  • Representative publications or other relevant research products, as appropriate.

Learn more about the Zhou Lab: www.buckinstitute.org/lab/zhou-lab/
 

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