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Entry Level Cryo Electron Microscopy Jobs (NOW HIRING)

Brookhaven National Laboratory

Cryo-EM Scientist

Upton, NY · On-site

$103K - $138K/yr

The national cryo-electron microscopy (cryo-EM) center, the Laboratory for BioMolecular Structure (LBMS) at Brookhaven National Laboratory, provides sample preparation, screening, and high-resolution ...

Guidehouse

Electron Microscope Scientist

Bethesda, MD · On-site

$74K - $124K/yr

A minimum of THREE (3) years of experience in cryo-electron microscopy, structural biology, or related research. * Demonstrated expertise in cryo-EM workflows, instrumentation, and facility ...

Guidehouse

Electron Microscope Scientist

Bethesda, MD

$74K - $124K/yr

A minimum of THREE (3) years of experience in cryo-electron microscopy, structural biology, or related research. * Demonstrated expertise in cryo-EM workflows, instrumentation, and facility ...

University of Colorado

Post-Doctoral Fellow

Aurora, CO

$49K - $67K/yr

By employing high-resolution cryo-electron microscopy (cryo-EM) and tomography (cryo-ET), we aim to capture the transient, high-order assemblies that trigger signaling in response to stress. In ...

University of Colorado

Post-Doctoral Fellow

Aurora, CO · On-site

$49K - $67K/yr

The Post-Doctoral Fellow will lead independent projects exploring transient and dynamic protein states using techniques such as cryo-electron microscopy, tomography, kinetic assays, and computational ...

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How much do entry level cryo electron microscopy jobs pay per hour?

As of Jul 28, 2026, the average hourly pay for entry level cryo electron microscopy in the United States is $19.18, according to ZipRecruiter salary data. Most workers in this role earn between $17.31 and $20.43 per hour, depending on experience, location, and employer.

What is the difference between Entry Level Cryo Electron Microscopy vs Entry Level Transmission Electron Microscopy?

AspectEntry Level Cryo Electron MicroscopyEntry Level Transmission Electron Microscopy
CredentialsBachelor's degree in biology, chemistry, or related field; training in cryo techniquesBachelor's degree in materials science, physics, or related field; basic microscopy training
Work EnvironmentResearch labs, biotech, or pharmaceutical companies focusing on biological samplesMaterials labs, research institutions, or industrial settings analyzing materials or biological specimens
Industry UsagePrimarily in biological and biomedical researchUsed across materials science, biology, and nanotechnology sectors

Entry Level Cryo Electron Microscopy and Entry Level Transmission Electron Microscopy share foundational microscopy skills but differ in sample preparation, application focus, and industry usage. Cryo EM specializes in imaging frozen biological samples, while TEM is more versatile across biological and material sciences. Both roles require similar educational backgrounds and entry-level training, but their work environments and applications vary.

What are some common challenges faced by entry-level professionals in Cryo Electron Microscopy, and how can they be overcome?

Entry-level professionals in Cryo Electron Microscopy (Cryo-EM) often encounter challenges such as mastering complex instrumentation, learning sample preparation techniques, and interpreting large volumes of data. Gaining hands-on experience under the guidance of experienced colleagues and participating in specialized training workshops can help build confidence and technical proficiency. Regular communication with team members, including biologists, physicists, and data analysts, is also crucial for troubleshooting issues and ensuring successful project outcomes.

What are entry level cryo electron microscopy jobs?

Entry level cryo electron microscopy (cryo-EM) jobs are positions designed for individuals who are new to the field and want to gain hands-on experience with cryo-EM technology. These roles typically involve assisting with sample preparation, operating the electron microscope under supervision, maintaining equipment, and analyzing data under the guidance of senior scientists. Candidates usually have a background in biology, chemistry, physics, or a related field, and may be recent graduates or new to microscopy. Entry level roles provide valuable training and foundational skills for a career in structural biology or advanced microscopy research.

What key skills and qualifications are needed to thrive as an Entry Level Cryo Electron Microscopy (Cryo-EM) Technician, and why are they important?

To thrive as an Entry Level Cryo Electron Microscopy Technician, a solid background in biology, chemistry, or physics and a bachelor’s degree in a relevant scientific field are essential. Familiarity with cryo-EM instrumentation, sample preparation protocols, and data analysis software such as RELION or CryoSPARC is typically required. Attention to detail, strong problem-solving abilities, and effective teamwork are standout soft skills in this role. These competencies ensure accurate data collection, high-quality imaging, and reliable scientific results in a collaborative research environment.
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Entry Level Cryo Electron Microscopy jobs near you
Infographic showing various Entry Level Cryo Electron Microscopy job openings in the United States as of July 2026, with employment types broken down into 85% Full Time, 5% Part Time, 5% Contract, 1% Nights, and 4% Summer. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $39,900 per year, or $19.2 per hour.
Cryo-EM Scientist

Cryo-EM Scientist

Brookhaven National Laboratory

Upton, NY • On-site

$103K - $138K/yr

Full-time

Posted 2 days ago

Job description

The national cryo-electron microscopy (cryo-EM) center, the Laboratory for BioMolecular Structure (LBMS) at Brookhaven National Laboratory, provides sample preparation, screening, and high-resolution data collection for both single-particle cryo-EM and cryo-electron tomography (cryo-ET) studies.
The facility currently hosts one high-end Krios microscope, one Talos 120C and one JEM 2100 screening electron microscopes, an Aquilos2 cryo-focused-ion beam scanning electron microscope (cryo-FIB-SEM), an EM ICE high-pressure freezer, and cryo-grids preparation equipment.
Position Description
The LBMS is seeking an experienced scientist to join our team and support our efforts in operation and improvement of LBMS cryo-EM capabilities. The cryo-EM scientist will help users obtain high-quality Cryo-EM data, lead cryo-EM efforts on collaboration projects, participate in LBMS 3-tier training program, and develop/implement new methods.
The successful candidate will have a strong background in biology, and experience with cryo-EM techniques.
Essential Duties and Responsibilities:
  • Operate and maintain cryo-EMs and related equipment, including sample preparation and image acquisition.
  • Train, support and educate users and the public through the 3-tier training program.
  • Collaborate with users to design and optimize experiments; provide guidance on sample preparation, data collection, and analysis.
  • Communicate with academic and industrial user communities and provide support.
  • Contribute to method development in cryo-EM and support overall LBMS operations.

Required Knowledge, Skills, and Abilities:
  • PhD in a relevant field (e.g., biology, biochemistry, biophysics, chemistry, microbiology, virology) with ≥2 years postdoctoral experience.
  • Effective and constructive communicator.
  • Ability to work both independently as a self-starter and as a proactive team player.
  • Ability to maintain a flexible schedule, including evenings and weekends, to support continuous facility operations and user needs.
  • Strong organizational and record-keeping skills.
  • Experience in at least one of the following: cryo-EM instrumentation, sample preparation, high-resolution single particle data collection, or cryo-electron tomography.

Preferred Knowledge, Skills, and Experience in one or more of the following:
  • Single-particle image processing using CryoSPARC, Relion, cisTEM, EMAN2, or similar software.
  • Tomography image processing using IMOD, AreTomo, EMAN2, or related packages.
  • Cryogenic sample preparation using cryo-FIB or cryo-microtome.
  • Fluorescence light microscopy for correlative or complementary studies.
  • Experience in working in a Linux/UNIX environment.
  • Strong record of peer-reviewed publications.

Other Information:
  • Candidates should submit a CV/resume, a cover letter and contact information for three references.
  • Brookhaven Laboratory is committed to providing fair, equitable and competitive compensation. This is a multi-level role and the full salary range for this position is $103,000 - $138,000 / year. You will be placed at the level and salary commensurate with your experience. Salary offers will be commensurate with the final candidate's qualification, education and experience and considered with the internal peer group.

Brookhaven National Laboratory is committed to employee success and we believe that a comprehensive employee benefits program is an important and meaningful part of the compensation employees receive. Review more information at BNL | Benefits Program
Brookhaven National Laboratory requires all non-badged personnel including visitors to produce a REAL-ID or REAL-ID compliant documentation to access Brookhaven National Laboratory - view more information at www.bnl.gov/real-id. This is due to nationwide identification requirements for federal site access as required by the federal REAL ID Act. Those not in possession of a REAL ID-compliant document will not be permitted to access the site which includes access to the Laboratory for interviews.
About Us
Brookhaven National Laboratory (www.bnl.gov) delivers discovery science and transformative technology to power and secure the nation's future. Brookhaven Lab is a multidisciplinary laboratory with seven Nobel Prize-winning discoveries, 37 R&D 100 Awards, and more than 70 years of pioneering research. The Lab is primarily supported by the U.S. Department of Energy's (DOE) Office of Science. Brookhaven Science Associates (BSA) operates and manages the Laboratory for DOE. BSA is a partnership between Battelle and The Research Foundation for the State University of New York on behalf of Stony Brook University. BSA salutes our veterans and active military members with careers that leverage the skills and unique experience they gained while serving our country, learn more at BNL | Opportunities for Veterans at Brookhaven National Laboratory.
Equal Opportunity/Affirmative Action Employer
Guided by our core values of integrity, responsibility, innovation, respect, and teamwork, Brookhaven Science Associates is an Equal Employment Opportunity Employer-Vets/Disabled. We are committed to fostering a respectful and collaborative environment that fuels scientific discovery. We consider all qualified applicants without regard to any characteristic protected by law. All qualified individuals are encouraged to apply. We ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. *VEVRAA Federal Contractor
BSA employees are subject to restrictions related to participation in Foreign Government Talent Recruitment Programs, as defined and detailed in United States Department of Energy Order 486.1A. You will be asked to disclose any such participation at the time of hire for review by Brookhaven. The full text of the Order may be found at: https://www.directives.doe.gov/directives-documents/400-series/0486.1-BOrder-a/@@images/file

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