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Assistant Cryo Electron Microscopy Jobs (NOW HIRING)

Axle

Cryo-Electron Microscopy Specialist

Hamilton, MT · On-site

$90K - $110K/yr

Dependent Care Assistant Program (DCAP) * Transportation Reimbursement Account (TRN) About the Role ... Cryo-electron microscopist to join the Research Technologies Branch (RTB), Electron Microscopy Unit ...

New

Axle

Cryo-Electron Microscopy Specialist

Hamilton, MT · On-site

Dependent Care Assistant Program (DCAP) * Transportation Reimbursement Account (TRN) About the Role ... Cryo-electron microscopist to join the Research Technologies Branch (RTB), Electron Microscopy Unit ...

New

Axle

Cryo-Electron Microscopy Specialist

Hamilton, MT · On-site

$90K - $110K/yr

Dependent Care Assistant Program (DCAP) * Transportation Reimbursement Account (TRN) About the Role ... Cryo-electron microscopist to join the Research Technologies Branch (RTB), Electron Microscopy Unit ...

Axle

Electron Microscopy Specialist

Hamilton, MT · On-site

Dependent Care Assistant Program (DCAP) * Transportation Reimbursement Account (TRN) About the Role ... Help bring new capabilities online, including techniques like CLEM, FIB-SEM, and cryo-EM. * Keep ...

Axle

Electron Microscopy Specialist

Hamilton, MT · On-site

$70K - $80K/yr

Dependent Care Assistant Program (DCAP) * Transportation Reimbursement Account (TRN) About the Role ... Help bring new capabilities online, including techniques like CLEM, FIB-SEM, and cryo-EM. * Keep ...

Axle

Electron Microscopy Specialist

Hamilton, MT

$70K - $80K/yr

Dependent Care Assistant Program (DCAP) * Transportation Reimbursement Account (TRN) About the Role ... Help bring new capabilities online, including techniques like CLEM, FIB-SEM, and cryo-EM. * Keep ...

FHLB Des Moines

Research Scientist/Engr 4

Seattle, WA · On-site

$122K/yr

Single particle cryo-electron microscopy and X-ray crystallization of viral glycoproteins, immunogen design, virology, biochemistry and biophysics.**Purpose of the Research Project(s):**The goal of ...

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Assistant Cryo Electron Microscopy information

What is an assistant cryo electron microscopy?

An Assistant Cryo Electron Microscopy (Cryo-EM) professional is responsible for supporting the operation and maintenance of cryo-electron microscopes in scientific research facilities. They assist senior scientists with sample preparation, microscope calibration, data collection, and basic troubleshooting. Their role is crucial in ensuring that high-quality images of biological or material samples are obtained at extremely low temperatures, which is essential for understanding structures at the molecular level. Assistant Cryo-EM staff may also help with training users and maintaining lab protocols.

What are the typical daily responsibilities of an assistant cryo electron microscopy?

As an Assistant Cryo-EM specialist, your daily tasks typically include preparing biological or material samples for imaging, operating the cryo-electron microscope under supervision, and performing routine maintenance and calibration of equipment. You may also assist with data collection, image processing, and documentation to support research projects. Collaboration with principal investigators, lab technicians, and data analysts is common, ensuring accurate results and maintaining laboratory standards.

What are the key skills and qualifications needed to thrive as an assistant cryo electron microscopy?

To thrive as an Assistant Cryo Electron Microscopy Technician, you need a strong background in biology, chemistry, or physics, often with a relevant bachelor's or master's degree. Familiarity with cryo-EM instrumentation, sample preparation techniques, and image processing software such as RELION or CryoSPARC is typically required. Attention to detail, problem-solving abilities, and effective communication help ensure accurate data collection and collaboration with research teams. These skills are vital for producing high-quality results and supporting advanced structural biology research.

What is the difference between Assistant Cryo Electron Microscopy vs Assistant Electron Microscopy?

AspectAssistant Cryo Electron MicroscopyAssistant Electron Microscopy
CredentialsTypically requires a bachelor's or master's in biology, biochemistry, or related fieldsSimilar educational background, often with additional microscopy certifications
Work EnvironmentSpecialized cryo-EM labs with cryogens and advanced imaging equipmentGeneral microscopy labs, including SEM and TEM facilities
Industry UsagePrimarily in structural biology, biochemistry, and pharmaceutical researchBroader applications across materials science, biology, and nanotechnology

Assistant Cryo Electron Microscopy focuses on preparing and imaging biological samples at cryogenic temperatures using cryo-EM technology, while Assistant Electron Microscopy covers a wider range of microscopy techniques, including SEM and TEM, often in more general lab settings. Both roles require similar educational backgrounds but differ in specialized equipment and research focus.

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Assistant Cryo Electron Microscopy jobs near you
Infographic showing various Assistant Cryo Electron Microscopy job openings in the United States as of September 2026, with employment types broken down into 2% As Needed, 74% Full Time, 21% Part Time, 1% Temporary, and 2% Contract. Highlights an 97% Physical, 1% Hybrid, and 2% Remote job distribution.

Cryo-Electron Microscopy Specialist

Hamilton, MT • On-site

Axle
See more jobs at Axleexternal

$90K - $110K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 3 days ago

New

Job description

(ID: 2026-3478)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

About the Role

We are looking for a skilled Cryo-electron microscopist to join the Research Technologies Branch (RTB), Electron Microscopy Unit (EMU). This position is based at Rocky Mountain Laboratories (RML) in Hamilton, Montana. In this role, you'll work closely with scientists in a collaborative, fast-paced environment, helping generate high-quality data that supports infectious disease research.

This is a hands-on position for someone who enjoys both the technical side of electron microscopy and the collaborative nature of working with different research groups. If you have strong cryo-EM experience and are excited about learning and applying newer approaches like room-temperature EM, FIB-SEM, and cryo-EM, this could be a great fit.

What You'll Do

  • Perform negative staining on purified proteins to evaluate sample quality.

  • Prepare biological samples for cryo-EM (plunge freezing) and perform imaging and analysis.

  • Operate and help maintain TEM and other ancillary instruments, including troubleshooting when needed.

  • Work closely with NIAID investigators to plan experiments, interpret results, and solve technical challenges.

  • Help bring new capabilities online, including techniques like CLEM, FIB-SEM, and cryo-EM.

  • Keep clear, well-organized records in line with NIH standards for rigor and reproducibility.

  • Train and support other lab members or facility users in EM techniques and image processing.

  • Contribute to the overall operation of the lab, including equipment upkeep and safety compliance.

What We're Looking For

  • Master's degree or higher in a relevant field (Cell Biology, Structural Biology, Biophysics, or similar).

  • Solid understanding of EM sample preparation and imaging workflows.

  • Experience operating and troubleshooting EM instruments.

  • Someone who communicates well, works collaboratively, and is comfortable supporting multiple projects.

Nice to Have

Experience with, or strong interest in learning:

  • Room temperature electron microscopy

  • Correlative Light and Electron Microscopy (CLEM)

  • Focused Ion Beam-SEM (FIB-SEM)

  • Familiarity with image analysis tools.

What Makes Someone Successful in This Role

  • You're a team player who enjoys working with a range of scientists and projects.

  • You're curious and motivated to learn new techniques and technologies.

  • You're organized, detail-oriented, and take pride in producing high-quality data.

  • You can balance multiple priorities without losing track of the details.

Location: Rocky Mountain Laboratories in Hamilton, Montana.

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle's employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate's experience, qualifications, skills, and location.

#IND

Salary Range
$90,000—$110,000 USD