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Home Based Principal Investigator Jobs (NOW HIRING)

Altasciences

Principal Investigator

Overland Park, KS · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

The Principal Investigator will promote Good Clinical Practices (GCP) during the conduct of ... Ensure subject eligibility is met based on protocol inclusionary/exclusionary criteria and that the ...

Altasciences

Principal Investigator

Overland Park, KS · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

The Principal Investigator will promote Good Clinical Practices (GCP) during the conduct of ... Ensure subject eligibility is met based on protocol inclusionary/exclusionary criteria and that the ...

Kelly Services

Principal Investigator

West Hills, CA · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Principal Investigator (Internal Medicine) Kelly Science and Clinical is currently hiring a ... The exact hours will vary based on the needs of the clinical trial study, offering both ...

Olsson

Principal Investigator

Denver, CO · On-site +1

$150K - $240K/yr

As the Principal Investigator you will plan, oversee, and support cultural resources investigations ... will vary based on factors such as experience, qualifications, geographic location, skills ...

Olsson

Principal Investigator

Colorado Springs, CO · On-site

$150K - $240K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

As the Principal Investigator you will plan, oversee, and support cultural resources investigations ... will vary based on factors such as experience, qualifications, geographic location, skills ...

Actalent

Principal Investigator

Houston, TX · On-site

$270K - $312K/yr

Job Title: Principal Investigator (Part Time) As a Principal Investigator, you will lead and ... Job Type & Location This is a Permanent position based out of Houston, TX. Pay and Benefits The pay ...

Medix

Principal Investigator

Chicago, IL · On-site

$125 - $200/hr

  • Medical

  • Dental

  • Vision

  • Retirement

Job Summary Our client seeks a dedicated Principal Investigator responsible for conducting ... Eligibility for health benefits is based on verifying that an average of 30 hours per week during ...

Lonza

Principal Investigator

Tampa, FL · On-site

  • Medical

  • Dental

  • Vision

Job Title Principal Investigator Location Tampa, FL This role is based at our Tampa, Florida site, where you will serve as the technical and scientific lead for complex client programs, driving ...

Pinnacle Clinical Research

Principal Investigator

Austin, TX · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

One to two years of research experience as a principal investigator is preferred. * At least one to ... web-based enterprise solutions software. Work Environment and Physical demands: The work ...

Lonza

Principal Investigator

Tampa, FL

  • Medical

  • Dental

  • Vision

Job Title Principal Investigator Location Tampa, FL This role is based at our Tampa, Florida site, where you will serve as the technical and scientific lead for complex client programs, driving ...

Pinnacle Clinical Research

Principal Investigator

Houston, TX · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

One to two years of research experience as a principal investigator is preferred. * At least one to ... web-based enterprise solutions software. Work Environment and Physical demands: The work ...

Pinnacle Clinical Research

Principal Investigator

Austin, TX · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

One to two years of research experience as a principal investigator is preferred. * At least one to ... web-based enterprise solutions software. Work Environment and Physical demands: The work ...

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All JobsHome Based Principal Investigator Jobs

Home Based Principal Investigator information

See salary details

$19.5K

$142.7K

$260.5K

How much do home based principal investigator jobs pay per year?

As of Aug 13, 2026, the average yearly pay for home based principal investigator in the United States is $142,668.00, according to ZipRecruiter salary data. Most workers in this role earn between $86,000.00 and $200,000.00 per year, depending on experience, location, and employer.

What is the difference between Home Based Principal Investigator vs Clinical Research Coordinator?

AspectHome Based Principal InvestigatorClinical Research Coordinator
Required credentialsMedical degree or relevant advanced degree, research experienceBachelor's degree, research training, certification often preferred
Work environmentLeading research projects, overseeing study conduct, often remotely or in clinicsManaging daily study activities, recruiting participants, data collection
Employer and industry usageResearch institutions, hospitals, pharmaceutical companiesResearch sites, hospitals, clinics

The Home Based Principal Investigator typically holds advanced medical credentials and oversees clinical studies, often working remotely or in clinical settings. In contrast, a Clinical Research Coordinator manages day-to-day study tasks, focusing on participant recruitment and data collection. Both roles are essential in clinical research but differ in responsibilities, credentials, and work environment.

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The most popular types of Principal Investigator jobs are:

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Home Based Principal Investigator jobs near you
Infographic showing various Home Based Principal Investigator job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 77% Full Time, 15% Part Time, and 7% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $142,668 per year, or $68.6 per hour.

Principal Investigator

Altasciences

Overland Park, KS • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 8 days ago

Altasciences rating

7.6

Company rating: 7.6 out of 10

Based on 17 frontline employees who took The Breakroom Quiz

59th of 120 rated laboratories

Job description

Your New Company!
At Altasciences we all move in unison to assist and work in the discovery, development, and manufacturing of new drug therapies to get them faster to people who need them. No matter your role, we all play an important part and you will have a significant impact on the health and well-being of people across the globe. By living our values of Employee Development, Customer Focus, Quality and Excellence, Respect and Integrity, we look to foster a passionate and collaborative work environment and we are looking for talented and enthusiastic people, like you, to join our growing team! Whether you're a recent college graduate or seeking your next career opportunity, it's time to discover your future at Altasciences.
We are better together and together We Are Altasciences.
About The Role
The Principal Investigator is responsible for the supervision and delegation of the tasks related to the clinical trial they are Principal Investigator of. The Principal Investigator will promote Good Clinical Practices (GCP) during the conduct of clinical investigations by ensuring adherence to protocol requirements, protecting the rights and welfare of subjects, assuring the integrity of data generated at the site and directing the conduct of the clinical investigation according to regulation/guidance and standard operating procedure (SOP).
You'll Do Here
  • Supervise the clinical activities for the clinical trial they are Principal Investigator.
  • Delegation of trial related tasks and the review of employees on the Delegation of Authority and Signature Log per job title/training record.
  • Perform protocol training.
  • Provide documentation for the Sub-Investigators.
  • Ensure subject safety at all times, this may include but is not limited to: review of clinical laboratory results and/or other test results. Review and/or performance of vital signs, ECGs or other safety tests.
  • Perform critical trial related tasks and/or make trial related decisions during the course of the trial.
  • Ensure subject eligibility is met based on protocol inclusionary/exclusionary criteria and that the subject continues to meet eligibility criteria throughout the course of a clinical trial.
  • Ensure requirements related to obtaining informed consent are met.
  • Perform physical examinations and medical history intake and review.
  • Be on-site for surveillance as required by protocol and remain available on-call for medical events.
  • Record and follow-up on adverse events and determine causality.
  • Report serious adverse events to appropriate parties.
  • Participate in sponsor visits and regulatory audits.
  • Document study related events incompliance with GCP.
  • Review study protocols and SOPs.
  • Complete and/or review regulatory documents as applicable.
  • Participate in sponsor visits and regulatory audits.
  • May act as Sub-Investigator on studies not assigned to them as Principal Investigator.

What You'll Need to Succeed
  • MD degree from an accredited Physician Program and Advanced Cardiac Life Support (ACLS) certification required.
  • Previous experience with similar responsibilities; ideally related to the industry.

What We Offer
Altasciences offers a wide variety of benefits to help our employees live healthy and fulfilling lives both at and outside of work.
Altasciences' Benefits Package Includes:
  • Health/Dental/Vision Insurance Plans
  • 401(k)/RRSP with Employer Match
  • Paid Vacation and Holidays
  • Paid Sick and Bereavement Leave
  • Employee Assistance & Telehealth Programs

Altasciences' Incentive Programs Include:
  • Training & Development Programs
  • Employee Referral Bonus Program

#LI-AN1
MOVING IN UNISON TO DELIVER A BIG IMPACT WITH A PERSONAL TOUCH
Altasciences is an equal opportunity employer committed to diversity and inclusion. Our goal is to attract, develop and retain highly talented employees from diverse backgrounds, allowing us to benefit from a wide variety of experiences and perspectives. All qualified applicants will receive consideration for employment without regard to age, race, color, religion, creed, sex, sexual orientation, gender identity, national origin, disability or any other protected grounds under applicable legislation. Reasonable accommodations for persons with disabilities during the recruitment process are available upon request. Join us at Altasciences!

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