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High Content Imaging Jobs (NOW HIRING)

You will lead the design of a knowledge graph to link diverse data sources, including high-content imaging, sequencing (WGS, WTS, scRNA, and others), MOS model characteristics, clinical and disease ...

... high-content imaging data. * Analyze data from drug perturbation screens to identify transcriptomic signatures, compound-gene associations, and patterns of drug response across disease-relevant cell ...

$46K - $63K/yr

The candidate will perform electrophysiology and molecular biology experiments, analyze mitochondrial function, conduct live-cell and high-content imaging studies, perform mouse behavioral assays ...

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High Content Imaging information

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How much do high content imaging jobs pay per hour?

As of Jun 29, 2026, the average hourly pay for high content imaging in the United States is $38.91, according to ZipRecruiter salary data. Most workers in this role earn between $26.20 and $45.19 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a High Content Imaging Specialist, and why are they important?

To thrive as a High Content Imaging Specialist, expertise in cell biology, image analysis, and microscopy, often with an advanced degree in a life science field, is essential. Familiarity with high-throughput imaging platforms (such as PerkinElmer Opera Phenix or Molecular Devices ImageXpress), image analysis software (like CellProfiler or ImageJ), and data management systems is typically required. Strong problem-solving skills, attention to detail, and effective communication are crucial for optimizing assays and collaborating with cross-functional teams. These competencies ensure accurate data acquisition, reliable experimental results, and successful integration of imaging technologies in research workflows.

What are some common challenges faced by professionals working in High Content Imaging, and how can they be addressed?

Professionals in High Content Imaging often encounter challenges such as managing large volumes of data, ensuring image quality and consistency, and troubleshooting complex imaging equipment. These challenges can be addressed by developing strong data management skills, staying current with image analysis software, and collaborating closely with IT and instrument support teams. Additionally, regular training on new technologies and maintaining clear documentation can help ensure smooth workflows and minimize downtime.

What is high content imaging?

High content imaging is an advanced microscopy technique used primarily in biological and pharmaceutical research to capture and analyze large volumes of complex cellular data. It combines high-resolution imaging with automated data analysis to assess multiple cellular features simultaneously, making it a powerful tool for drug discovery, toxicity testing, and cell biology studies. This approach enables researchers to gather quantitative information from thousands of cells in a single experiment, increasing efficiency and data quality. High content imaging often uses fluorescence labeling and sophisticated software to extract meaningful biological insights from images.

What is the difference between High Content Imaging vs Cell Imaging Specialist?

AspectHigh Content ImagingCell Imaging Specialist
Required CredentialsBachelor's or higher in biology, biochemistry, or related fields; experience with microscopy and imaging softwareSimilar credentials; often includes microscopy and cell biology expertise
Work EnvironmentResearch labs, pharmaceutical companies, biotech firmsLaboratories focusing on cell analysis, drug discovery, or biomedical research
Industry UsageUsed across biotech, pharma, academic researchPrimarily in research and development settings within biotech and pharma
Common Search/ComparisonHigh Content Imaging vs Cell Imaging Specialist

High Content Imaging involves automated microscopy and image analysis to study cellular responses on a large scale, often used in drug screening. Cell Imaging Specialist focuses on detailed microscopy of cells, emphasizing manual or semi-automated imaging techniques. While both roles require microscopy skills and biological knowledge, High Content Imaging emphasizes high-throughput analysis, whereas Cell Imaging Specialists focus on detailed cellular visualization.

What jobs pay $10,000 a month without a degree?

High Content Imaging roles typically require specialized skills and often a degree, but some related fields like sales, real estate, or technical consulting can pay $10,000 or more monthly without a formal degree, especially with experience and performance. High-paying jobs in these areas often involve commission, bonuses, or freelance work, and success depends on skills, network, and industry knowledge.

What jobs pay 2000 a day?

High Content Imaging roles typically do not pay $2000 a day; such high daily rates are more common in specialized consulting, executive-level positions, or freelance work in fields like finance, law, or technology. Most imaging-related jobs offer salaries or hourly rates that are significantly lower, often depending on experience, location, and industry demand.

What imaging job pays the most?

High Content Imaging specialists or roles involving advanced microscopy and image analysis tend to have higher salaries within imaging jobs, especially when combined with skills in data analysis, software tools, and research experience. Senior positions, such as imaging managers or specialists with extensive expertise, can earn higher wages, often exceeding $80,000 annually depending on the industry and location.
More about High Content Imaging jobs
What cities are hiring for High Content Imaging jobs? Cities with the most High Content Imaging job openings:
What states have the most High Content Imaging jobs? States with the most job openings for High Content Imaging jobs include:
What job categories do people searching High Content Imaging jobs look for? The top searched job categories for High Content Imaging jobs are:
Scientist, Complex in Vitro Systems (Lung Focus)

Scientist, Complex in Vitro Systems (Lung Focus)

Software Guidance & Assistance

South San Francisco, CA โ€ข On-site

Other

Posted 16 days ago


Key responsibilities

  • Develop, qualify, and implement advanced in vitro lung model systems for disease modeling and lung safety risk assessment.

  • Design and execute experiments to characterize lung models using techniques such as cytotoxicity assays, imaging, and molecular analyses.

  • Collaborate with cross-functional teams and maintain comprehensive electronic documentation in accordance with departmental procedures.


Job description

Software Guidance & Assistance, Inc., (SGA), is searching for a Scientist, Complex in Vitro Systems (Lung Focus) for a contract assignment with one of our premier Pharmaceutical Services clients in South San Francisco, CA .
Responsibilities :
The Complex in Vitro Systems (CiS) Lab within the Department of Translational Safety is seeking a highly motivated Scientist to develop, characterize, and qualify advanced complex in vitro models to support the firm's mission of delivering safe and efficacious medicines. The CiS group partners closely with colleagues across Development Sciences, Translational Medicine, and Research to establish and implement innovative platforms that enable target assessment, lead optimization, and safety evaluation across a dynamic portfolio, novel modalities, and emerging therapeutic areas.
In this lab-based role, you will provide scientific and technical expertise to support the development and implementation of human lung complex in vitro models (CIVM), including lung organoids, air-liquid interface (ALI) cultures, and lung microphysiological systems for drug development. Responsibilities include culturing and characterizing state-of-the-art lung CIVM models, designing and executing model qualification and characterization studies (e.g., advanced imaging, transcriptomics, and functional and phenotypic assays), analyzing and interpreting complex datasets, and maintaining rigorous, high-quality documentation. The Scientist will be expected to share scientific insights across functional teams, contribute to cross-disciplinary collaborations, and support internal and external publication efforts.
This position is ideal for an experienced scientist passionate about advancing disease modeling and translational safety through innovative complex in vitro. The successful candidate will excel in a dynamic, collaborative research environment, demonstrate exceptional problem-solving skills, and effectively communicate across scientific disciplines to contribute to the development of cutting-edge ocular disease models and help shape the future of ocular drug discovery and development.
  • Development, qualification, and implementation of innovative in vitro lung model systems (e.g., airway and alveolar organoids, ALI cultures, lung-on-a-chip co-culture platforms) to support disease modeling and lung safety risk assessment.
  • Designing and executing experiments to characterize lung models, including evaluation of cell viability, morphology, and barrier integrity and function, using techniques such as cytotoxicity assays, confocal and high-content imaging, transepithelial resistance/permeability assays, and transcriptomic and proteomic analyses.
  • Collaborating closely with cross-functional teams within and outside the firm to align on complex model building with therapeutic strategies and program needs.
  • Analyzing, interpreting, and clearly communicating study results to collaborators and stakeholders, and contributing to internal and external scientific presentations as appropriate.
  • Maintaining comprehensive electronic documentation in accordance with departmental Standard Operating Procedures (SOPs) and contributing to study reports, safety assessments, and final deliverables.
Required Skills :
  • PhD in Bioengineering, Cell Biology, Molecular Biology, Toxicology (or related fields) with 0-5 years of experience post-PhD with hypothesis-driven research in industry or academia.
  • Experience in culturing multiple lung cell types, including relevant lung primary cells and cell lines.
  • Proven expertise in developing, qualifying, and applying airway or alveolar organoids, co-culture systems, and microphysiological or microfluidic platforms, to support drug discovery and translational research.
  • Proficiency with quantitative and qualitative characterization techniques such as qRT-PCR, RNA-seq, proteomics, immunofluorescence and confocal microscopy, live-cell and time-lapse imaging, high-content imaging/screening, and analysis of data generated from these assays.
  • Strong experimental design skills, with demonstrated ability in troubleshooting, method development, and protocol optimization for complex in vitro systems.
  • A collaborative, team-oriented scientist who prioritizes shared objectives and communicates effectively across disciplines, with a strong work ethic grounded in scientific rigor, attention to detail, and a commitment to excellence.
Preferred Skills :
  • Experience lung biology and immunology is a strong plus.
  • Advanced proficiency in MATLAB and/or Python for image processing, algorithm development, and large-scale data analysis.
SGA is a technology and resource solutions provider driven to stand out. We are a women-owned business. Our mission: to solve big IT problems with a more personal, boutique approach. Each year, we match consultants like you to more than 1,000 engagements. When we say let's work better together, we mean it. You'll join a diverse team built on these core values: customer service, employee development, and quality and integrity in everything we do. Be yourself, love what you do and find your passion at work. Please find us at .
SGA is an Equal Opportunity Employer and does not discriminate on the basis of Race, Color, Sex, Sexual Orientation, Gender Identity, Religion, National Origin, Disability, Veteran Status, Age, Marital Status, Pregnancy, Genetic Information, or Other Legally Protected Status. We are committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, and our services, programs, and activities. Please visit our company to request an accommodation or assistance regarding our policy.
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