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High Content Imaging Jobs (NOW HIRING)

LuckyJay Consulting

You will lead the design of a knowledge graph to link diverse data sources, including high-content imaging, sequencing (WGS, WTS, scRNA, and others), MOS model characteristics, clinical and disease ...

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High Content Imaging information

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$15

$38

$77

How much do high content imaging jobs pay per hour?

As of Jul 21, 2026, the average hourly pay for high content imaging in the United States is $38.91, according to ZipRecruiter salary data. Most workers in this role earn between $26.20 and $45.19 per hour, depending on experience, location, and employer.

What kind of jobs in media bring in $150,000 a year?

High Content Imaging roles in media or related fields typically do not reach $150,000 annually; however, senior positions such as media executives, creative directors, or specialized technical roles like imaging specialists with advanced skills and experience can earn this level or more. These roles often require extensive expertise, leadership, and sometimes advanced certifications or degrees.

What are the key skills and qualifications needed to thrive as a High Content Imaging Specialist, and why are they important?

To thrive as a High Content Imaging Specialist, expertise in cell biology, image analysis, and microscopy, often with an advanced degree in a life science field, is essential. Familiarity with high-throughput imaging platforms (such as PerkinElmer Opera Phenix or Molecular Devices ImageXpress), image analysis software (like CellProfiler or ImageJ), and data management systems is typically required. Strong problem-solving skills, attention to detail, and effective communication are crucial for optimizing assays and collaborating with cross-functional teams. These competencies ensure accurate data acquisition, reliable experimental results, and successful integration of imaging technologies in research workflows.

What are some common challenges faced by professionals working in High Content Imaging, and how can they be addressed?

Professionals in High Content Imaging often encounter challenges such as managing large volumes of data, ensuring image quality and consistency, and troubleshooting complex imaging equipment. These challenges can be addressed by developing strong data management skills, staying current with image analysis software, and collaborating closely with IT and instrument support teams. Additionally, regular training on new technologies and maintaining clear documentation can help ensure smooth workflows and minimize downtime.

What is high content imaging?

High content imaging is an advanced microscopy technique used primarily in biological and pharmaceutical research to capture and analyze large volumes of complex cellular data. It combines high-resolution imaging with automated data analysis to assess multiple cellular features simultaneously, making it a powerful tool for drug discovery, toxicity testing, and cell biology studies. This approach enables researchers to gather quantitative information from thousands of cells in a single experiment, increasing efficiency and data quality. High content imaging often uses fluorescence labeling and sophisticated software to extract meaningful biological insights from images.

What is the difference between High Content Imaging vs Cell Imaging Specialist?

AspectHigh Content ImagingCell Imaging Specialist
Required CredentialsBachelor's or higher in biology, biochemistry, or related fields; experience with microscopy and imaging softwareSimilar credentials; often includes microscopy and cell biology expertise
Work EnvironmentResearch labs, pharmaceutical companies, biotech firmsLaboratories focusing on cell analysis, drug discovery, or biomedical research
Industry UsageUsed across biotech, pharma, academic researchPrimarily in research and development settings within biotech and pharma
Common Search/ComparisonHigh Content Imaging vs Cell Imaging Specialist

High Content Imaging involves automated microscopy and image analysis to study cellular responses on a large scale, often used in drug screening. Cell Imaging Specialist focuses on detailed microscopy of cells, emphasizing manual or semi-automated imaging techniques. While both roles require microscopy skills and biological knowledge, High Content Imaging emphasizes high-throughput analysis, whereas Cell Imaging Specialists focus on detailed cellular visualization.

What are some careers that use microscopes?

Careers that use microscopes include high content imaging specialists, microbiologists, pathologists, and laboratory technicians. These roles often require knowledge of microscopy techniques, attention to detail, and proficiency with imaging equipment to analyze biological or material samples accurately.

What jobs in the US pay 300,000 a year?

High Content Imaging specialists typically do not earn $300,000 annually; such salaries are more common in executive, medical, or specialized technical roles. Positions like senior scientists, medical directors, or biotech executives in related fields may reach or exceed this level with experience and advanced skills. Salary levels depend on industry, location, and level of responsibility.

What imaging job pays the most?

High Content Imaging specialists or roles involving advanced microscopy and image analysis tend to have higher salaries within imaging jobs, especially when combined with skills in data analysis, software proficiency, and scientific research. Senior positions, such as imaging managers or specialists with extensive experience and certifications, generally earn the highest pay in this field.
More about High Content Imaging jobs
What cities are hiring for High Content Imaging jobs? Cities with the most High Content Imaging job openings:
What states have the most High Content Imaging jobs? States with the most job openings for High Content Imaging jobs include:
What job categories do people searching High Content Imaging jobs look for? The top searched job categories for High Content Imaging jobs are:
High Content Imaging jobs near you
Senior Scientist, Biology

Senior Scientist, Biology

Flagship Pioneering, Inc.

Cambridge, MA

$100K - $136K/yr

Other

Medical, Retirement

Re-posted 9 days ago

Job description

Company Summary

FL106 Inc. is a privately held, early-stage biotechnology company focused on developing novel drug delivery modalities. FL106 is backed by Flagship Pioneering, which provides the strategic vision and resources to advance FL106 from platform validation to clinical impact.

Position Summary

We are seeking a highly motivated and experienced Senior Scientist to join our research team. The successful candidate will possess deep expertise in cell isolation and sorting, in vivo/ in vitro mouse studies, gene-silencing technologies (siRNA), flow cytometry and advanced microscopy techniques. This individual will play a key role in designing, executing, and interpreting preclinical studies to therapeutic programs. Depending on experience and demonstrated leadership, the candidate may lead research initiatives, mentor team members, manage external collaborations, and contribute to scientific and program strategy.

Key Responsibilities

  • Design, execute, and analyze complex in vitro and ex vivo experiments to support discovery and preclinical research programs.
  • Lead and perform multi-parameter flow cytometry assays, including panel design, optimization, troubleshooting, and data interpretation.
  • Perform and optimize cell isolation and cell sorting (e.g., FACS, MACS) from various tissues and biological samples.
  • Execute in vivo mouse studies, including disease model development, dosing, tissue collection, and phenotypic characterization.
  • Develop and apply siRNA-based approaches for target validation, pathway interrogation, and mechanistic studies.
  • Design and perform microscopy-based experiments, including fluorescence, confocal, live-cell, and high-content imaging, and analyze imaging datasets.
  • Utilize complementary molecular and cellular biology techniques to support target validation and mechanism-of-action studies.
  • Design, analyze, and interpret cell profiling experiments using flow cytometry, imaging, and molecular approaches.
  • Contribute to biomarker discovery, translational research efforts, and preclinical candidate characterization.
  • Analyze, interpret, and present experimental findings to cross-functional teams and senior leadership.
  • Generate technical reports, presentations, study summaries, and scientific documentation to support program advancement.
  • Collaborate effectively with internal teams, CROs, academic collaborators, and external partners.
  • Mentor junior scientists and contribute to a collaborative, innovative research environment.
  • For Senior Scientist and Principal Scientist levels, provide scientific leadership, contribute to research strategy, and lead cross-functional initiatives.
  • Maintain accurate experimental records and ensure compliance with institutional, ethical, and regulatory guidelines.

Qualifications

  • Ph.D. in Cell Biology, Genetics, Molecular Biology, Pharmacology, Immunology, Biomedical Sciences, or a related field with 6+ years of relevant experience for Senior Scientist roles; 8+ years of industry experience and demonstrated scientific leadership for Principal Scientist roles.
  • Alternatively, an M.S. degree with substantial relevant industry experience.
  • Strong expertise in flow cytometry, including cell sorting (FACS), panel design, troubleshooting, and data analysis using FlowJo or equivalent software.
  • Hands-on experience with cell isolation techniques, including tissue dissociation and magnetic bead-based separation.
  • Extensive experience with mouse models and in vitro experimental techniques.
  • Demonstrated expertise in siRNA design, delivery, optimization, and functional validation.
  • Hands-on experience with microscopy platforms, including fluorescence, confocal, live-cell, and high-content imaging systems.
  • Strong quantitative data analysis, experimental design, and statistical analysis skills.
  • Excellent communication, presentation, and scientific writing skills.
  • Ability to work independently and collaboratively in a fast-paced, multidisciplinary environment.

Preferred Qualifications

  • Experience in translational research, drug discovery, or preclinical therapeutic development.
  • Experience in biotechnology or pharmaceutical industry settings.
  • Experience with cell profiling, phenotyping, and functional assays using primary mouse and human cells, as well as established cell lines.
  • Experience with single-cell and/or spatial biology technologies, including scRNA-seq, CITE-seq, or spatial transcriptomics.
  • Experience managing CROs, external collaborators, and cross-functional project teams.
  • Proficiency with additional molecular and cellular biology techniques, including:
    • qPCR
    • Western blotting
    • ELISA and multiplex cytokine assays
    • RNA-seq and transcriptomic analysis
    • Gene silencing and gene-editing approaches
    • Protein overexpression systems
    • Immunohistochemistry (IHC), immunofluorescence (IF), and advanced flow cytometry applications
  • Experience with image analysis software such as ImageJ/Fiji, CellProfiler, Imaris, or equivalent platforms.
  • Experience with computational analysis of flow cytometry, imaging, or transcriptomic datasets.
  • Track record of scientific publications, patents, and/or successful advancement of therapeutic programs.

About Flagship

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in generation of over 500 patents, initiation of over 50 clinical trials for novel therapeutic agents and an aggregate value of more than $90 billion. Many of the companies Flagship has founded have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

Flagship Pioneering is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, "FSP") do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com. 

The salary range for this role is $126,000 - $160,000. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. FL106 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL106's good faith estimate as of the date of publication and may be modified in the future.

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