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High Content Imaging Jobs in California (NOW HIRING)

Arcadia Science

Imaging Specialist

Emeryville, CA · On-site

The core is built to enable high-content imaging of diverse organisms -- from 2 to 250 µm, on timescales from milliseconds to hours -- using both label-free and reporter-based approaches. Our ...

Transcripta Bio

Scientist, Drug Discovery

Palo Alto, CA · On-site

$120 - $180/hr

Design and conduct downstream validation experiments to confirm screening hits and interrogate drug mechanisms of action, utilizing high-content imaging, qPCR, immunocytochemistry, Western blot ...

insitro

Associate Scientist III

South San Francisco, CA · On-site

$125.28 - $129/hr

Developing confocal imaging experiments that result in high-content imaging data and perform in-house image analyses for assay characterization; In time metadata registration and maintaining thorough ...

Transcripta Bio

Computational Biologist

Palo Alto, CA · On-site

... high-content imaging data. * Analyze data from drug perturbation screens to identify transcriptomic signatures, compound-gene associations, and patterns of drug response across disease-relevant cell ...

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All JobsHigh Content Imaging JobsHigh Content Imaging Jobs in California

High Content Imaging information

See California salary details

$14

$38

$76

How much do high content imaging jobs pay per hour?

As of Aug 26, 2026, the average hourly pay for high content imaging in California is $38.40, according to ZipRecruiter salary data. Most workers in this role earn between $25.87 and $44.62 per hour, depending on experience, location, and employer.

What is high content imaging?

High content imaging is an advanced microscopy technique used primarily in biological and pharmaceutical research to capture and analyze large volumes of complex cellular data. It combines high-resolution imaging with automated data analysis to assess multiple cellular features simultaneously, making it a powerful tool for drug discovery, toxicity testing, and cell biology studies. This approach enables researchers to gather quantitative information from thousands of cells in a single experiment, increasing efficiency and data quality. High content imaging often uses fluorescence labeling and sophisticated software to extract meaningful biological insights from images.

What are the key skills and qualifications needed to thrive as a high content imaging specialist?

To thrive as a High Content Imaging Specialist, expertise in cell biology, image analysis, and microscopy, often with an advanced degree in a life science field, is essential. Familiarity with high-throughput imaging platforms (such as PerkinElmer Opera Phenix or Molecular Devices ImageXpress), image analysis software (like CellProfiler or ImageJ), and data management systems is typically required. Strong problem-solving skills, attention to detail, and effective communication are crucial for optimizing assays and collaborating with cross-functional teams. These competencies ensure accurate data acquisition, reliable experimental results, and successful integration of imaging technologies in research workflows.

What are some common challenges faced by professionals working in high content imaging, and how can they be addressed?

Professionals in High Content Imaging often encounter challenges such as managing large volumes of data, ensuring image quality and consistency, and troubleshooting complex imaging equipment. These challenges can be addressed by developing strong data management skills, staying current with image analysis software, and collaborating closely with IT and instrument support teams. Additionally, regular training on new technologies and maintaining clear documentation can help ensure smooth workflows and minimize downtime.

What is the difference between High Content Imaging vs Cell Imaging Specialist?

AspectHigh Content ImagingCell Imaging Specialist
Required CredentialsBachelor's or higher in biology, biochemistry, or related fields; experience with microscopy and imaging softwareSimilar credentials; often includes microscopy and cell biology expertise
Work EnvironmentResearch labs, pharmaceutical companies, biotech firmsLaboratories focusing on cell analysis, drug discovery, or biomedical research
Industry UsageUsed across biotech, pharma, academic researchPrimarily in research and development settings within biotech and pharma
Common Search/ComparisonHigh Content Imaging vs Cell Imaging Specialist

High Content Imaging involves automated microscopy and image analysis to study cellular responses on a large scale, often used in drug screening. Cell Imaging Specialist focuses on detailed microscopy of cells, emphasizing manual or semi-automated imaging techniques. While both roles require microscopy skills and biological knowledge, High Content Imaging emphasizes high-throughput analysis, whereas Cell Imaging Specialists focus on detailed cellular visualization.

What are popular job titles related to High Content Imaging jobs in California?

For High Content Imaging jobs in California, the most frequently searched job titles are:

What job categories do people searching High Content Imaging jobs in California look for?

The top searched job categories for High Content Imaging jobs in California are:

High Content Imaging jobs near you
Infographic showing various High Content Imaging job openings in California as of August 2026, with employment types broken down into 1% As Needed, 77% Full Time, 18% Part Time, and 4% Contract. Highlights an 86% Physical, 1% Hybrid, and 13% Remote job distribution, with an average salary of $79,873 per year, or $38.4 per hour.

SRA 1/2

University of California San Francisco

San Francisco, CA • On-site

Full-time

Posted 25 days ago

University Of California San Francisco rating

7.8

Company rating: 7.8 out of 10

Based on 13 frontline employees who took The Breakroom Quiz

233rd of 623 rated colleges and universities

Job description

Please note: this is a temporary assignment (5 months). 

The Institute for Neurodegenerative Diseases (IND) at UCSF is looking for a Staff Research Associate (SRA) to join the High Throughput Screening (HTS) group. In this role, you will be part of the HTS group, charged with screening novel chemical libraries and biologicals using cell-based high content imaging (HCI) assays, to identify candidate small molecule therapeutics for treating diverse neurodegenerative diseases such as Parkinson's Disease. The primary responsibilities of this position are to execute end-point imaging assays, conduct quantitative analyses and generate consumable data. This position includes hands-on lab work, especially operating and maintaining automation, high-content imaging of cells, analyses and uploading imaging data, cell culture, and helping the team with running cell-based and biochemical drug screening assays. Additionally, the candidate will be required to perform appropriate experimental planning, data analysis, documentation of results and supply management required to complete all aspects of the experimental work.

Working hours:

12 pm to 8:30 pm on-site work hours on 4 weekdays (Mon, Tues or Wed, Thur, and Fri), and 

9:00 am to 5:00 pm on 1 weekend day (Sat or Sun) 

SRA 1:

  • B.S. in Biology, Cell Biology, Biochemistry or related science 
  • Mammalian cell culture experience
  • Hands on molecular biology experience
  • Western blot analysis
  • Excellent oral and written communication skills 
  • Organized 
  • Excellent record keeping skills.
  • Ability to work independently and as part of a team
  • Enthusiasm, positive outlook and scientific curiosity.

SRA 2: In addition to the above,

  • Minimum 1 year experience in a research laboratory environment following degree completion

Preferred Qualifications

  • M.S. in Biology, Cell Biology, Biochemistry or related science
  • BSL 2/3 approved (Bio Secure Lab)
  • Experience with high content imaging and image analysis
  • Experience with robotic liquid handling equipment
  • Some knowledge of neurodegenerative disease research 
  • 3 years experience in a research laboratory environment following degree completion
  • Operate and maintain automated laboratory equipment
  • High content image analysis
  • Data analyses 
  • Formatting and uploading data
  • Maintain human cell lines

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