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High Content Imaging Jobs (NOW HIRING)

Senior Research Scientist I

Cambridge, MA · On-site

$115K - $161K/yr

We use systematic approaches in genomics, biology, high content imaging, chemistry, and machine learning coupled with the Broad's culture of creativity, risk taking, and open sharing, to successfully ...

The core is built to enable high-content imaging of diverse organisms -- from 2 to 250 µm, on timescales from milliseconds to hours -- using both label-free and reporter-based approaches. Our ...

The core is built to enable high-content imaging of diverse organisms - from 2 to 250 m, on timescales from milliseconds to hours - using both label-free and reporter-based approaches. Our current ...

The core is built to enable high-content imaging of diverse organisms - from 2 to 250 µm, on timescales from milliseconds to hours - using both label-free and reporter-based approaches. Our current ...

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High Content Imaging information

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$15

$38

$77

How much do high content imaging jobs pay per hour?

As of Jul 20, 2026, the average hourly pay for high content imaging in the United States is $38.91, according to ZipRecruiter salary data. Most workers in this role earn between $26.20 and $45.19 per hour, depending on experience, location, and employer.

What kind of jobs in media bring in $150,000 a year?

High Content Imaging roles in media or related fields typically do not reach $150,000 annually; however, senior positions such as media executives, creative directors, or specialized technical roles like imaging specialists with advanced skills and experience can earn this level or more. These roles often require extensive expertise, leadership, and sometimes advanced certifications or degrees.

What are the key skills and qualifications needed to thrive as a High Content Imaging Specialist, and why are they important?

To thrive as a High Content Imaging Specialist, expertise in cell biology, image analysis, and microscopy, often with an advanced degree in a life science field, is essential. Familiarity with high-throughput imaging platforms (such as PerkinElmer Opera Phenix or Molecular Devices ImageXpress), image analysis software (like CellProfiler or ImageJ), and data management systems is typically required. Strong problem-solving skills, attention to detail, and effective communication are crucial for optimizing assays and collaborating with cross-functional teams. These competencies ensure accurate data acquisition, reliable experimental results, and successful integration of imaging technologies in research workflows.

What are some common challenges faced by professionals working in High Content Imaging, and how can they be addressed?

Professionals in High Content Imaging often encounter challenges such as managing large volumes of data, ensuring image quality and consistency, and troubleshooting complex imaging equipment. These challenges can be addressed by developing strong data management skills, staying current with image analysis software, and collaborating closely with IT and instrument support teams. Additionally, regular training on new technologies and maintaining clear documentation can help ensure smooth workflows and minimize downtime.

What is high content imaging?

High content imaging is an advanced microscopy technique used primarily in biological and pharmaceutical research to capture and analyze large volumes of complex cellular data. It combines high-resolution imaging with automated data analysis to assess multiple cellular features simultaneously, making it a powerful tool for drug discovery, toxicity testing, and cell biology studies. This approach enables researchers to gather quantitative information from thousands of cells in a single experiment, increasing efficiency and data quality. High content imaging often uses fluorescence labeling and sophisticated software to extract meaningful biological insights from images.

What is the difference between High Content Imaging vs Cell Imaging Specialist?

AspectHigh Content ImagingCell Imaging Specialist
Required CredentialsBachelor's or higher in biology, biochemistry, or related fields; experience with microscopy and imaging softwareSimilar credentials; often includes microscopy and cell biology expertise
Work EnvironmentResearch labs, pharmaceutical companies, biotech firmsLaboratories focusing on cell analysis, drug discovery, or biomedical research
Industry UsageUsed across biotech, pharma, academic researchPrimarily in research and development settings within biotech and pharma
Common Search/ComparisonHigh Content Imaging vs Cell Imaging Specialist

High Content Imaging involves automated microscopy and image analysis to study cellular responses on a large scale, often used in drug screening. Cell Imaging Specialist focuses on detailed microscopy of cells, emphasizing manual or semi-automated imaging techniques. While both roles require microscopy skills and biological knowledge, High Content Imaging emphasizes high-throughput analysis, whereas Cell Imaging Specialists focus on detailed cellular visualization.

What are some careers that use microscopes?

Careers that use microscopes include high content imaging specialists, microbiologists, pathologists, and laboratory technicians. These roles often require knowledge of microscopy techniques, attention to detail, and proficiency with imaging equipment to analyze biological or material samples accurately.

What jobs in the US pay 300,000 a year?

High Content Imaging specialists typically do not earn $300,000 annually; such salaries are more common in executive, medical, or specialized technical roles. Positions like senior scientists, medical directors, or biotech executives in related fields may reach or exceed this level with experience and advanced skills. Salary levels depend on industry, location, and level of responsibility.

What imaging job pays the most?

High Content Imaging specialists or roles involving advanced microscopy and image analysis tend to have higher salaries within imaging jobs, especially when combined with skills in data analysis, software proficiency, and scientific research. Senior positions, such as imaging managers or specialists with extensive experience and certifications, generally earn the highest pay in this field.
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What states have the most High Content Imaging jobs? States with the most job openings for High Content Imaging jobs include:
What job categories do people searching High Content Imaging jobs look for? The top searched job categories for High Content Imaging jobs are:

Principal Scientist, High-Content Imaging

Jj

Spring House, PA

Full-time

Posted 12 days ago


Job description

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at jnj.com.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biological Research

Job Category:

Scientific/Technology

All Job Posting Locations:

Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine:
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more athttps://www.jnj.com/innovative-medicine

We are searching for the best talent for a Principal Scientist, High-Content Imaging role as part of Mechanistic & Cellular Pharmacology located in Spring House, PA.

Purpose:

The ideal candidate will be a hands-on technical contributor responsible for developing, validating, and deploying cutting-edge high-content imaging capabilities to advance therapeutic discovery across the Immunology, Neuroscience, and Oncology portfolios.

The principal scientist will design and execute end-to-end imaging workflows across diverse 2D and 3D cell models and tissues. This role will focus on the development and execution of novel molecular assays, establishing and optimizing laboratory workflows and infrastructure, and executing technical work across multiple imaging and assay platforms. Additional responsibilities include building and implementing data generation pipelines, troubleshooting complex experiments at the bench and across imaging platforms, optimizing protocols, analyzing imaging data, and collaborating with internal teams, CROs, and external technology partners to support capability development.

Ideal candidates bring deep hands-on experience in high-content imaging, particularly within disease-relevant biological contexts, along with strong experimental, assay development, and computational image analysis skills. Familiarity with state-of-the-art image analysis methods, including AI/ML-enabled approaches, and enthusiasm for applying these tools in day-to-day experimental workflows are also required.

You will be responsible for:

  • Applying state-of-the-art drug discovery approaches in a multidisciplinary team!
  • Developing, optimizing, andvalidating complex high-content imaging and other high-dimensional assays to support Immunology, Neuroscience, and Oncology programs.
  • Establishing and refiningnew molecular assays, including troubleshooting, workflow development, and technical feasibility assessments.
  • Collaborating closely with colleagues and therapeutic area teams to translate high-dimensional readouts intoactionable biological insights.
  • Working closely with CROs and/or external partners, ensuring highquality data generation, timeline alignment, and technical deliverables.
  • Contributing to data workflows by supporting data mapping, QC frameworks, and analytical handoffsto computational teams.

Qualifications

  • Education:
    • Minimum of a Ph.D. in Biochemistry, Systems biology, Human biology or a related discipline is required.

Required:

  • A minimum of 4 years of pharmaceutical industry experience is required.
  • Strong track record of high-impact scientific deliverables as evidenced by publications, presentations, and recognition within the scientific community.
  • Deep, technical high-content imaging expertise is required, including understanding of end-to-end workflows, method limitations, and mitigation strategies.
  • Excellent written communication, verbal communication, and oral presentation skills are required.
  • Demonstrated ability to work across disciplines and functional areas is required.
  • Ability to apply novel approaches to address complex biology questions, as evidenced through strong peer-reviewed publications, is required.
  • Experience as a problem solver, and team collaborator able to facilitate understanding between biologists and data scientists is required.

Preferred:

  • Expertise in complex cell models and/or tissue imaging is preferred.
  • Experience working with and/or guiding external collaborators in industry or academia is preferred.
  • Experience integrating different types of high-dimensional data is preferred.
  • Proficiency in programming languages such as R or Python, and/or experience with agentic AI to deliver high-quality analysis code, is preferred.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.

#LI-Onsite

Required Skills:

Preferred Skills:

Big Data Management, Critical Thinking, Data Reporting, Data Savvy, Drug Discovery Development, Molecular Diagnostics, Organizing, Pharmaceutical Microbiology, Problem Solving, Product Knowledge, Project Reporting, Project Schedule, Research Proposals, Scientific Research, Standard Operating Procedure (SOP), Standard Scientific Processes and Procedures, Strategic Thinking, Sustainability