Gxp Systems Jobs (NOW HIRING)

Job Summary:
Moderna is a leading biopharmaceutical company focused on mRNA technology. The GxP Endpoint Engineer will be responsible for managing the SCCM environment to support GxP operations, ensuring compliance with quality assurance standards and maintaining a validated infrastructure.
Responsibilities:
• Own and manage the SCCM GxP environment, ensuring all configurations, task sequences, and deployments comply with QA guidance and validation standards.
• Design, document, and maintain standard operating procedures (SOPs) and configuration baselines specific to GxP systems.
• Implement and monitor strict QC processes for all deployments, including peer review, QA validation, and change control sign-off prior to production release.
• Oversee all operating system deployments and in-place upgrades (IPU) for validated systems, ensuring consistent execution under GxP change control.
• Manage patching cycles, including Microsoft and third-party updates, coordinating with QA, GxP Support, and Application Owners to plan, validate, and document each phase.
• Create and maintain deployment and compliance reports, providing transparency to QA and management on patch and configuration status across the GxP fleet.
• Collaborate with Application Owners and GxP Support teams to coordinate deployments, validate installations, and resolve environment-specific issues.
• Develop and publish Knowledge Base (KB) articles and operational guides for support teams and end users related to SCCM processes, patching, and imaging.
• Serve as the escalation point for packaging, deployment, and compliance failures impacting GxP systems.
• Partner with QA to participate in audits, provide system validation evidence, and ensure documentation accuracy across all controlled activities.
• Contribute to the ongoing evolution of how SCCM operates in Moderna’s validated environment, helping to design scalable, compliant frameworks for automation and reporting.
Qualifications:
Required:
• 6+ years of experience in SCCM/MECM administration, including task sequences, OSD, collections, compliance baselines, and application deployments.
• Proven experience managing systems in regulated (GxP, GMP, or validated) environments, adhering to QA and change control processes.
• Strong understanding of QA, QC, and validation principles within endpoint management.
• Experience performing in-place upgrades (IPUs), PXE imaging, and patch management in controlled environments.
• Hands-on experience with third-party patching tools and their integration with SCCM.
• Familiarity with ServiceNow for change control, approval workflows, and incident tracking.
• Ability to produce comprehensive documentation, SOPs, and KBs aligned with GxP validation standards.
• Strong collaboration skills to engage with QA, Application Owners, and Support teams on validation, testing, and incident management.
Preferred:
• Analytical mindset and attention to detail to ensure every configuration and deployment meets compliance and performance expectations.
• Bachelor’s degree in Information Technology, Computer Science, or a related technical discipline.
• Experience with co-managed SCCM + Intune environments in validated systems.
• Familiarity with JAMF Pro for cross-platform GxP compliance awareness.
• Knowledge of GAMP 5 validation principles or equivalent regulated system frameworks.
• Prior experience generating QA audit documentation or participating in validation testing for endpoint systems.
• Understanding of Windows OS lifecycle management and modern endpoint management best practices.
• Certifications such as Microsoft Endpoint Manager, ITIL, or CompTIA Security+.
• A proactive, methodical approach to process improvement and compliance-driven automation.
Company:
Moderna Therapeutics is a biotechnology company that develops medicines and vaccines based on messenger RNA (mRNA) technology. Founded in 2010, the company is headquartered in Cambridge, USA, with a team of 1001-5000 employees. The company is currently Late Stage.