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Etmf Jobs (NOW HIRING)

ICON

Clinical Trial Assistant

San Francisco, CA · On-site

$56K - $70K/yr

Lead the setup of electronic Trial Master File (eTMF) system and clinical trial management (CTMS). Ensure information is updated during the study per ICH/GCP and sponsor SOP's * Create and maintain ...

CSL

Senior TMF Lead

King Of Prussia, PA · On-site

TMF Systems & Innovation - Oversee TMF technologies, eTMF enhancements, reference model updates, templates, tools, training, and continuous improvement initiatives aligned with industry best ...

Arthrex

Clinical Study Manager

Naples, FL · On-site

Ensures compliance with the Clinical Trial Management System (CTMS), Electronic Trial Master (eTMF) filing, and Electronic Data Capture (EDC) systems, securing essential documents and quality ...

Icon plc

Clinical Trial Assistant

San Francisco, CA · Hybrid

$56K - $70K/yr

Lead the setup of electronic Trial Master File (eTMF) system and clinical trial management (CTMS). Ensure information is updated during the study per ICH/GCP and sponsor SOP's * Create and maintain ...

Icon plc

Clinical Trial Assistant

San Francisco, CA · Hybrid

$56K - $70K/yr

Lead the setup of electronic Trial Master File (eTMF) system and clinical trial management (CTMS). Ensure information is updated during the study per ICH/GCP and sponsor SOP's * Create and maintain ...

ARTHREX

Clinical Study Manager

Naples, FL · On-site

Ensures compliance with the Clinical Trial Management System (CTMS), Electronic Trial Master (eTMF) filing, and Electronic Data Capture (EDC) systems, securing essential documents and quality ...

CSL

Senior TMF Lead

King Of Prussia, PA · Hybrid

TMF Systems & Innovation - Oversee TMF technologies, eTMF enhancements, reference model updates, templates, tools, training, and continuous improvement initiatives aligned with industry best ...

IPolarity LLC

Program Manager

Whippany, NJ · On-site

$65 - $70/hr

Life Sciences R&D GxP experienced Global Program Manager (for client's program scope) with experience in successfully program managing a Veeva Vault Clinical (CTMS, Site Connect preferred else eTMF ...

CSL

Senior TMF Lead

King Of Prussia, PA · On-site

TMF Systems & Innovation - Oversee TMF technologies, eTMF enhancements, reference model updates, templates, tools, training, and continuous improvement initiatives aligned with industry best ...

Ocugen Inc

TMF Lead

Malvern, PA · On-site

$32.75 - $45/hr

Configure and administer the Veeva Vault eTMF system for assigned studies, including user access/role management, metadata and document classification, workflow configuration, and support for system ...

CSL

Senior TMF Lead

King Of Prussia, PA · On-site

TMF Systems & Innovation - Oversee TMF technologies, eTMF enhancements, reference model updates, templates, tools, training, and continuous improvement initiatives aligned with industry best ...

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Etmf information

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$34.5K

$96.2K

$130.5K

How much do etmf jobs pay per year?

As of Aug 16, 2026, the average yearly pay for etmf in the United States is $96,238.00, according to ZipRecruiter salary data. Most workers in this role earn between $86,000.00 and $109,500.00 per year, depending on experience, location, and employer.

What are the typical daily responsibilities of an eTMF specialist?

As an eTMF Specialist, your daily responsibilities include managing, organizing, and maintaining essential clinical trial documents within the electronic Trial Master File system. You will monitor document completeness, track filing timelines, and ensure regulatory compliance, often collaborating with clinical, regulatory, and quality assurance teams. Regular audits, resolving document discrepancies, and training other team members on eTMF processes are also common tasks. The role requires staying up to date with changing regulatory requirements and maintaining clear communication with multiple stakeholders to support successful clinical trial operations.

What is an eTMF?

An eTMF (electronic Trial Master File) job involves managing and maintaining digital documentation related to clinical trials. Professionals in this role ensure regulatory compliance, organize essential trial documents, and support inspection readiness. They may use eTMF systems to track, classify, and archive trial-related files. Strong attention to detail and knowledge of clinical research regulations are essential.

What are the key skills and qualifications needed to thrive in the eTMF position, and why are they important?

To thrive as an eTMF (electronic Trial Master File) Specialist, you need a strong understanding of clinical trial documentation, regulatory requirements, and document management best practices, often supported by a degree in life sciences or a related field. Familiarity with eTMF systems such as Veeva Vault or Medidata, as well as relevant certifications like the DIA TMF Certificate, is highly beneficial. Attention to detail, excellent organizational skills, and effective cross-functional communication make candidates stand out in this role. These competencies are crucial for ensuring that clinical trial documentation is complete, inspection-ready, and compliant with industry regulations.

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Etmf jobs near you
Infographic showing various Etmf job openings in the United States as of August 2026, with employment types broken down into 92% Full Time, 1% Part Time, and 7% Contract. Highlights an 75% Physical, 6% Hybrid, and 19% Remote job distribution, with an average salary of $96,238 per year, or $46.3 per hour.

Clinical Trial Assistant

ICON

San Francisco, CA • On-site

$56K - $70K/yr

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 5 days ago

Job description

Clinical Trial Assistant (San Francisco, CA)
ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.
As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.
What you will be doing:
The Clinical Trial Assistant is a member of the clinical trial team supporting delivery of clinical studies within the sponsor. The CTA will support the study team to ensure the operational deliveries are executed then the expected timeline, approved budget, and at high quality from protocol development through study setup, maintenance, close out and study archiving.
  • The CTA supports the study team in delegated activities and provides technical, administrative and logistical support to ensure efficient execution of clinical trials in line with ICH/GCP sponsor SOP's and regulatory regulations.
  • Lead the setup of electronic Trial Master File (eTMF) system and clinical trial management (CTMS). Ensure information is updated during the study per ICH/GCP and sponsor SOP's
  • Create and maintain communication platforms (i.e. MS Teams, SPOL, group e-mail list) for the study team
  • Control systems access for assigned studies but not limited to IxRS, EDC, CT's, and eTMF
  • Support clinical trial registration and disclosure on websites per applicable regulatory requirements
  • Responsible for overall TMF status. Guide study team members on the eTMF/paper TMF document transfer and archival. Lead the quality check (QC) per the TMF plan. Help draft TMF plan
  • Facilitate finance related activities such as sign off, IO and PO setup, processing invoices, track accruals and budget for maintenance and reconciliation for sites and third-party vendors
  • Support oversight of monitoring visit report review. Activities include updating MVR trackers and overseeing MVR review metrics
  • May support data oversight and reconciliation efforts vendor systems, SAEs, protocol deviations and more as needed per study
  • Coordination and tracking of clinical supplies
  • Coordinate and arrange internal and external meetings, including but not to study team meetings, vendor defense meetings, investigator meetings, and committee review meeting take meeting minutes as needed.
  • Compile and maintain the clinical trial related lists and logs, including but not limited to study document version tracker, decision risk log, contact list, Q&A log, vendor list, and specific training log.
  • Draft and distribute newsletters communications Asia materials to internal and external stakeholders
  • Complete delegated tasks during audit and inspection by regulatory authorities

What you need to have:
  • High school or GED with four years relevant experience. Bachelor's degree or above (Life Sciences preferred) or certification in a related health profession (i.e. nursing, medical or laboratory technology) from an accredited institution is preferred.
  • At least 1 year experience as a CTA, CRC, or other role in clinical trials.
  • Oncology experience a huge plus!
  • Proven organizational and presentation skills
  • Ability to manage multiple tasks with meticulous attention to detail
  • Quick learner and team player
  • Excellent written and verbal communication skills
  • Computer proficiency in Microsoft Word, Excel, PowerPoint and Outlook
  • Good knowledge of the ICH/GCP
  • Position is on site 3-4 days a week at client office in South San Francisco, CA and days from home.

Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
Rewards & Benefits
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.
Salary Range
$56,704.00-$70,880.00
Are you a current ICON Employee? Please click here to apply

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