Professionals in an EPMO are responsible for developing and overseeing enterprise-wide project management standards, ensuring that all projects align with organizational strategy and objectives. They typically establish governance frameworks, provide guidance and support to project managers, monitor project portfolios, and analyze risks and performance metrics. Collaboration with senior leaders, business units, and cross-functional teams is a key part of the role, as is facilitating communication and decision-making across the organization. These responsibilities help drive consistency, accountability, and strategic outcomes in project execution.