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Enzyme Engineering Jobs (NOW HIRING)

Codexis

Supply Chain Manager

Redwood City, CA · On-site

Codexis is a leading enzyme engineering company leveraging its proprietary CodeEvolver technology platform to discover, develop and enhance novel, high-performance enzymes and other classes of ...

Codexis Inc

Supply Chain Manager

Plano, TX · On-site

$150K - $165K/yr

Codexis is a leading enzyme engineering company leveraging its proprietary CodeEvolver ® technology platform to discover, develop and enhance novel, high-performance enzymes and other classes of ...

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$82.5K

$172.5K

How much do enzyme engineering jobs pay per year?

As of May 28, 2026, the average yearly pay for enzyme engineering in the United States is $82,530.00, according to ZipRecruiter salary data. Most workers in this role earn between $54,000.00 and $100,000.00 per year, depending on experience, location, and employer.

What is an Enzyme Engineering job?

An Enzyme Engineering job involves designing, modifying, and optimizing enzymes for industrial, medical, or research applications. Professionals in this field use biochemical, genetic, and computational techniques to enhance enzyme performance, stability, or specificity. They work in industries such as pharmaceuticals, biofuels, food processing, and environmental science to develop more efficient and sustainable biological solutions.

What are the key skills and qualifications needed to thrive in the Enzyme Engineering position, and why are they important?

To excel in Enzyme Engineering, candidates typically need a strong background in biochemistry, molecular biology, and chemical engineering, often supported by an advanced degree. Familiarity with techniques such as protein expression, directed evolution, enzyme assays, and tools like PCR, chromatography systems, and computational modeling software is important, as are certifications in laboratory safety. Strong analytical thinking, problem-solving, and communication skills enable effective collaboration and innovation in research teams. These abilities are crucial for developing novel enzymes and optimizing biocatalysts for industrial, pharmaceutical, or environmental applications.

What are the typical daily responsibilities of someone working in enzyme engineering?

In enzyme engineering, daily tasks often include designing and performing experiments to modify or improve enzyme function, analyzing data using biochemical and computational tools, and documenting research findings. Professionals regularly work with interdisciplinary teams, including chemists, biologists, and process engineers, to advance project goals and troubleshoot technical challenges. Managing laboratory equipment, ensuring compliance with safety protocols, and sometimes contributing to patent filings or journal publications are also common. This blend of hands-on lab work and collaborative problem-solving offers a dynamic and intellectually stimulating work environment.
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Enzyme Engineering jobs near you
Infographic showing various Enzyme Engineering job openings in the United States as of May 2026, with employment types broken down into 77% Full Time, and 23% Contract. Highlights an 92% In-person, and 8% Remote job distribution, with an average salary of $82,530 per year, or $39.7 per hour.
Scientist, Enzyme Engineering

Scientist, Enzyme Engineering

Bluestem Biosciences

Omaha, NE • On-site

Full-time

Posted 4 hours ago

Job description

Scientist, Enzyme Engineering

OMAHA, NE


ABOUT US:
We use American corn and existing bioethanol infrastructure to produce critical chemicals right here at homepowering U.S. competitiveness and securing our nation's supply chains - while reinvesting in agricultural America. Bluestem Biosciences has engineered a breakthrough in American manufacturing. Our proprietary biomanufacturing process represents a new, cost-effective, and advantaged way to produce platform chemicals domestically. With the foundation of existing infrastructure, we convert abundant, renewable American corn into high-value chemicals at scale. JOIN US AS WE ACCELERATE TO COMMERCIALIZATION

ROLE SUMMARY:

Bluestem Biosciences is seeking a motivated and detail-oriented Scientist to take charge of designing and analyzing enzyme engineering libraries that will enhance our core industrial chemical production. You'll design thoughtful experiments, manage their execution through our trusted network of contract research labs, and dive into the data to uncover meaningful insights. The perfect fit is someone with a background in protein engineering or computational biology who can work independently and with precision to create impactful experiments and interpret complex datasets. Working closely with Bluestem's R&D team, you'll play a key role in advancing the company's technology and innovation.

RESPONSIBILITIES:
  • Bring your enzyme library design toolkit to Bluestem to head up enzyme improvement approaches
  • Create clever screening or selection strategies to find the improvements within the enzyme diversity you've designed (e.g., activity, stability, selectivity)
  • Manage external experiments by working closely with our network of contract research organizations (CROs) to ensure successful execution and high-quality data delivery
  • Find the signal in the noise! Analyze and interpret large datasets from high-throughput enzyme screens and implement iterative improvements
  • Coordinate closely with the broader Bluestem R&D team on project outcomes, and share the commercial impact of your work with the whole company
  • Transfer optimized enzymes and protocols to the strain engineering team for integration into production hosts
  • Have an impact outside your domain expertise and contribute to the Bluestem R&D effort, taking an end-in-mind approach to building our success
REQUIREMENTS:
  • Ph.D. in Protein Engineering, Enzyme Engineering, Computational Biology, Biochemistry, Bioengineering, or a related scientific field, and 3+ years of hands-on industry experience
  • Demonstrated proficiency in modern protein and enzyme engineering techniques, including both computation approaches (e.g., AlphaFold, AI/ML-based design methods) and library design (e.g., directed evolution, rational design, saturation mutagenesis)
  • Experience managing workflows and projects with external partners or contract research organizations (CROs) is highly preferred
  • Familiarity with high-throughput screening (HTS) methods, enzyme activity assays, analytical methodologies, and selection-based screens
  • Exceptional attention to detail and the ability to successfully design complex experiments and analyze large-scale screening data
  • Strong organizational and time-management skills. Ability to work independently with minimal supervision while contributing to a collaborative team environment
  • Ability to effectively organize and analyze results and data (using Python, R, or JMP) and communicate results to the extended team

Bluestem is an equal opportunity workplace. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.