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Enzyme Engineering Jobs in Colorado (NOW HIRING)

Cascade Bio

Process Development Scientist

Denver, CO · On-site

$110K - $150K/yr

Interface with protein engineering efforts, translating process bottlenecks into enzyme engineering targets and back-integrating improved variants * Contribute broadly across the organization: at ...

Cascade Bio

Process Development Scientist

Denver, CO · On-site

$110K - $150K/yr

Interface with protein engineering efforts, translating process bottlenecks into enzyme engineering targets and back-integrating improved variants * Contribute broadly across the organization: at ...

Watchmaker Genomics

IT Systems Engineer

Boulder, CO · On-site

We believe that the intersection of biology, engineering, and computer science presents exciting ... enzymes that enable high-growth applications in genomics, molecular diagnostics, and personalized ...

Watchmaker Genomics

IT Systems Engineer

Boulder, CO · On-site

We believe that the intersection of biology, engineering, and computer science presents exciting ... enzymes that enable high-growth applications in genomics, molecular diagnostics, and personalized ...

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Enzyme Engineering information

See Colorado salary details

$27.8K

$77.7K

$162.4K

How much do enzyme engineering jobs pay per year?

As of Aug 20, 2026, the average yearly pay for enzyme engineering in Colorado is $77,689.00, according to ZipRecruiter salary data. Most workers in this role earn between $50,832.00 and $94,133.00 per year, depending on experience, location, and employer.

What is enzyme engineering?

An Enzyme Engineering job involves designing, modifying, and optimizing enzymes for industrial, medical, or research applications. Professionals in this field use biochemical, genetic, and computational techniques to enhance enzyme performance, stability, or specificity. They work in industries such as pharmaceuticals, biofuels, food processing, and environmental science to develop more efficient and sustainable biological solutions.

What does an enzyme engineer do?

In enzyme engineering, daily tasks often include designing and performing experiments to modify or improve enzyme function, analyzing data using biochemical and computational tools, and documenting research findings. Professionals regularly work with interdisciplinary teams, including chemists, biologists, and process engineers, to advance project goals and troubleshoot technical challenges. Managing laboratory equipment, ensuring compliance with safety protocols, and sometimes contributing to patent filings or journal publications are also common. This blend of hands-on lab work and collaborative problem-solving offers a dynamic and intellectually stimulating work environment.

What are the key skills and qualifications needed to thrive in enzyme engineering?

To excel in Enzyme Engineering, candidates typically need a strong background in biochemistry, molecular biology, and chemical engineering, often supported by an advanced degree. Familiarity with techniques such as protein expression, directed evolution, enzyme assays, and tools like PCR, chromatography systems, and computational modeling software is important, as are certifications in laboratory safety. Strong analytical thinking, problem-solving, and communication skills enable effective collaboration and innovation in research teams. These abilities are crucial for developing novel enzymes and optimizing biocatalysts for industrial, pharmaceutical, or environmental applications.

What are the applications of enzyme engineering?

Enzyme engineering involves modifying enzymes to improve their stability, activity, or specificity for various applications. It is widely used in industries such as pharmaceuticals for drug synthesis, in agriculture for pest control, and in environmental management for bioremediation. Enzyme engineers utilize techniques like directed evolution and computational design to develop enzymes suited for specific industrial processes.

What are the most commonly searched types of Enzyme Engineering jobs in Colorado?

The most popular types of Enzyme Engineering jobs in Colorado are:

What are popular job titles related to Enzyme Engineering jobs in Colorado?

For Enzyme Engineering jobs in Colorado, the most frequently searched job titles are:

What job categories do people searching Enzyme Engineering jobs in Colorado look for?

The top searched job categories for Enzyme Engineering jobs in Colorado are:

What cities in Colorado are hiring for Enzyme Engineering jobs?

Cities in Colorado with the most Enzyme Engineering job openings:

Enzyme Engineering jobs near you
Infographic showing various Enzyme Engineering job openings in Colorado as of August 2026, with employment types broken down into 90% Full Time, 6% Part Time, 1% Temporary, 2% Contract, and 1% Nights. Highlights an 85% Physical, 5% Hybrid, and 10% Remote job distribution, with an average salary of $77,689 per year, or $37.4 per hour.

Postdoctoral Researcher - Enzyme engineering for cell-free systems

National Renewable Energy Laboratory

Golden, CO • On-site

$76.60 - $126.40/hr

Other

Medical, Dental, Vision, Life, Retirement, PTO

Posted 2 days ago

New

Job description

Job Title

Postdoctoral Researcher – Enzyme Engineering for Cell‑Free Systems

Location

Golden, Colorado

Position Type

Postdoc (Fixed Term), 40 hours per week

Overview

RRES Center at NLR focuses on biological, chemical, and catalytic research in polymer design, upcycling, separations, synthetic biology, bioconversion, analytical sciences, computational modeling, and lignocellulosic chemistry. The successful candidate will work on the DOE‑funded project Integrating cell‑free systems and genome engineering to accelerate biosystems design for carbon‑negative biomanufacturing, developing optimized cell‑free systems for converting C1 substrates to sustainable biofuels and bioproducts.

Responsibilities
  • Identify, express, purify, and assay enzymes from full metabolic pathways.
  • Develop high‑throughput enzymatic assays to validate pathways.
  • Collaborate with data scientists to design efficient cell‑free production pathways.
  • Perform directed evolution, structure‑guided protein engineering, and machine‑learning‑guided protein engineering to improve enzyme and pathway function.
  • Conduct laboratory experiments safely and independently, with minimal supervision.
  • Plan and execute research in collaboration with multidisciplinary teams.
  • Communicate scientific results effectively in written and oral formats.
  • Author peer‑reviewed publications.
  • Work effectively in a large, multidisciplinary, multi‑institutional team of engineers and scientists.
Basic Qualifications
  • Recent PhD graduate within the last three years.
  • Experience with cloning, expression, and purification of proteins.
  • Experience with automation of biochemical assays.
  • Demonstrated experience in enzyme and/or protein engineering.
  • Ability to take initiative to set direction and goals for assigned tasks.
  • Strong troubleshooting and problem‑solving skills.
  • Strong record of quality peer‑reviewed publications.
  • Excellent safety record.
  • Ability to follow complex standard operating procedures with attention to detail.
Preferred Qualifications
  • Analytical chemistry experience with HPLC, GC‑FID, GC‑MS, and/or LC‑MS.
Annual Salary Range

$76,600 – $126,400

Benefits Summary
  • Medical, dental, and vision insurance.
  • Short‑term disability insurance.
  • Pension benefits.
  • 403(b) employee savings plan with employer match.
  • Life and accidental death and dismemberment insurance.
  • Personal time off and sick leave; paid holidays.
  • Possible performance‑, merit‑, and achievement‑based awards.
  • Possible relocation expense reimbursement.
Equal Opportunity Employer

All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity, genetic information, marital status, domestic partner status, military or veteran status, national origin, ancestry, race, religion, creed, sex, pregnancy, childbirth, breastfeeding, sexual orientation, or any other status protected by federal, state, or local law.

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