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Dynamic Light Scattering Jobs (NOW HIRING)

Scientist, Bioconjugation

Waltham, MA · On-site

$115K - $140K/yr

Experience with analytical characterization methods such as LC-MS, UPLC, capillary electrophoresis, SDS-PAGE, UV-Vis spectroscopy, and dynamic light scattering. * Knowledge of protein chemistry ...

Equipment Utilized If experimental, UV-Vis plate reader, dynamic light scattering (DLS), chromatography, and other basic equipment. Familiarity with SAXS/SANS is also ideal. Physical Demands and Work ...

Experience with biophysical characterization of protein complexes, including techniques like dynamic light scattering (DLS) and analytical ultracentrifugation (AUC). * Experience with expression and ...

Engineer precise fluid dynamics (shear-thinning behavior, yield stress) tailored for advanced ... Adjust photoinitiator packages and resin refractive indices to overcome light scattering caused by ...

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Dynamic Light Scattering information

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How much do dynamic light scattering jobs pay per hour?

As of Sep 6, 2026, the average hourly pay for dynamic light scattering in the United States is $71.40, according to ZipRecruiter salary data. Most workers in this role earn between $58.17 and $83.41 per hour, depending on experience, location, and employer.

What is dynamic light scattering?

Dynamic Light Scattering (DLS) is an analytical technique used to determine the size distribution of small particles or molecules in suspension or solution. By measuring the fluctuations in light intensity scattered by particles as they undergo Brownian motion, DLS can provide valuable information about particle size, distribution, and aggregation state. This technique is commonly used in fields such as chemistry, biology, and materials science to characterize nanoparticles, proteins, polymers, and other colloidal systems.

What skills and qualifications are needed to work with dynamic light scattering?

To thrive as a Dynamic Light Scattering (DLS) Scientist, you need a strong background in physical chemistry, materials science, or a related field, often with a relevant advanced degree. Expertise with DLS instrumentation, data analysis software, and knowledge of nanoparticle characterization techniques are typically required. Attention to detail, problem-solving skills, and the ability to communicate complex findings clearly set top candidates apart. These abilities ensure accurate data interpretation, effective collaboration, and reliable results in research and industrial applications.

What are common challenges faced when working with dynamic light scattering techniques?

Professionals using Dynamic Light Scattering often encounter challenges such as sample contamination, aggregation, or improper sample preparation, which can affect data accuracy. Additionally, interpreting DLS data requires a solid understanding of both the instrument and the principles behind particle size analysis, as artifacts and multiple scattering can complicate results. Collaboration with other scientists, such as chemists or biophysicists, is common to troubleshoot issues and optimize protocols, making teamwork and communication important skills in this role.

What is the difference between Dynamic Light Scattering vs Particle Characterization Specialist?

AspectDynamic Light ScatteringParticle Characterization Specialist
CredentialsPhysics, Chemistry, or Materials Science degrees; training in DLS techniquesSimilar degrees; expertise in various particle analysis methods including DLS
Work EnvironmentLaboratories, research facilities, pharmaceutical or biotech companiesLaboratories, R&D departments, quality control labs in similar industries
Industry UsageUsed for measuring nanoparticle size, aggregation, and stabilityUses DLS along with other techniques for comprehensive particle analysis

While Dynamic Light Scattering focuses specifically on measuring particle size distribution using light scattering, a Particle Characterization Specialist often employs multiple techniques, including DLS, to analyze particles comprehensively. Both roles are vital in research and quality control within similar industries, with overlapping skills and work environments.

More about Dynamic Light Scattering jobs

What cities are hiring for Dynamic Light Scattering jobs?

Cities with the most Dynamic Light Scattering job openings:

What states have the most Dynamic Light Scattering jobs?

States with the most job openings for Dynamic Light Scattering jobs include:

Infographic showing various Dynamic Light Scattering job openings in the United States as of August 2026, with employment types broken down into 100% Contract. Highlights an 100% In-person job distribution, with an average salary of $148,520 per year, or $71.4 per hour.

Scientist, Bioconjugation

Dyne Therapeutics

Waltham, MA • On-site

$115K - $140K/yr

Full-time

Posted 10 days ago


Key responsibilities

  • Designs and conducts experiments to synthesize and optimize the conjugation of oligonucleotides to proteins, peptides, and antibodies.

  • Develops and evaluates novel conjugation strategies, linker technologies, and site-specific modification approaches.

  • Purifies and characterizes bioconjugates using chromatographic, spectroscopic, and complementary analytical techniques.


Job description

Company Overview:
Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as preclinical programs for facioscapulohumeral muscular dystrophy (FSHD), Pompe disease and multiple DMD mutations. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.
Role Summary:
The Scientist, Bioconjugation designs, synthesizes, purifies, characterizes, and optimizes novel bioconjugates that support Dyne's therapeutic pipeline. This role applies expertise in bioconjugation chemistry, protein purification, oligonucleotide conjugation, and analytical characterization to solve scientific and technical challenges. Prior experience in design, synthesis, purification, and/or characterization of antibody-drug conjugates (ADCs) and/or antibody-oligonucleotide conjugates (AOCs) is a plus. The Scientist collaborates closely with colleagues across chemistry, protein engineering, analytical sciences, process development, biology, and other functions to advance therapeutic programs from discovery through development.
This position is based in Waltham, MA
Primary Responsibilities Include:
  • Designs and conducts experiments to synthesize and optimize the conjugation of oligonucleotides to proteins, peptides, and antibodies.
  • Develops and evaluates novel conjugation strategies, linker technologies, and site-specific modification approaches.
  • Purifies and characterizes bioconjugates using chromatographic, spectroscopic, and complementary analytical techniques.
  • Analyzes and interprets experimental data to guide molecular design, experimental strategy, and process optimization.
  • Independently troubleshoots complex synthetic, purification, and analytical challenges.
  • Collaborates with cross-functional teams to advance therapeutic candidates and achieve project milestones.
  • Maintains detailed and accurate experimental records and communicates findings through technical reports, presentations, and team discussions.
  • Contributes to internal technology development initiatives and bioconjugation platform innovation.
  • Supports the transfer of conjugation processes to development and manufacturing teams as programs advance.
  • Maintains current knowledge of emerging technologies and scientific literature in bioconjugation, protein chemistry, and oligonucleotide therapeutics.

Education and Skills Requirements:
  • PhD in chemistry, biochemistry, chemical biology, pharmaceutical sciences, or a related scientific discipline with 0-3 years of industry experience; or a master's degree with 8+ years of relevant industry experience.
  • Hands-on experience in bioconjugation chemistry and protein purification.
  • Experience with the conjugation of proteins, peptides, antibodies, or oligonucleotides.
  • Strong understanding of linker chemistry, conjugation mechanisms, and site-specific modification strategies.
  • Hands-on experience with purification techniques, including HPLC, FPLC, size-exclusion chromatography, ion-exchange chromatography, and affinity chromatography.
  • Experience with analytical characterization methods such as LC-MS, UPLC, capillary electrophoresis, SDS-PAGE, UV-Vis spectroscopy, and dynamic light scattering.
  • Knowledge of protein chemistry, oligonucleotide therapeutics, or antibody-based therapeutics.
  • Ability to independently design and execute experimental work within defined research projects, applying sound scientific methodology to address increasingly complex problems.
  • Ability to analyze, interpret, and clearly communicate experimental data to support program advancement and scientific decision-making.
  • Strong scientific curiosity and an innovative, solution-oriented mindset.
  • Excellent experimental planning, execution, documentation, and organizational skills.
  • Effective written and verbal communication skills.
  • Strong cross-functional collaboration skills and the ability to work effectively with internal partners toward shared scientific objectives.
  • Ability to manage multiple priorities, meet timelines, and thrive in a fast-paced, collaborative biotechnology environment.

#LI-Onsite
MA Pay Range
$115,000-$140,000 USD
The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills.
The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.
Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.