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Dynamic Light Scattering Jobs in California (NOW HIRING)

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Scientist I

San Diego, CA · On-site

$48/hr

Proficiency with standard LNP characterization methods, including Dynamic Light Scattering (DLS), Zeta potential, and Ribogreen assays. * Preferred Skills: Prior experience with Tangential Flow ...

APN Software Services Inc

Scientist I

San Diego, CA · On-site

Proficiency with standard LNP characterization methods, including Dynamic Light Scattering (DLS), Zeta potential, and Ribogreen assays. * Preferred Skills: Prior experience with Tangential Flow ...

Dexcom, Inc.

Production Chemist 3

San Diego, CA · On-site

... Dynamic Light Scattering, and UV-Vis spectroscopy. * You will perform data analysis on results and statistical analysis on data and secondary data review when required. * You will ensure samples are ...

Dexcom

Production Chemist 3

San Diego, CA

... Dynamic Light Scattering, and UV-Vis spectroscopy. * You will perform data analysis on results and statistical analysis on data and secondary data review when required. * You will ensure samples are ...

Aeva, Inc.

Optical Engineer

Mountain View, CA

$132K - $179K/yr

Experience in tolerance analysis, stray-light and scattering analysis * Experience with precision ... Be part of a fast paced and dynamic team * Very competitive compensation and meaningful stock ...

Aeva, Inc.

Optical Engineer

Mountain View, CA

$132K - $179K/yr

Experience in tolerance analysis, stray-light and scattering analysis * Experience with precision ... Be part of a fast paced and dynamic team * Very competitive compensation and meaningful stock ...

Aeva, Inc.

Optical Engineer

Mountain View, CA · On-site

$132K - $179K/yr

Experience in tolerance analysis, stray-light and scattering analysis * Experience with precision ... Be part of a fast paced and dynamic team * Very competitive compensation and meaningful stock ...

Arcadia Science

Imaging Specialist

Emeryville, CA · On-site

... dynamics (~500 fps full chip, faster in ROI), and a Leica Stellaris 8 for coherent Raman scattering ... Demonstrated ability to maintain and troubleshoot complex optical systems, including light paths ...

Arcadia Science

Imaging Specialist

Emeryville, CA · On-site

... dynamics (~500 fps full chip, faster in ROI), and a Leica Stellaris 8 for coherent Raman scattering ... Demonstrated ability to maintain and troubleshoot complex optical systems, including light paths ...

All JobsDynamic Light Scattering JobsDynamic Light Scattering Jobs in California

Dynamic Light Scattering information

What is another name for dynamic light scattering?

Dynamic light scattering (DLS) is also known as photon correlation spectroscopy or quasi-elastic light scattering. These terms refer to the technique used to measure particle size distribution in colloidal suspensions and solutions. Understanding these names can help in research and technical documentation related to the method.

How accurate is dynamic light scattering?

Dynamic Light Scattering (DLS) is a widely used technique for measuring particle size distribution in colloidal suspensions, with typical accuracy within 5-10% for monodisperse samples. Factors such as sample quality, instrument calibration, and data analysis methods influence its precision, making it suitable for qualitative and semi-quantitative assessments rather than highly precise measurements. Proper training and calibration are essential for obtaining reliable results in a laboratory setting.

What are the key skills and qualifications needed to thrive as a Dynamic Light Scattering (DLS) Scientist, and why are they important?

To thrive as a Dynamic Light Scattering (DLS) Scientist, you need a strong background in physical chemistry, materials science, or a related field, often with a relevant advanced degree. Expertise with DLS instrumentation, data analysis software, and knowledge of nanoparticle characterization techniques are typically required. Attention to detail, problem-solving skills, and the ability to communicate complex findings clearly set top candidates apart. These abilities ensure accurate data interpretation, effective collaboration, and reliable results in research and industrial applications.

What is Dynamic Light Scattering?

Dynamic Light Scattering (DLS) is an analytical technique used to determine the size distribution of small particles or molecules in suspension or solution. By measuring the fluctuations in light intensity scattered by particles as they undergo Brownian motion, DLS can provide valuable information about particle size, distribution, and aggregation state. This technique is commonly used in fields such as chemistry, biology, and materials science to characterize nanoparticles, proteins, polymers, and other colloidal systems.

What are some common challenges faced by professionals working with Dynamic Light Scattering (DLS) techniques in a laboratory setting?

Professionals using Dynamic Light Scattering often encounter challenges such as sample contamination, aggregation, or improper sample preparation, which can affect data accuracy. Additionally, interpreting DLS data requires a solid understanding of both the instrument and the principles behind particle size analysis, as artifacts and multiple scattering can complicate results. Collaboration with other scientists, such as chemists or biophysicists, is common to troubleshoot issues and optimize protocols, making teamwork and communication important skills in this role.

What science careers are in demand?

Careers related to Dynamic Light Scattering include roles such as research scientists, laboratory technicians, and materials scientists, especially in fields like nanotechnology, biophysics, and materials science. These positions often require knowledge of optics, spectroscopy, and data analysis, with demand driven by advancements in nanomaterials, pharmaceuticals, and biomedical research.

What is the difference between Dynamic Light Scattering vs Particle Characterization Specialist?

AspectDynamic Light ScatteringParticle Characterization Specialist
CredentialsPhysics, Chemistry, or Materials Science degrees; training in DLS techniquesSimilar degrees; expertise in various particle analysis methods including DLS
Work EnvironmentLaboratories, research facilities, pharmaceutical or biotech companiesLaboratories, R&D departments, quality control labs in similar industries
Industry UsageUsed for measuring nanoparticle size, aggregation, and stabilityUses DLS along with other techniques for comprehensive particle analysis

While Dynamic Light Scattering focuses specifically on measuring particle size distribution using light scattering, a Particle Characterization Specialist often employs multiple techniques, including DLS, to analyze particles comprehensively. Both roles are vital in research and quality control within similar industries, with overlapping skills and work environments.

What is the dynamic light scattering method?

Dynamic Light Scattering (DLS) is a technique used to measure the size distribution of small particles or molecules in suspension by analyzing fluctuations in scattered light caused by their Brownian motion. It is commonly employed in research and quality control environments, requiring specialized instruments and data analysis skills. DLS helps determine particle size, stability, and aggregation in various scientific and industrial applications.
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Infographic showing various Dynamic Light Scattering job openings in California as of June 2026, with employment types broken down into 100% Full Time. Highlights an 89% In-person, and 11% Remote job distribution.

Principal Scientist - Analytical Methods Development

Programmable Medicine Operatin

Redwood City, CA • On-site

$165K - $200K/yr

Full-time

Medical, Dental, Vision

Posted 18 hours ago

Job description

Programmable Medicine, a clinical stage biopharmaceutical company located in Redwood City, is seeking a motivated Chemist/Sr. Chemist Analytical Method Development. We are focused on developing novel nanomedicines, HD therapeutics (HDTs), to treat unmet medical needs in ophthalmology, neurology, inflammatory diseases, and neuro-oncology. Our HD platform builds therapeutics that are selectively taken up only by inflamed tissues, allowing us to treat diseases with unprecedented precision.
The successful candidate will provide scientific leadership for the development, qualification, stage-appropriate validation of analytical methods supporting complex large molecule therapeutics, including antibody drug conjugates, polymer-based platforms, and other nanomedicine products. The successful candidate will partner closely with Chemistry, Translational, Process Development, Formulation Development, Quality, Regulatory Affairs, Manufacturing, and external contract laboratories to establish robust analytical strategies that support product characterization, process understanding, product test and release, and regulatory submissions.
  • Subject matter expert in analytical methods development that uses scientific knowledge and experience to independently design, plan and execute studies in support of preclinical through Phase 2 programs
  • Performs analytical development and optimizes methods in support of preclinical studies through Phase 2
  • Creates and implements novel ideas and techniques to support analytical activities
  • Leads analytical technology transfersto GLP laboratories in support of GMP production
  • Writes analytical method development reports, SOPs, and analytical sections of regulatory submissions
  • Supervises laboratory personnel including setting priorities, monitoring work, execution totimelines, training to appropriate SOPs, meeting quality standards, and timely completion of documentation

Job Requirements
  • PhD in Analytical Chemistry or related discipline and 10+ years of relevant experience with at least 6 years of experience in the biotechnology/pharmaceutical or related industry
  • Demonstrated experience supporting complex large molecule therapeutics, including at least one of the following: antibody drug conjugates, dendrimers, polymers, biologics, bioconjugates, nanoparticles, or related products.
  • Extensive experience developing analytical methods supporting products from discovery through clinical development
  • Thorough understanding of analytical chemistry and a well-developed understanding of potential in-process impurities generated in production of antibody drug conjugates or polymer-drug conjugates
  • Strong working knowledge of analytical techniques, including: HPLC, SEC, LC-MS/MS, LC-MS, NMR spectroscopy, UV-Vis spectroscopy, , Dynamic Light Scattering (DLS), Zeta potential analysis, Multi-angle light scattering (MALS),.
  • Experience leading analytical method transfers to GMP manufacturing sites and familiarity with CDMO and CRO management
  • Strong knowledge of FDA, ICH, USP, EMA, and global CMC regulatory requirements and experience supporting regulatory submissions, including IND, NDA, and associated agency responses
  • Demonstrated understanding of cross-functional team membership related to drug development
  • Excellent project management skills with proven ability to meet multiple deadlines across a variety of projects/programs, with a high degree of accuracy and efficiency
  • Previous experience supervising and optimizing the performance of a small scientific team
  • Extensive experience in developing analytical methods using fundamental scientific principles including peer reviewed publications as co-author or lead author

About Programmable Medicine
This is a unique opportunity to join a team focused on the development of a new class of precision medicines that selectively treat diseased cells in regions of inflammation. By making precision medicine even more precise, our nanomedicine technology has the potential to change the standard of care across ophthalmology, neurology, inflammatory diseases and neuro-oncology. You will have the opportunity to learn new skills and gain a better understanding of cutting-edge technology.
We have a comprehensive compensation package including fully paid medical, dental and vision benefits for you and your family. We want our employees to become shareholders and offer new hire stock options. The company also offers participation in the annual bonus program. The salary range for MS candidates located in the Bay Area, with a minimum of 8 years of industry experience is $165,000 - $200,000, depending on years of experience and relevant skill sets.

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