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Dynamic Light Scattering Jobs in California (NOW HIRING)

IT Engagements

Scientist I

San Diego, CA · On-site

$48/hr

Proficiency with standard LNP characterization methods, including Dynamic Light Scattering (DLS), Zeta potential, and Ribogreen assays. * Preferred Skills: Prior experience with Tangential Flow ...

APN Software Services Inc

Scientist I

San Diego, CA · On-site

Proficiency with standard LNP characterization methods, including Dynamic Light Scattering (DLS), Zeta potential, and Ribogreen assays. * Preferred Skills: Prior experience with Tangential Flow ...

Waters Corporation

Development Engineer I

Goleta, CA · On-site

Join a dynamic R&D team focused on developing the next generation of analytical instruments for the ... Exposure to light scattering instrumentation or related analytical techniques. * Experience ...

Genentech

Scientist 3

San Diego, CA · On-site

$89K - $166K/yr

You have are highly proficient with standard LNP characterization methods, including Dynamic Light Scattering (DLS), Zeta potential, and Ribogreen assays. * You have a demonstrated level of expertise ...

Amgen

Scientist - Protein Biochemist

Thousand Oaks, CA

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Experience with biophysical characterization of protein complexes, including techniques like dynamic light scattering (DLS) and analytical ultracentrifugation (AUC). * Experience with expression and ...

Waters Corporation

Sr. Mechanical Engineer

Goleta, CA · On-site

$112K - $148K/yr

Overview Join a dynamic and innovative R&D team dedicated to developing the next generation of light scattering, field-flow fractionation (FFF), and chromatography-based analytical instruments. As a ...

Amgen, Inc.

Scientist - Protein Biochemist

Thousand Oaks, CA · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Experience with biophysical characterization of protein complexes, including techniques like dynamic light scattering (DLS) and analytical ultracentrifugation (AUC). * Experience with expression and ...

Waters Corporation

Sr. Mechanical Engineer

Goleta, CA · On-site

$112K - $148K/yr

Overview Join a dynamic and innovative R&D team dedicated to developing the next generation of light scattering, field-flow fractionation (FFF), and chromatography-based analytical instruments. As a ...

Waters Corporation

Sr. Mechanical Engineer

Goleta, CA

$112K - $148K/yr

Overview Join a dynamic and innovative R&D team dedicated to developing the next generation of light scattering, field-flow fractionation (FFF), and chromatography-based analytical instruments. As a ...

Waters Corporation

Sr. Mechanical Engineer

Goleta, CA · On-site

$112K - $148K/yr

Join a dynamic and innovative R&D team dedicated to developing the next generation of light scattering, field-flow fractionation (FFF), and chromatography-based analytical instruments. As a Senior ...

Amgen, Inc.

Associate Scientist

Thousand Oaks, CA · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Preferred experience in biophysical analysis (Light scattering, DSF, AUC, FFF), mass spectrometry ... Ability to learn and act on dynamic information at a rapid pace, hard-working and collaborative ...

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All JobsDynamic Light Scattering JobsDynamic Light Scattering Jobs in California

Dynamic Light Scattering information

What is dynamic light scattering?

Dynamic Light Scattering (DLS) is an analytical technique used to determine the size distribution of small particles or molecules in suspension or solution. By measuring the fluctuations in light intensity scattered by particles as they undergo Brownian motion, DLS can provide valuable information about particle size, distribution, and aggregation state. This technique is commonly used in fields such as chemistry, biology, and materials science to characterize nanoparticles, proteins, polymers, and other colloidal systems.

What skills and qualifications are needed to work with dynamic light scattering?

To thrive as a Dynamic Light Scattering (DLS) Scientist, you need a strong background in physical chemistry, materials science, or a related field, often with a relevant advanced degree. Expertise with DLS instrumentation, data analysis software, and knowledge of nanoparticle characterization techniques are typically required. Attention to detail, problem-solving skills, and the ability to communicate complex findings clearly set top candidates apart. These abilities ensure accurate data interpretation, effective collaboration, and reliable results in research and industrial applications.

What are common challenges faced when working with dynamic light scattering techniques?

Professionals using Dynamic Light Scattering often encounter challenges such as sample contamination, aggregation, or improper sample preparation, which can affect data accuracy. Additionally, interpreting DLS data requires a solid understanding of both the instrument and the principles behind particle size analysis, as artifacts and multiple scattering can complicate results. Collaboration with other scientists, such as chemists or biophysicists, is common to troubleshoot issues and optimize protocols, making teamwork and communication important skills in this role.

What is the difference between Dynamic Light Scattering vs Particle Characterization Specialist?

AspectDynamic Light ScatteringParticle Characterization Specialist
CredentialsPhysics, Chemistry, or Materials Science degrees; training in DLS techniquesSimilar degrees; expertise in various particle analysis methods including DLS
Work EnvironmentLaboratories, research facilities, pharmaceutical or biotech companiesLaboratories, R&D departments, quality control labs in similar industries
Industry UsageUsed for measuring nanoparticle size, aggregation, and stabilityUses DLS along with other techniques for comprehensive particle analysis

While Dynamic Light Scattering focuses specifically on measuring particle size distribution using light scattering, a Particle Characterization Specialist often employs multiple techniques, including DLS, to analyze particles comprehensively. Both roles are vital in research and quality control within similar industries, with overlapping skills and work environments.

What are popular job titles related to Dynamic Light Scattering jobs in California?

For Dynamic Light Scattering jobs in California, the most frequently searched job titles are:

What job categories do people searching Dynamic Light Scattering jobs in California look for?

The top searched job categories for Dynamic Light Scattering jobs in California are:

What cities in California are hiring for Dynamic Light Scattering jobs?

Cities in California with the most Dynamic Light Scattering job openings:

Dynamic Light Scattering jobs near you
Infographic showing various Dynamic Light Scattering job openings in California as of June 2026, with employment types broken down into 100% Full Time. Highlights an 89% In-person, and 11% Remote job distribution.

Principal Scientist - Analytical Methods Development

Programmable Medicine Operatin

Redwood City, CA • On-site

$165K - $200K/yr

Full-time

Medical, Dental, Vision

Posted 22 days ago

Job description

Who We Are
Programmable Medicine is a pre-revenue, clinical-stage biotechnology company focused on discovering and developing innovative therapies for patients with serious diseases. The company operates across multiple legal entities and partners with external CROs, CMOs, and research institutions globally. Backed by leading venture capital investors, Programmable Medicine is building a scalable technical operations function to support rapid growth and pipeline advancement.
The Position
The successful candidate will provide scientific leadership for the development, qualification, stage-appropriate validation of analytical methods supporting complex large molecule therapeutics, including antibody drug conjugates, polymer-based platforms, and other nanomedicine products. The successful candidate will partner closely with Chemistry, Translational, Process Development, Formulation Development, Quality, Regulatory Affairs, Manufacturing, and external contract laboratories to establish robust analytical strategies that support product characterization, process understanding, product test and release, and regulatory submissions.
  • Subject matter expert in analytical methods development that uses scientific knowledge and experience to independently design, plan and execute studies in support of preclinical through Phase 2 programs
  • Performs analytical development and optimizes methods in support of preclinical studies through Phase 2
  • Creates and implements novel ideas and techniques to support analytical activities
  • Leads analytical technology transfersto GLP laboratories in support of GMP production
  • Writes analytical method development reports, SOPs, and analytical sections of regulatory submissions
  • Supervises laboratory personnel including setting priorities, monitoring work, execution of timelines, training to appropriate SOPs, meeting quality standards, and timely completion of documentation

Job Requirements
  • PhD in Analytical Chemistry or related discipline and 10+ years of relevant experience with at least 6 years of experience in the biotechnology/pharmaceutical or related industry
  • Demonstrated experience supporting complex large molecule therapeutics, including at least one of the following: antibody drug conjugates, dendrimers, polymers, biologics, bioconjugates, nanoparticles, or related products.
  • Extensive experience developing analytical methods supporting products from discovery through clinical development
  • Thorough understanding of analytical chemistry and a well-developed understanding of potential in-process impurities generated in production of antibody drug conjugates or polymer-drug conjugates
  • Strong working knowledge of analytical techniques, including: HPLC, SEC, LC-MS/MS, LC-MS, NMR spectroscopy, UV-Vis spectroscopy, , Dynamic Light Scattering (DLS), Zeta potential analysis, Multi-angle light scattering (MALS),.
  • Experience leading analytical method transfers to GMP manufacturing sites and familiarity with CDMO and CRO management
  • Strong knowledge of FDA, ICH, USP, EMA, and global CMC regulatory requirements and experience supporting regulatory submissions, including IND, NDA, and associated agency responses
  • Demonstrated understanding of cross-functional team membership related to drug development
  • Excellent project management skills with proven ability to meet multiple deadlines across a variety of projects/programs, with a high degree of accuracy and efficiency
  • Previous experience supervising and optimizing the performance of a small scientific team
  • Extensive experience in developing analytical methods using fundamental scientific principles including peer reviewed publications as co-author or lead author

About Programmable Medicine
This is a unique opportunity to join a team focused on the development of a new class of precision medicines that selectively treat diseased cells in regions of inflammation. By making precision medicine even more precise, our nanomedicine technology has the potential to change the standard of care across ophthalmology, neurology, inflammatory diseases and neuro-oncology. You will have the opportunity to learn new skills and gain a better understanding of cutting-edge technology.
We have a comprehensive compensation package including fully paid medical, dental and vision benefits for you and your family. We want our employees to become shareholders and offer new hire stock options. The company also offers participation in the annual bonus program. The salary range for MS candidates located in the Bay Area, with a minimum of 8 years of industry experience is $165,000 - $200,000, depending on years of experience and relevant skill sets.

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