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Downstream Processing Jobs in Maryland (NOW HIRING)

Umd

Assistant Research Professor

College Park, MD

$110K - $130K/yr

In the biomanufacturing testbeds, the NISTCHO and its product, the cNISTmAb, are being used to develop and evaluate upstream and downstream processes and study the effect of process modifications on ...

Ignite IT

Data Engineering Lead

Suitland, MD

Manual gating and handoff processes * Analyze legacy storage models and design target-state data ... Downstream compatibility across subsystems * Develop dashboards and reporting mechanisms providing:

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Downstream Processing information

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$13

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$34

How much do downstream processing jobs pay per hour?

As of Aug 9, 2026, the average hourly pay for downstream processing in Maryland is $23.95, according to ZipRecruiter salary data. Most workers in this role earn between $19.13 and $27.31 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in downstream processing, and why are they important?

To thrive in Downstream Processing, you typically need a background in biochemistry, chemical engineering, or a related field, along with experience in purification and separation techniques. Familiarity with technical tools such as chromatography systems, filtration units, and process control software, as well as cGMP certification, is often required. Strong attention to detail, problem-solving skills, and effective teamwork are valuable soft skills for this role. These competencies ensure efficient production, product quality, and compliance in highly regulated biopharmaceutical environments.

How does downstream processing work?

Downstream processing in a biological or pharmaceutical context involves the purification and recovery of target products, such as proteins or vaccines, from a complex mixture. It typically includes steps like filtration, chromatography, and concentration, often requiring specialized equipment and quality control measures. Downstream processing technicians need knowledge of bioprocessing techniques and safety protocols to ensure product purity and compliance with regulations.

What are the typical daily responsibilities of someone working in downstream processing?

In Downstream Processing, your daily activities often include operating and optimizing purification systems, conducting in-process testing, and meticulously documenting process parameters and results. You’ll collaborate closely with upstream teams, quality control labs, and engineering staff to troubleshoot and improve workflows. Managing equipment maintenance, adhering to safety and compliance standards, and actively participating in process development projects are also key facets of the job. This hands-on role is essential for ensuring the purity and consistency of biopharmaceutical products.

What is downstream processing?

A Downstream Processing (DSP) job involves purifying and recovering biomolecules, such as proteins or vaccines, after fermentation or cell culture. Professionals in this role use techniques like filtration, chromatography, and centrifugation to ensure product purity and quality. They work in industries like pharmaceuticals, biotechnology, and bioprocessing. Key responsibilities include optimizing purification processes, troubleshooting equipment, and ensuring compliance with regulatory standards.

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What cities in Maryland are hiring for Downstream Processing jobs? Cities in Maryland with the most Downstream Processing job openings:
Downstream Processing jobs near you
Infographic showing various Downstream Processing job openings in Maryland as of August 2026, with employment types broken down into 80% Full Time, 15% Part Time, 1% Temporary, 3% Contract, and 1% Nights. Highlights an 92% Physical, 3% Hybrid, and 5% Remote job distribution, with an average salary of $49,807 per year, or $23.9 per hour.

Assistant Research Professor

Umd

College Park, MD

$110K - $130K/yr

Full-time

Re-posted 27 days ago

Job description

Job Description SummaryOrganization's Summary Statement:
IBBR is a joint research enterprise of the University of Maryland, College Park, the University of Maryland, Baltimore, and the National Institute of Standards and Technology. IBBR leverages state-of-art integrative methods for bioanalytical, biophysical and structural characterization of biomolecules: cryo-electron microscopy, nuclear magnetic resonance, x-ray crystallography, small angle neutron and x-ray scattering and mass spectrometry. IBBR researchers seek to advance therapeutic development, biomanufacturing, and state-of-the-art measurement technologies, to support accelerated delivery of safe and effective medicines to the public. IBBR is a major initiative and supported in part by the University of Maryland Strategic Partnership: MPowering the State (MPower), an initiative designed to achieve innovation and impact through collaboration.
Job Description Summary:
The Institute for Bioscience and Biotechnology Research (IBBR) is seeking an Assistant Research Professor in the area of process characterization, modeling (digital twin) and control for biomanufacturing, with a focus on applications to mammalian cell bioprocesses. The successful candidate will coordinate interactions with internal and external collaborators and facility users. They are expected to be involved directly in research, both through leading their own novel research and through consultation, assistance and/or collaboration on projects with facility users. As needed, they will support and train internal students and postdocs, as well as external users from other institutions. The biomanufacturing testbed facility is underpinned by a newly developed NIST reference material (RM), so called NISTCHO. NISTCHO is a CHO cell line expressing the amino acid sequences of the NISTmAb. In the biomanufacturing testbeds, the NISTCHO and its product, the cNISTmAb, are being used to develop and evaluate upstream and downstream processes and study the effect of process modifications on product CQAs. The testbeds are also being used to explore new process monitoring technologies for upstream analysis such as new probes, developed for in-line and at-line monitoring.
Minimum Qualifications:
Education: Ph.D. in in bioengineering, biochemical engineering, chemistry, biochemistry, biophysics, or related fields.
Experience: At least 3 years of prior experience working with bioprocess characterization, monitoring and modeling; experience in managing research projects, drafting reports and proposal, representing research programs to external stakeholders and providing training in research techniques.
Physical Demands: NA
Preferences: NA
Licenses/ Certifications: NAAdditional Job Details

Required Application Materials:

1. Personal Research Statement

2. Curriculum Vitae

3. List of References (no emails sent from the system)

Best Consideration Date:

01/31/2026

Posting Close Date: NA

Open Until Filled:

Yes

Financial Disclosure RequiredNo

For more information on Financial Disclosure, please visit Maryland's State Ethics Commission website.

DepartmentCMNS-IBBRWorker Sub-Type Faculty RegularSalary Range$110,000- $130,000
Benefits Summary

For more information on Regular Faculty benefits, select this link.

Background Checks

Offers of employment are contingent on completion of a background check. Information reported by the background check will not automatically disqualify anyone from employment. Before any adverse decision, the finalist will have an opportunity to provide information to the University regardingdisclosablebackground checkinformation. The University reserves the right to rescind the offer of employment or otherwise decline or terminate employment if the information reported by the background check is deemed incompatible with the position, regardless of when the background check is completed.

Employment Eligibility

The successful candidate must complete employment eligibility verification (on Form I-9) by presenting documents that establish identity and work authorization within the timeframe required by federal immigration law, and where applicable, to demonstrate renewed employment authorization. Failure to complete employment eligibility verification or reverification within the timeframe set forth by law may result in suspension or termination of employment.

EEO Statement

The University of Maryland, College Park is an Equal Opportunity Employer. All qualified applicants will receive equal consideration for employment. Please read the University's Equal Employment Opportunity Statement of Policy.

Title IX Non-Discrimination NoticeResources

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