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Director Variant Analyst Jobs (NOW HIRING)

Natera

Associate Laboratory Director

San Carlos, CA · On-site

$128K - $167K/yr

As the Associate/Laboratory Director, you have clinical oversight of Natera's laboratory testing ... analysis, NGS, and other methodologies. * Oversee the review of genetic and CNV variant data ...

Angenex

Remote Junior Data Analyst

Paterson, NJ · Remote

Qualifications: 2+ years of direct and hands-on experience providing solutions. Bachelor's degree ... Solid communication and presentation skills Prior experience with any variant of SQL preferred.

Natera

Associate/Laboratory Director

San Carlos, CA

$128K - $167K/yr

Oversee the review of genetic and CNV variant data: interpret NGS results in the context of medical ... Analyze lab data, contribute to or write publications for high-quality scientific journals. * May ...

Natera

Assistant Laboratory Director

Austin, TX · On-site

... analysis, NGS, and other methodologies. * Oversee the review of genetic and CNV variant data ... Current California laboratory director license as a Clinical Genetic Molecular Biologist or ...

Natera

Assistant Laboratory Director

Austin, TX

... analysis, NGS, and other methodologies. * Oversee the review of genetic and CNV variant data ... Current California laboratory director license as a Clinical Genetic Molecular Biologist or ...

Natera

Associate/Laboratory Director

San Carlos, CA · On-site

$128K - $167K/yr

Oversee the review of genetic and CNV variant data: interpret NGS results in the context of medical ... Analyze lab data, contribute to or write publications for high-quality scientific journals. * May ...

Natera

Laboratory Director

San Carlos, CA · On-site

$225K - $280K/yr

Ensure acceptable levels of analytical performance for CGP assays, compliance with applicable ... Strong familiarity with professional guidelines for somatic variant interpretation (e.g., AMP/ASCO ...

Baylor Genetics

Clinical Genomic Scientist - WGS

Our scientists assist laboratory directors and R&D with validation of cutting-edge technologies and ... Desired: experience in bioinformatics analysis, variant effect prediction algorithms, and scripting ...

Veracyte

Sr. Director, Lab Pipelines and LIMS

San Diego, CA · On-site

$112K - $147K/yr

Direct experience with LIMS platforms and secondary analysis pipelines (e.g., sequence data processing, variant calling, annotation workflows, or similar data-intensive pipelines) * Strong ...

Fremont Solutions Group

SAP Business Analyst

Farmington, CT · On-site

$56.50 - $75.50/hr

Complete other tasks assigned from the direct supervisor per business requirement. * Weekends ... SAP SD, CS, MM, Variant Configuration. * ITIL and project and process management skills. * Ability ...

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Director Variant Analyst information

What is a director variant analyst?

A Director Variant Analyst is a senior professional responsible for overseeing the analysis and interpretation of genetic variants within an organization, typically in a clinical or research genetics setting. They lead teams that evaluate genetic data to determine the clinical significance of DNA sequence variations, which is crucial for diagnosing genetic disorders or informing personalized medicine. The director collaborates with scientists, clinicians, and laboratory staff to ensure the accuracy and quality of genetic variant analysis and reporting. They may also contribute to the development of protocols, implementation of new technologies, and compliance with industry regulations. This role requires deep expertise in genetics, bioinformatics, and leadership.

What are the key skills and qualifications needed to thrive as a director variant analyst, and why are they important?

To thrive as a Director Variant Analyst, you need advanced expertise in genomics, variant interpretation, and bioinformatics, often supported by a PhD or equivalent experience in genetics or molecular biology. Familiarity with next-generation sequencing (NGS) platforms, variant annotation tools, and clinical databases, along with relevant certifications such as board certification in clinical molecular genetics, is highly valued. Strong leadership, decision-making, and communication skills are critical for managing teams and collaborating across departments. These competencies ensure accurate and efficient analysis of genetic data, drive innovation, and support high-quality clinical or research outcomes.

What are the main challenges a director variant analyst faces when leading a genomics team?

A Director Variant Analyst often navigates challenges such as managing diverse teams of bioinformaticians and geneticists, ensuring data accuracy amidst rapidly evolving technologies, and balancing project deadlines with regulatory compliance. They must facilitate effective communication between research, clinical, and IT departments, especially when interpreting and reporting complex genomic data. Additionally, staying current with advancements in variant interpretation and integrating new tools while maintaining operational efficiency is a key aspect of the role.

What is the difference between Director Variant Analyst vs Variant Analyst?

AspectDirector Variant AnalystVariant Analyst
CredentialsBachelor's degree, often with experience in data analysis or geneticsBachelor's or higher in biology, genetics, or related field
Work EnvironmentLeadership role in labs or healthcare companies, overseeing projectsHands-on data analysis in labs or research settings
Industry UsageUsed in biotech, healthcare, and research organizationsCommon in genetics labs, research institutions, and healthcare

The main difference is that the Director Variant Analyst typically holds a leadership position with strategic responsibilities, while the Variant Analyst focuses on data analysis and research tasks. Both roles require relevant credentials and are integral to genetics and healthcare industries, but the Director role involves overseeing teams and projects.

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Director Variant Analyst jobs near you
Infographic showing various Director Variant Analyst job openings in the United States as of August 2026, with employment types broken down into 2% As Needed, 83% Full Time, 12% Part Time, 1% Temporary, and 2% Contract. Highlights an 91% Physical, 3% Hybrid, and 6% Remote job distribution.

Associate Laboratory Director

Natera

San Carlos, CA • On-site

$128K - $167K/yr

Part-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted yesterday

Natera rating

7.7

Company rating: 7.7 out of 10

Based on 38 frontline employees who took The Breakroom Quiz

57th of 120 rated laboratories

Job description

As the Associate/Laboratory Director, you have clinical oversight of Natera's laboratory testing. You ensure that testing is properly performed, and applicable regulatory standards are met. You are responsible for ensuring that the laboratory implements testing while consistently providing accurate and reliable patient test results.
PRIMARY RESPONSIBILITIES:
  • Review, approve, and sign-out reports for a variety of clinical molecular/cytogenetic and/or oncologic results, including NIPT, carrier screening, PGD/PGS, products of conception and rare disease testing on platforms including SNP array analysis, NGS, and other methodologies.
  • Oversee the review of genetic and CNV variant data: interpret NGS and microarray results in the context of medical literature, online variant databases and other references along with relevant patient demographic data.
  • Provide clinical and technical support for genetic counselors and other laboratory personnel.
  • Set standards for laboratory testing and acceptable levels of analytic performance and ensure these are maintained.
  • Analyze lab data, contribute to or write publications for high-quality scientific journals.
  • May serve as Technical Supervisor. The Technical Supervisor is responsible for ensuring: appropriate test method selection; adequate method verification to determine the accuracy and precision of the test; enrollment of the laboratory in a CMS-approved proficiency testing (PT) program for the test performed; PT samples are tested in accordance with the CLIA requirements; PT results are returned within the time frames established by the PT program; PT reports are reviewed by the appropriate staff; corrective action plans are followed when PT results are found to be unacceptable or unsatisfactory; quality assessment and quality control programs are established and maintained; acceptable analytical test performance is established and maintained for each test system; remedial actions are taken and documented when significant deviations from the laboratory's established performance characteristics are identified, and patient test results are reported only when the system is functioning properly; personnel have been appropriately trained and demonstrate competency prior to testing patient specimens; policies and procedures are established for monitoring personnel competency in all phases (preanalytic, analytic, and postanalytic) of testing to assure the ongoing competency of all individuals who perform testing; remedial training or continuing education needs are identified, and training provided; and an approved procedure manual is available to all personnel.
  • Manage a team: review and approve assigned work; mentor and develop personnel, including dedicated succession planning and contingency management.
  • This role works with PHI on a regular basis both in paper and electronic form and has an access to various technologies to access PHI (paper and electronic) in order to perform the job.
  • Employee must complete training relating to HIPAA/PHI privacy, General Policies and Procedure Compliance training and security training as soon as possible but not later than the first 30 days of hire.
  • Must maintain a current status on Natera training requirements.

QUALIFICATIONS:
  • MD/DO and/or PhD in genetics or related field required.
  • Current California license/eligibility as a Clinical Genetic Molecular Biologist Scientist required.
  • ABMGG board-certified/eligible in Clinical Cytogenetics and/or Molecular Genetics.
  • Current Certificate of Qualification in Genetic Testing from the NYS CLEP preferred.
  • 2 or more years of experience in a CLIA-certified clinical laboratory setting analyzing, interpreting and reporting clinical genetic/genomic data.
  • Knowledge of CAP, CLIA, California, and New York state regulations.
  • Management experience required.

KNOWLEDGE, SKILLS, AND ABILITIES:
  • Excellent written and oral communication skills.
  • Experience leading a laboratory offering prenatal screening and evaluating, interpreting, and reporting out NGS and microarray data.
  • Familiarity with next-generation sequencing, and/or knowledge of advanced methods of copy number detection.
  • Strong background in human and medical genetics, and oncology with a familiarity of online human genomic databases and variant interpretation resources (e.g., ClinVar, gnomAD, OMIM, ClinGen)
  • Understanding of statistical measures utilized in genetic testing and screening.

Must be able to discern color visually [or be able to evaluate cellular morphology when applicable] and pass applicable screening assessment
Compensation & Total Rewards
This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.
This position is also eligible for additional compensation and benefits through Natera's robust Total Rewards program, including:
  • Annual performance incentive bonus
  • Long-term equity awards
  • Comprehensive health benefits (medical, dental, vision)
  • 401(k) with company match
  • Generous paid time off and company holidays
  • Additional wellness and work-life benefits

Compensation Range
$142,200-$177,750 USD
OUR OPPORTUNITY
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women's health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you'll work hard and grow quickly. Working alongside the elite of the industry, you'll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
If you are based in California, we encourage you to read this important information for California residents.
Link: https://www.natera.com/notice-of-data-collection-california-residents/
Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.
For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page

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