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Director Variant Analyst Jobs in Washington (NOW HIRING)

Biologist

Baltimore, MD ยท On-site

Variant calling and basic annotation and DNA methylation data processing and analysis and Data integration across datasets when directed Prepares, organizes and maintains various lab samples ...

Biologist

Baltimore, MD

$85K - $135K/yr

Variant calling and basic annotation and DNA methylation data processing and analysis and Data integration across datasets when directed Prepares, organizes and maintains various lab samples ...

... Research (DIR), Research Technologies Branch (RTB), Integrated Data Sciences Section (IDSS) in ... Provide bioinformatics support to include somatic and germline variant calling and analysis, single ...

... Research (DIR), Research Technologies Branch (RTB), Integrated Data Sciences Section (IDSS) in ... Provide bioinformatics support to include somatic and germline variant calling and analysis, single ...

... Research (DIR), Research Technologies Branch (RTB), Integrated Data Sciences Section (IDSS) in ... Provide bioinformatics support to include somatic and germline variant calling and analysis, single ...

Director Variant Analyst information

What are the key skills and qualifications needed to thrive as a director variant analyst, and why are they important?

To thrive as a Director Variant Analyst, you need advanced expertise in genomics, variant interpretation, and bioinformatics, often supported by a PhD or equivalent experience in genetics or molecular biology. Familiarity with next-generation sequencing (NGS) platforms, variant annotation tools, and clinical databases, along with relevant certifications such as board certification in clinical molecular genetics, is highly valued. Strong leadership, decision-making, and communication skills are critical for managing teams and collaborating across departments. These competencies ensure accurate and efficient analysis of genetic data, drive innovation, and support high-quality clinical or research outcomes.

What is a director variant analyst?

A Director Variant Analyst is a senior professional responsible for overseeing the analysis and interpretation of genetic variants within an organization, typically in a clinical or research genetics setting. They lead teams that evaluate genetic data to determine the clinical significance of DNA sequence variations, which is crucial for diagnosing genetic disorders or informing personalized medicine. The director collaborates with scientists, clinicians, and laboratory staff to ensure the accuracy and quality of genetic variant analysis and reporting. They may also contribute to the development of protocols, implementation of new technologies, and compliance with industry regulations. This role requires deep expertise in genetics, bioinformatics, and leadership.

What is the difference between Director Variant Analyst vs Variant Analyst?

AspectDirector Variant AnalystVariant Analyst
CredentialsBachelor's degree, often with experience in data analysis or geneticsBachelor's or higher in biology, genetics, or related field
Work EnvironmentLeadership role in labs or healthcare companies, overseeing projectsHands-on data analysis in labs or research settings
Industry UsageUsed in biotech, healthcare, and research organizationsCommon in genetics labs, research institutions, and healthcare

The main difference is that the Director Variant Analyst typically holds a leadership position with strategic responsibilities, while the Variant Analyst focuses on data analysis and research tasks. Both roles require relevant credentials and are integral to genetics and healthcare industries, but the Director role involves overseeing teams and projects.

What are the main challenges a director variant analyst faces when leading a genomics team?

A Director Variant Analyst often navigates challenges such as managing diverse teams of bioinformaticians and geneticists, ensuring data accuracy amidst rapidly evolving technologies, and balancing project deadlines with regulatory compliance. They must facilitate effective communication between research, clinical, and IT departments, especially when interpreting and reporting complex genomic data. Additionally, staying current with advancements in variant interpretation and integrating new tools while maintaining operational efficiency is a key aspect of the role.
What are the most commonly searched types of Variant Analyst jobs in Washington? The most popular types of Variant Analyst jobs in Washington are:
What job categories do people searching Director Variant Analyst jobs in Washington look for? The top searched job categories for Director Variant Analyst jobs in Washington are:
What cities in Washington are hiring for Director Variant Analyst jobs? Cities in Washington with the most Director Variant Analyst job openings:
Infographic showing various Director Variant Analyst job openings in Washington as of July 2026, with employment types broken down into 100% Full Time. Highlights an 82% In-person, and 18% Remote job distribution.

Technical Intelligence & Advanced Sensing

Mission One

Washington, DC โ€ข On-site

$100K - $160K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 7 days ago


Job description

Benefits:
  • 401(k) matching
  • Bonus based on performance
  • Dental insurance
  • Health insurance
  • Opportunity for advancement
  • Paid time off
  • Training & development
  • Vision insurance

Position Overview
Mission One is seeking a Technical Intelligence Analyst to support advanced technical and intelligence production across SIGINT, ELINT, MASINT, and TECHINT mission areas. This role is ideal for analysts with deep technical curiosity and operational rigor-professionals who understand how systems and sensors work and can translate technical signatures into clear intelligence judgments. This position may supports high-priority missions such as threat characterization, targeting support, collection optimization, and technical risk analysis.
Key Responsibilities
  • Perform advanced analysis of signals, emissions, and technical phenomena
  • Characterize adversary sensors, emitters, and weapon systems based on technical signatures
  • Translate complex technical findings into intelligence assessments and operational reporting
  • Support targeting, collection optimization, and capability assessments
  • Contribute to technical threat models, risk analysis, and adversary system profiling
  • Collaborate with multi-INT teams to drive integrated, actionable products for customers
  • Produce and brief technical intelligence to both technical and non-technical stakeholders

Required Qualifications (Baseline)
  • Active security clearance
  • Bachelor's degree in a STEM discipline (engineering, physics, computer science, math, etc.) or equivalent technical intelligence experience
  • 3+ years of experience in SIGINT/ELINT/MASINT/TECHINT exploitation or analysis
  • Strong ability to communicate complex technical information clearly and concisely
  • Demonstrated experience with operational reporting and technical intelligence standards
  • Strong writing skills with the ability to produce customer-facing intelligence products

Preferred Qualifications
  • Experience with DoD/IC technical systems and workflows
  • Exposure tosystems engineering, electronic warfare (EW/ESM), ISR payload operations, or sensor integration
  • Familiarity with technical libraries/databases and standardized reporting formats
  • Experience supporting:
    • Technical targeting / collection planning
    • Threat modeling and capability assessments
    • Advanced emitter or sensor profiling

Typical Deliverables
  • Technical Intelligence Reports (TIRs)
  • Signal and phenomenology characterization products
  • Sensor/emitter profiles and technical baselines
  • Capability assessments and system risk analysis
  • Technical threat models and adversary system breakdowns

Best Fit Role Profiles
We will consider candidates aligned with one or more of the following:
  • Technical SIGINT Analyst
  • SIGINT Analyst (engineering-adjacent)
  • ELINT Analyst
  • MASINT Analyst
  • TECHINT Analyst
  • Weapons Systems Analyst (technical variant)
  • Missiles Systems Analyst (technical variant)
  • Space / Counterspace Analyst (technical variant)
  • Other similarly aligned skills.

Compensation: $100,000.00 - $160,000.00 per year
Mission One - Where People Matter
As a national security, information technology, and intelligence-focused organization at Mission One, we seek to push the boundaries of innovation to produce cutting-edge defense and intelligence tools that address current and emerging national security threats.
Our expertise in defense contracting allows us to harness the transformative power of advanced technology. Through this combination, we bring situational awareness to the next level, forging intelligent support capabilities and fortifying critical infrastructure like never before. Working closely with esteemed government partners, we tackle constantly evolving security challenges head-on. Our secure and scalable solutions instill unwavering safety and resilience in our nation.
Careers at Mission One
To explore career opportunities with Mission One, simply send our team your most up-to-date resume and highlight your interests and areas of expertise. If your skills and interests align with our openings, our team will reach out to you to discuss potential opportunities.
Key Considerations for a Career in National Security
Meeting Qualifications
Joining a team that contributes to national security efforts typically requires meeting specific qualifications, such as educational background, security clearances, and relevant experience. Each organization or agency may have its own specific requirements and application processes.
Impact and Purpose
Working in national security allows you to have a direct impact on the protection and well-being of your country and its citizens. Your efforts can help prevent potential threats and contribute to the safety and security of your nation.
Diverse Career Opportunities
National security offers a wide range of career paths to suit different skills, backgrounds, and interests. Whether you're excited about intelligence analysis, cybersecurity, law enforcement, diplomacy, or emergency management, the national security field has various roles available.
Continuous Learning and Development
National security is an ever-evolving field. Joining a national security-focused organization often means engaging in ongoing training and professional development to stay up-to-date on new threats, technologies, and strategies. This continuous learning provides intellectual stimulation and helps you develop valuable skills throughout your career.
Collaborative Work Environment
National security efforts require collaboration and teamwork. As a part of our team, you'll have the opportunity to work alongside professionals from diverse backgrounds, including government agencies, military personnel, intelligence analysts, law enforcement agencies, and private sector organizations. This collaborative environment promotes the exchange of knowledge, expertise, and innovative ideas.
High-Stakes Challenges
National security work often involves complex and high-stakes challenges. As a member of our team, you may be tasked with analyzing intelligence, identifying vulnerabilities, formulating strategies, responding to crises, or developing new technologies. The fast-paced nature of the work provides a sense of purpose and excitement as you tackle important issues.
Professional Growth and Advancement
A career in national security offers opportunities for professional growth and advancement. As you gain experience and expertise, you'll have the chance to take on leadership roles, work on specialized projects, or pursue advanced positions within our organization or the broader national security community.
Job Security
National security is a vital and enduring aspect of a nation's stability. As a result, there is often a demand for skilled professionals in this field, providing a level of job security and stability.
Commitment to Ethical Practices
At Mission One, we are committed to upholding ethical standards, respecting civil liberties, and ensuring the protection of individual rights. These principles guide our decision-making process and promote accountability within the field.