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Director Clinical Transformation Jobs in Reston, VA

AstraZeneca

Evinova Product Director

Gaithersburg, MD · On-site

$251K - $263K/yr

... digital transformation across the life sciences sector. By combining science-based expertise ... Maintain a sharp point of view on the evolving clinical trial and AI landscape-proactively ...

New

AstraZeneca

Evinova Product Director

Gaithersburg, MD · On-site

$251K - $263K/yr

... digital transformation across the life sciences sector. By combining science-based expertise ... Maintain a sharp point of view on the evolving clinical trial and AI landscape-proactively ...

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All JobsClinical Transformation JobsDirector Clinical Transformation JobsDirector Clinical Transformation Jobs in Reston, VA

Director Clinical Transformation information

See Reston, VA salary details

$53.6K

$104.2K

$173.7K

How much do director clinical transformation jobs pay per year?

As of Aug 10, 2026, the average yearly pay for director clinical transformation in Reston, VA is $104,165.00, according to ZipRecruiter salary data. Most workers in this role earn between $83,200.00 and $113,400.00 per year, depending on experience, location, and employer.

What is a director clinical transformation?

A Director of Clinical Transformation leads initiatives to improve healthcare quality, efficiency, and patient outcomes by implementing innovative processes, technologies, and best practices. They collaborate with clinical and administrative teams to drive organizational change, enhance care delivery models, and ensure alignment with regulatory standards. This role requires expertise in healthcare operations, data analytics, and change management to support continuous improvement efforts and optimize patient care.

What are the typical challenges faced by a director clinical transformation, and how do they impact daily work?

Directors of Clinical Transformation often encounter challenges such as resistance to change among clinical staff, aligning diverse stakeholders on new processes, and integrating new technologies into existing workflows. These challenges require strategic planning, effective change management techniques, and ongoing communication to ensure buy-in across departments. On a daily basis, you may need to facilitate meetings, troubleshoot implementation issues, and measure progress against performance metrics. Successfully navigating these obstacles supports smoother clinical operations and better patient outcomes, making the role both demanding and highly impactful.

What are the key skills and qualifications needed to thrive in the director clinical transformation position, and why are they important?

To thrive as a Director Clinical Transformation, you need deep experience in healthcare operations, project management, process improvement methodologies (such as Lean or Six Sigma), and a relevant advanced degree in nursing, healthcare administration, or a related field. Familiarity with healthcare IT systems, EHR platforms, data analytics tools, and certifications like PMP or CPHQ are often important. Outstanding leadership, strategic thinking, change management, and communication skills help you drive large-scale transformation initiatives and engage multidisciplinary teams. These competencies are crucial for successfully navigating the complexities of clinical practice while implementing sustainable improvements that enhance patient care and operational efficiency.

What are popular job titles related to Director Clinical Transformation jobs in Reston, VA? For Director Clinical Transformation jobs in Reston, VA, the most frequently searched job titles are:
What job categories do people searching Director Clinical Transformation jobs in Reston, VA look for? The top searched job categories for Director Clinical Transformation jobs in Reston, VA are:
What cities near Reston, VA are hiring for Director Clinical Transformation jobs? Cities near Reston, VA with the most Director Clinical Transformation job openings:
Director Clinical Transformation jobs near you
Infographic showing various Director Clinical Transformation job openings in Reston, VA as of August 2026, with employment types broken down into 2% As Needed, 73% Full Time, 19% Part Time, and 6% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $104,165 per year, or $50.1 per hour.

Director, Digital Business Partner

AstraZeneca

Gaithersburg, MD • On-site

$153K - $229K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 10 days ago

AstraZeneca rating

8.4

Company rating: 8.4 out of 10

Based on 45 frontline employees who took The Breakroom Quiz

22nd of 86 rated pharmaceutical

Job description

AstraZeneca is seeking an innovative technology leader to drive the digital transformation of the Cell Therapy Technical Operation organization.
As Director - Digital Business Partner, you will champion the adoption of advanced digital platforms, intelligent automation, and enterprise systems to enable scalable, data-driven operations, delivering measurable value across the cell therapy value chain and transforming the patient and customer journey into alignment with AstraZeneca's Cell Therapy Ambition. You will report to the Executive Director, Head of Operation Cell Therapy IT and will be based in Gaithersburg or Rockville, MD.
Responsibilities:
1. Innovation in Business Systems
  • System Integration: Serve as the IT partner lead with deep technical expertise for strategic enterprise platforms including SAP, MES, LIMS, Advanced Planning Systems, and Digital Cell orchestration systems, ensuring seamless interoperability and AI-readiness.
  • Process Digitization: Collaborate with Cell Therapy business leads to define requirements and deliver foundational to advanced digital solutions across the cell therapy value chain Strategy, Planning, Scheduling, Slot Management, Procurement, Manufacturing, and Vein-to-Vein Logistics.
  • Data Management & Governance: Collaborate with IT to implement modern data infrastructure, ensuring robust data privacy, integrity, and accessibility across digital platforms and AI models.

2. Digital & IT Strategy Leadership
  • Enterprise IT Alignment: Lead a talented team and partner closely with global IT, digital, and data teams to define and execute a cohesive digital transformation roadmap aligned with business and technology strategies across clinical and commercial operations.
  • AI Strategy & Use Case Development: Lead the identification and operationalization of AI and digital applications that drive predictive analytics, intelligent planning, supply chain optimization, manufacturing insights, and personalized therapy orchestration. the identification and operationalization of AI/ML applications that drive predictive analytics, intelligent planning, supply chain optimization, manufacturing insights, and personalized therapy orchestration.
  • Technology Vision: Establish a future-ready vision for digitally enabled business processes- leveraging AI, cloud platforms, and advanced data architectures to unlock productivity and scalability across manufacturing, supply chain and Quality Organization.

3. Program Execution & Change Leadership
  • Transformation Leadership: Drive cross-functional digital transformation initiatives, managing scope, budgets, schedules, and outcomes while delivering measurable business value
  • Customer Experience: Redesign digital touchpoints to enhance the experience for patients, physicians, and commercial partners through intelligent orchestration platforms and automation.

Skills & Experience:
  • 14+ years of professional experience with a BS/BA (or 12+ with MS/MA/MBA) in Engineering, Computer Science, Information Systems, Supply Chain, or a related technical field.
  • Proven practical experience designing and architecting enterprise platforms, and leading technical teams to implement systems such as MES, LIMS, SAP, and Salesforce-based workflow platforms.
  • Solid understanding of modern AI technologies and practical application of these technologies in biopharma or manufacturing environments; experience in the pharmaceutical industry is a plus.
  • Strong hands-on understanding of Cell therapy operations, including manufacturing, supply chain, and quality systems within regulated environments.
  • Hands-on experience applying Generative AI and Agentic AI to accelerate the product and software lifecycle (e.g., requirements generation, user story development, automated test creation, anomaly detection, and release risk insights) is highly desirable.
  • Track record of leading high-caliber technical teams, shaping IT strategy, and delivering enterprise systems and AI-driven capabilities within life sciences or other highly regulated industries.
  • Strategic and execution-focused leader who can translate operational needs into scalable technical solutions while collaborating effectively across engineering, manufacturing, quality, and business teams.

#CellTherapy
The annual base pay for this position ranges from $153K to $229K. Our positions offer eligibility for various incentives-an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Date Posted
03-Aug-2026
Closing Date
17-Aug-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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