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Director Clinical Operations Jobs in San Ramon, CA

Olema Oncology

Director, Clinical Science

San Francisco, CA · On-site

$220K - $250K/yr

About the Role >>> Director, Clinical Science As the Director, Clinical Science reporting to the ... You will work collaboratively in a multi-disciplinary team setting including Clinical Operations ...

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Director Clinical Operations information

See San Ramon, CA salary details

$67.1K

$163.1K

$315.7K

How much do director clinical operations jobs pay per year?

As of Aug 18, 2026, the average yearly pay for director clinical operations in San Ramon, CA is $163,123.00, according to ZipRecruiter salary data. Most workers in this role earn between $114,000.00 and $193,900.00 per year, depending on experience, location, and employer.

What does a director of clinical operations do?

A director of clinical operations manages the daily operations of a healthcare facility or a specific department within a clinic or hospital. As a director of clinical operations, your responsibilities include scheduling staff to ensure proper coverage of patients and overseeing the productivity of your team to meet the organization's expectations. You define policies and procedures, facilitating further training when necessary. The director of clinical operations must also assess the performance of the medical team under your supervision regularly and mainstream processes when possible. Medical device manufacturers and pharmaceutical companies often hire a director of clinical operations to oversee research, lab, and testing operations.

What does a director of clinical operations do?

A Director of Clinical Operations is responsible for overseeing the day-to-day management and strategic direction of clinical trials and research activities within healthcare organizations or pharmaceutical companies. They ensure that clinical studies are conducted efficiently, ethically, and in compliance with regulatory requirements. This role involves supervising teams, managing budgets, developing protocols, and liaising with stakeholders to ensure successful trial outcomes. Directors of Clinical Operations play a crucial role in bringing new medical treatments to market by ensuring studies run smoothly from start to finish.

What are the key skills and qualifications needed to thrive as a director of clinical operations?

To thrive as a Director of Clinical Operations, you need a robust background in clinical management, regulatory compliance, and healthcare administration, often supported by a relevant degree and substantial leadership experience. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and certifications like PMP or CCRA are commonly required. Exceptional leadership, strategic thinking, and communication skills help drive teams, manage stakeholders, and oversee complex projects. These skills are critical for ensuring clinical programs run efficiently, meet regulatory standards, and deliver high-quality patient outcomes.

How does a director of clinical operations typically collaborate with cross-functional teams to ensure successful clinical trial execution?

A Director of Clinical Operations regularly collaborates with cross-functional teams such as regulatory affairs, data management, medical affairs, and biostatistics to ensure clinical trials are executed on time, within budget, and in compliance with regulations. This role involves leading team meetings, aligning project timelines, and facilitating communication between internal stakeholders and external partners like CROs and vendors. Strong coordination skills are essential, as the Director must balance diverse priorities and resolve any operational issues that arise, ensuring all teams work toward shared objectives.

What is the difference between Director Clinical Operations vs Clinical Project Manager?

AspectDirector Clinical OperationsClinical Project Manager
CredentialsTypically requires advanced degrees (e.g., MS, PhD) and extensive industry experienceUsually holds a bachelor's or master's degree in a related field, with relevant project management certifications
Work EnvironmentOversees multiple projects and teams across departments, strategic planningManages individual clinical trials, coordinates project activities, and timelines
Employer & Industry UsageUsed in pharmaceutical, biotech, and healthcare companies for senior leadership rolesCommonly employed in clinical research organizations and pharmaceutical companies for trial management

The main difference is that the Director Clinical Operations focuses on strategic oversight and leadership across multiple clinical trials, while the Clinical Project Manager handles the day-to-day management of specific clinical studies. Both roles require strong industry knowledge, but the director position involves broader responsibilities and higher-level decision-making.

Is a director of clinical operations a high position?

A director of clinical operations is a senior leadership role responsible for overseeing clinical trial activities, managing teams, and ensuring regulatory compliance. It is considered a high-level position within the healthcare and pharmaceutical industries, often requiring extensive experience and strategic skills.
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Director Clinical Operations jobs near you
Infographic showing various Director Clinical Operations job openings in San Ramon, CA as of August 2026, with employment types broken down into 1% As Needed, 83% Full Time, 11% Part Time, 1% Temporary, 3% Contract, and 1% Nights. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $163,123 per year, or $78.4 per hour.

Assoc Director, Clinical Operations-Early Phase

Gilead

Foster City, CA • On-site

Full-time

Medical, Dental, Vision, Life, PTO

This job post has expired today. Applications are no longer accepted.

Gilead Sciences rating

8.9

Company rating: 8.9 out of 10

Based on 12 frontline employees who took The Breakroom Quiz

9th of 86 rated pharmaceutical

Job description

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.

Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.
Job Description

The Associate Director, Clinical Operations is a key leadership role responsible for strategic planning, execution, and oversight of complex early-phase clinical trials and/or programs. This individual is accountable for operational delivery, financial stewardship, quality, compliance, timelines, and budget performance.

This role operates at the program level, influencing cross-functional strategy, advancing operational innovation, and driving excellence across Clinical Operations. The position may include direct people management responsibilities or operate as a senior individual contributor, depending on business needs.

Responsibilities:

  • Lead execution of complex early-phase studies and/or multiple studies within a program, from planning through closeout.
  • Provide operational oversight to ensure delivery against timelines, budgets, quality standards, and regulatory requirements.
  • Drive program-level strategy, including study design input, feasibility, risk mitigation, resource planning, and execution planning.
  • Accountable for study and program financial management, including forecasting, budget oversight, and resource allocation.
  • Partner with Clinical Development, Clinical Pharmacology, Research, Regulatory, Biometrics, and other functions to align and deliver program objectives.
  • Lead CRO/CRU/vendor selection, contract negotiations, and ongoing performance management.
  • Influence program and organizational decision-making through operational expertise and data-driven insights.
  • Lead or contribute to cross-functional and organizational initiatives, including transformation, change management, and continuous improvement efforts.
  • Serve as a subject matter expert or Business Process Owner for Clinical Operations processes, SOPs, tools, and systems.
  • Proactively identify study and program risks and implement mitigation strategies.
  • Ensure compliance with global regulatory requirements, including FDA, EMA, ICH-GCP, and internal SOPs.
  • Demonstrate leadership through influence across internal and external stakeholders.
  • people manager responsibilities apply:
  • Lead, mentor, and develop clinical operations staff, fostering a high-performance and inclusive culture.
  • Provide coaching, feedback, and career development planning aligned with organizational goals.
  • Empower teams through clear goal-setting, accountability, and removal of operational barriers.
  • Oversee inspection readiness and support audit activities as needed.

Basic qualifications:

  • Bachelor's degree (or RN) with10+ yearsof relevant clinical research or life sciences experience, OR
  • Advanced degree (MS, MA, PharmD, PhD, MBA) with8+ yearsof relevant experience.
  • Demonstrated experience leading complex clinical trials and/or programs.
  • Strong knowledge of global clinical regulations (FDA, EMA), ICH-GCP, and clinical trial processes.

Preferred qualifications:

  • Experience in early-phase clinical development.
  • Proven ability to lead cross-functional teams and influence without authority.
  • Experience with CRO/vendor sourcing and oversight.
  • Strong strategic thinking and ability to connect operational execution with broader business objectives.
  • Demonstrated experience with process improvement, innovation, or operational transformation initiatives.
  • Excellent communication, collaboration, and stakeholder management skills.
  • Ability to manage complexity, prioritize competing demands, and deliver results in a fast-paced environment.
  • When needed, ability to travel.

People Leader Accountabilities:

  • Create Inclusion - knowing the business value of diverse teams, modeling inclusion, and embedding the value of diversity in the way they manage their teams.
  • Develop Talent - understand the skills, experience, aspirations and potential of their employees and coach themoncurrent performance and future potential. They ensure employees are receivingthe feedbackand insight needed to grow, develop and realize their purpose.
  • Empower Teams - connect the team to the organization by aligning goals, purpose, and organizational objectives, and holding them to account. They provide the support needed to remove barriers and connect their team to the broader ecosystem.


The salary range for this position is: $195,670.00 - $253,220.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

https://www.gilead.com/careers/compensation-benefits-and-wellbeing

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.


For jobs in the United States:

Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability,genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.comfor assistance.


For more information about equal employment opportunity protections, please view the'Know Your Rights' poster.

NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT


Gilead Sciences will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law.

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.


Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.


For Current Gilead Employees and Contractors:

Please apply via the Internal Career Opportunities portal in Workday.

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