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Director Clinical Operations Jobs in San Ramon, CA

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Director Clinical Operations information

See San Ramon, CA salary details

$67.1K

$163.1K

$315.7K

How much do director clinical operations jobs pay per year?

As of Aug 18, 2026, the average yearly pay for director clinical operations in San Ramon, CA is $163,123.00, according to ZipRecruiter salary data. Most workers in this role earn between $114,000.00 and $193,900.00 per year, depending on experience, location, and employer.

What does a director of clinical operations do?

A director of clinical operations manages the daily operations of a healthcare facility or a specific department within a clinic or hospital. As a director of clinical operations, your responsibilities include scheduling staff to ensure proper coverage of patients and overseeing the productivity of your team to meet the organization's expectations. You define policies and procedures, facilitating further training when necessary. The director of clinical operations must also assess the performance of the medical team under your supervision regularly and mainstream processes when possible. Medical device manufacturers and pharmaceutical companies often hire a director of clinical operations to oversee research, lab, and testing operations.

What does a director of clinical operations do?

A Director of Clinical Operations is responsible for overseeing the day-to-day management and strategic direction of clinical trials and research activities within healthcare organizations or pharmaceutical companies. They ensure that clinical studies are conducted efficiently, ethically, and in compliance with regulatory requirements. This role involves supervising teams, managing budgets, developing protocols, and liaising with stakeholders to ensure successful trial outcomes. Directors of Clinical Operations play a crucial role in bringing new medical treatments to market by ensuring studies run smoothly from start to finish.

What are the key skills and qualifications needed to thrive as a director of clinical operations?

To thrive as a Director of Clinical Operations, you need a robust background in clinical management, regulatory compliance, and healthcare administration, often supported by a relevant degree and substantial leadership experience. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and certifications like PMP or CCRA are commonly required. Exceptional leadership, strategic thinking, and communication skills help drive teams, manage stakeholders, and oversee complex projects. These skills are critical for ensuring clinical programs run efficiently, meet regulatory standards, and deliver high-quality patient outcomes.

How does a director of clinical operations typically collaborate with cross-functional teams to ensure successful clinical trial execution?

A Director of Clinical Operations regularly collaborates with cross-functional teams such as regulatory affairs, data management, medical affairs, and biostatistics to ensure clinical trials are executed on time, within budget, and in compliance with regulations. This role involves leading team meetings, aligning project timelines, and facilitating communication between internal stakeholders and external partners like CROs and vendors. Strong coordination skills are essential, as the Director must balance diverse priorities and resolve any operational issues that arise, ensuring all teams work toward shared objectives.

What is the difference between Director Clinical Operations vs Clinical Project Manager?

AspectDirector Clinical OperationsClinical Project Manager
CredentialsTypically requires advanced degrees (e.g., MS, PhD) and extensive industry experienceUsually holds a bachelor's or master's degree in a related field, with relevant project management certifications
Work EnvironmentOversees multiple projects and teams across departments, strategic planningManages individual clinical trials, coordinates project activities, and timelines
Employer & Industry UsageUsed in pharmaceutical, biotech, and healthcare companies for senior leadership rolesCommonly employed in clinical research organizations and pharmaceutical companies for trial management

The main difference is that the Director Clinical Operations focuses on strategic oversight and leadership across multiple clinical trials, while the Clinical Project Manager handles the day-to-day management of specific clinical studies. Both roles require strong industry knowledge, but the director position involves broader responsibilities and higher-level decision-making.

Is a director of clinical operations a high position?

A director of clinical operations is a senior leadership role responsible for overseeing clinical trial activities, managing teams, and ensuring regulatory compliance. It is considered a high-level position within the healthcare and pharmaceutical industries, often requiring extensive experience and strategic skills.
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Director Clinical Operations jobs near you
Infographic showing various Director Clinical Operations job openings in San Ramon, CA as of August 2026, with employment types broken down into 1% As Needed, 83% Full Time, 11% Part Time, 1% Temporary, 3% Contract, and 1% Nights. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $163,123 per year, or $78.4 per hour.

Associate Director, Clinical Operations

Dispatch Bio

San Francisco, CA • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 6 days ago

Job description

About us:
Our purpose at Dispatch is to help create a world where all cancer patients can be cured. We're humbled by the opportunity to work together as a team on some of the most pressing medical challenges of our time.
To achieve our purpose, we are dedicated to engineering a universal treatment across solid tumors. We're committed to the development of novel therapies, leveraging first-in-class technologies in viral vectors, universal targets, and novel cytokine biology. Our therapeutic approach has the potential to enable us to treat significant numbers of cancer patients and make a real and lasting impact on the world.
Our company was founded on pioneering work carried out in the laboratories of Dr. Carl June (University of Pennsylvania), Dr. Kole Roybal (University of California, San Francisco), Dr. Christopher Garcia (Stanford University) and Dr. Andy Minn (Memorial Sloan Kettering Cancer Center).
At our company, you would become one of our early team members- not only playing a role in meeting our ambitious mission but also building our thriving culture. We are determined to deliver with urgency to discover new solutions and we always stay dedicated to scientific rigor; we have an ownership mindset because each and every one of us is integral to our success. Collaboration is core for us because we believe that by bringing people together with diverse perspectives, we make a stronger whole. And, we show we care about our work and each other by sharing feedback - ultimately in service of our vision to empower people to continue forward with their lives - cancer free.
The role:
The Associate Director, Clinical Operations will play a critical role in the planning, execution, and oversight of Dispatch's early-phase (Phase I/II) oncology clinical trials. Reporting to the Vice President of Clinical Operations, this person will partner closely with Clinical Development, Regulatory Affairs, Biostatistics, Drug Supply, and Quality Assurance internally, as well as with CROs, central labs, and other clinical trial vendors externally, to ensure our studies are executed with the highest standards of quality, timeliness, and regulatory compliance.
Key responsibilities:
  • Lead the operational execution of one or more early-phase (Phase I/II) oncology clinical trials, from study start-up through close-out
  • Serve as the primary operational point of contact for CROs, vendors, and investigative sites, ensuring deliverables are met on time, within budget, and to quality standards
  • Develop and manage study timelines, budgets, and risk mitigation plans; proactively identify and resolve issues that could impact trial timelines or data integrity
  • Oversee site selection, activation, and ongoing site management activities in partnership with CROs and the broader Clinical Operations team
  • Collaborate with Clinical Development and Biostatistics to develop and review protocols, informed consent forms, case report forms, and other essential study documents
  • Manage vendor oversight activities, including central labs, IRT, imaging, and other specialty vendors supporting early-phase oncology trials
  • Partner with Drug Supply/CMC teams to ensure adequate investigational product supply and accurate demand forecasting
  • Monitor trial enrollment, data quality, and safety reporting in collaboration with Pharmacovigilance and Medical Monitoring
  • Contribute to the development of departmental SOPs, working practices, and process improvements as Dispatch's clinical operations function scales
  • Support inspection readiness activities and ensure trials are conducted in accordance with ICH-GCP, FDA regulations, and Dispatch quality standards
  • Prepare and present study status updates to internal stakeholders and senior leadership

Required experience & skills:
  • Bachelor's degree required; advanced degree (e.g., MS, RN, PharmD) in a life sciences or related field preferred
  • Minimum of 7 years of progressive clinical operations experience in the biotechnology or pharmaceutical industry
  • Demonstrated experience managing early-phase (Phase I/II) oncology clinical trials, including study start-up, site management, and vendor oversight
  • Strong working knowledge of ICH-GCP guidelines, FDA regulations, and clinical trial operational best practices
  • Experience managing CROs and other third-party vendors, including budget and contract oversight
  • Proficiency with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and other clinical trial software
  • Collaborative nature, geared toward cross-functional teamwork
  • Excellent organizational, problem-solving, and time management skills
  • Positive attitude, dedicated work ethic, and flexible orientation for operating in a fast-paced, entrepreneurial environment
  • Strong verbal and written communication skills, with the ability to translate complex clinical information for diverse audiences
  • Demonstrated leadership skills, including the ability to manage a clinical operations team, communicate, coach, mentor, and develop employees
  • Ability to be onsite 4 days per week
  • Ability to travel up to 20%, if needed

Preferred experience & skills:
  • Experience with cell and gene therapy, personalized medicine, or other biologics clinical trials
  • Prior experience working in a small or growth-stage biotech environment
  • Experience supporting regulatory submissions (e.g., IND filings, IB updates) or inspection readiness activities
  • Established relationships with CROs and vendors specializing in oncology and/or cell therapy trials
  • People management experience, with a track record of developing and mentoring clinical operations staff

Our values:
Our values guide everything we do. While capabilities and skills are vital, understanding how a potential new colleague would embody our values is central to our hiring decisions.
Determined to deliver:
By working with focus and passion, we can provide patients with the solutions they need.
Own every outcome:
We can reach new heights when we stay centered on our shared success.
Collaboration at the core:
When we band together, our work is better.
Feedback is fundamental:
Constructive and authentic positive feedback may be difficult to master but it is vital to our success.
Working here:
  • We offer a highly competitive compensation package with meaningful ownership through equity
  • Excellent coverage for medical, vision, and dental
  • 401(k) with generous contribution
  • Life insurance
  • Flexible PTO policy
  • Additional substantial benefits

We are an equal opportunity employer.
We do not discriminate on the basis of race, religion, gender, sexual orientation, age, marital status, veteran status, disability status, national origin, or any characteristic protected under applicable law.

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