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Clinical Trials Protocol Administrator Jobs (NOW HIRING)

Natera

Manager, Clinical Trials

$115K - $144K/yr

Lead study-related activities such as protocol and informed consent preparation, investigator ... for clinical trials management expertise * Monitor and track clinical trial progress and provide ...

Tango Therapeutics

Clinical Trials Manager

Boston, MA · On-site

Act as CTL when assigned, leading cross-functional CTT to operationalize the protocol of a clinical ... for trials without assigned Site Management Lead (SML) What You Bring: * 5+ years of trial ...

Tango Therapeutics

Clinical Trials Manager

Boston, MA · On-site

Act as CTL when assigned, leading cross-functional CTT to operationalize the protocol of a clinical ... for trials without assigned Site Management Lead (SML) What You Bring: * 5+ years of trial ...

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How much do clinical trials protocol administrator jobs pay per hour?

As of Sep 5, 2026, the average hourly pay for clinical trials protocol administrator in the United States is $27.65, according to ZipRecruiter salary data. Most workers in this role earn between $22.84 and $29.81 per hour, depending on experience, location, and employer.

What does a clinical trials protocol administrator do?

A Clinical Trials Protocol Administrator is responsible for coordinating and managing the documentation and logistics related to clinical trial protocols. Their role involves ensuring that all trial procedures comply with regulatory and ethical standards, maintaining accurate records, and facilitating communication between research teams, sponsors, and regulatory bodies. They play a crucial role in starting, monitoring, and closing clinical studies, helping to ensure that protocols are followed and that trials run smoothly.

What are the key skills and qualifications needed to thrive as a clinical trials protocol administrator, and why are they important?

To excel as a Clinical Trials Protocol Administrator, you need a solid background in clinical research, regulatory compliance, and protocol development, often supported by a degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and certifications like Certified Clinical Research Professional (CCRP) are highly beneficial. Strong organizational skills, attention to detail, and effective communication help manage complex documentation and coordinate with multiple stakeholders. These capabilities are crucial for ensuring protocol adherence, data integrity, and the smooth execution of clinical trials.

What are some common challenges faced by clinical trials protocol administrators, and how can they be managed?

Clinical Trials Protocol Administrators often face challenges such as coordinating multiple stakeholders, managing strict regulatory compliance, and maintaining accurate documentation. Balancing the needs of investigators, sponsors, and regulatory bodies requires strong organizational and communication skills. To manage these challenges, administrators typically use project management tools, stay updated on regulations, and establish clear communication channels within the clinical research team. Proactively addressing issues and maintaining detailed records can help ensure trials run smoothly and meet compliance standards.

What is the difference between Clinical Trials Protocol Administrator vs Clinical Research Coordinator?

AspectClinical Trials Protocol AdministratorClinical Research Coordinator
Primary ResponsibilitiesDevelops, reviews, and manages trial protocols, ensuring compliance and accuracyCoordinates daily trial activities, enrolls participants, and collects data
Required CredentialsBachelor's degree in health sciences or related field; certifications like CCRP are commonBachelor's degree in health sciences or related field; often requires clinical research certifications
Work EnvironmentOffice-based, regulatory and administrative settingsClinical sites, hospitals, or research facilities
Industry UsageUsed across pharmaceutical, biotech, and academic research organizationsPrimarily in hospitals, clinics, and research institutions

While both roles support clinical trials, the Clinical Trials Protocol Administrator focuses on protocol development and compliance, whereas the Clinical Research Coordinator handles participant management and daily trial operations.

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Clinical Trials Protocol Administrator jobs near you
Infographic showing various Clinical Trials Protocol Administrator job openings in the United States as of August 2026, with employment types broken down into 3% As Needed, 71% Full Time, 18% Part Time, and 8% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $57,519 per year, or $27.7 per hour.

Manager, Clinical Trials

Natera

Remote

$115K - $144K/yr

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 9 days ago

Natera rating

7.8

Company rating: 7.8 out of 10

Based on 39 frontline employees who took The Breakroom Quiz

55th of 121 rated laboratories

Job description

POSITION SUMMARY:
The Manager, Clinical Trials will be responsible for managing all aspects of clinical trials from start-up through close-out. The Clinical Trial Manager should have experience in managing all aspects of the trials independently, and is expected to provide functional expertise to ensure that study timelines, costs and quality metrics are met and the study is conducted in compliance with the study protocol, SOPs, and applicable regulatory requirements.
PRIMARY RESPONSIBILITIES:
  • Manage the execution and conduct of all aspects of very complex clinical studies to ensure that timelines, cost, and quality metrics are met
  • Responsible for selection of vendors/CROs and provide effective ongoing management to vendors/CROs working on the project to ensure compliance and execution of project deliverables within the approved budget, study timeline, and study protocol. Works closely with investigative site personnel, CROs, and other study vendors
  • Manage study contracting, budget, forecasting, accruals and payment process for all clinical trial vendors including investigational sites
  • Lead study-related activities such as protocol and informed consent preparation, investigator selection, study training material development and delivery, monitoring plans development and execution, CRFs, design and completion, TMF maintenance, protocol amendment and clinical report preparation, as required
  • Collaborate with Clinical Data Management group to ensure correct CRFs content is collected, prepare comprehensive completion guidelines, and design effective data listings and study reports
  • Train CROs, vendors, investigators and study coordinators on implementation of study protocol
  • Hire, train, manage and oversee Clinical trial staff, and serve as a resource for others within the company for clinical trials management expertise
  • Monitor and track clinical trial progress and provide status update to stakeholders
  • Support sample management and prospective sample testing for studies where Natera functions as a central testing facility
  • Partner with other research and development groups to create a culture of mutual respect and focus on delivery of high-quality project results
  • Develop Clinical Department SOPs and participate in audits as needed
  • This role works with PHI on a regular basis both in paper and electronic form and have an access to various technologies to access PHI (paper and electronic) in order to perform the job.
  • Employee must provide records of current training or complete training relating to HIPAA/PHI privacy, Human Subjects Protection, and GCP training.
  • Must maintain a current status on Natera training requirements including General Policies and Procedure Compliance and security training.
  • Employee must pass post offer criminal background check

QUALIFICATIONS:
  • Bachelor's degree in life sciences, or other relevant discipline required, Advanced degree preferred.
  • 8 years of clinical research experience, including at least 4 years of experience in managing clinical trials as a leading role.
  • 4-7 years of experience in supporting clinical trials in a regulated environment .
  • Experience in managing CROs is preferred.

KNOWLEDGE, SKILLS, AND ABILITIES:
  • Knowledge and understanding of Clinical Trial SOPs, FDA Regulations, and ICH-GCPs governing the conduct of clinical trials
  • Demonstrated analytical skills and ability to identify problems and solutions independently
  • Ability to collaborate with the study team, cross functional team members and external collaborators
  • Proficiency in MS Word, Excel and PowerPoint
  • Good organization and planning skills
  • Strong interpersonal skills and communication skills (both written and oral)
  • Strong leadership skills, self-motivated, adaptable to a dynamic and fast paced environment
  • Must have excellent organizational and time management skills.
  • Ability to prioritize and handle multiple tasks and projects in a fast-paced environment

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.
Remote USA
$115,800-$144,700 USD
OUR OPPORTUNITY
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women's health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you'll work hard and grow quickly. Working alongside the elite of the industry, you'll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
If you are based in California, we encourage you to read this important information for California residents.
Link: https://www.natera.com/notice-of-data-collection-california-residents/
Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.
For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page

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