ZipRecruiter

Log In

1

Clinical Trial Risk Based Monitoring Jobs (NOW HIRING)

Fortrea

Clinical Trial Manager

Remote US or Canadian based. Job Overview: The Clinical Trial Manager has ownership in the clinical ... Proactive planning for monitoring activities to ensure data integrity, patient safety and endpoint ...

Impulse Dynamics

Clinical Trial Manager

Marlton, NJ

$95K - $115K/yr

... risk mitigation. * Lead study startup processes, including but not limited to conduct of the ... Monitor the quality of vendor deliverables, address quality issues with the appropriate team member ...

RDI

Clinical Monitoring Standards Lead

Los Angeles, CA · On-site +1

You will also help modernize clinical trial monitoring as the industry moves toward risk-based monitoring, real-time oversight, remote-first execution, and AI-assisted workflows without compromising ...

RDI

Clinical Monitoring Standards Lead

Los Angeles, CA · On-site

You will also help modernize clinical trial monitoring as the industry moves toward risk-based monitoring, real-time oversight, remote-first execution, and AI-assisted workflows without compromising ...

RDI

Clinical Monitoring Standards Lead

Los Angeles, CA · On-site

You will also help modernize clinical trial monitoring as the industry moves toward risk-based monitoring, real-time oversight, remote-first execution, and AI-assisted workflows without compromising ...

ICON

Senior Clinical Research Associate

Washington, DC · On-site +1

$110K - $138K/yr

Solid tumor clinical trial experience is required * Experience utilizing Veeva systems is highly ... Expertise in GxPs and Oncology monitoring techniques (including Risk-Based Monitoring) and ...

Kardigan

Clinical Trial Manager

Princeton, NJ · On-site

Tracks, monitors and reports on study progress * Manages CRO and vendor budgets and invoicing ... Summarizes CRO and vendor performance data and escalates risk to the Clinical Operations Program ...

Prometrika LLC

Clinical Trial Manager

Cambridge, MA · On-site

$140K - $168K/yr

... site monitoring oversight, clinical vendor management, clinical trial risk management, TMF ... management, and regulatory submissions (e.g., CSR, NDA support). * Experience working in cross ...

Ossium Health

Clinical Trial Manager

San Francisco, CA · On-site +1

$145K - $165K/yr

... monitoring. You'll play a key role in launching our PRESERVE II clinical trial, the long-term ... This position is based in our San Francisco office; we maintain a hybrid schedule of Monday ...

next page

Showing results 1-20

All JobsClinical Trial Risk Based Monitoring Jobs

Clinical Trial Risk Based Monitoring information

See salary details

$17

$39

$70

How much do clinical trial risk based monitoring jobs pay per hour?

As of Jul 21, 2026, the average hourly pay for clinical trial risk based monitoring in the United States is $39.99, according to ZipRecruiter salary data. Most workers in this role earn between $32.21 and $43.99 per hour, depending on experience, location, and employer.

How does a Clinical Trial Risk Based Monitoring professional typically collaborate with cross-functional teams during a study?

In a Clinical Trial Risk Based Monitoring role, you will regularly work with clinical research associates, data managers, statisticians, and regulatory teams to identify and address potential risks throughout a study. Collaboration often involves participating in meetings to review data trends, sharing insights about site performance, and helping to develop mitigation strategies. Effective communication is crucial, as you will be responsible for ensuring that all stakeholders are informed of key risks and recommended actions. This collaborative environment helps drive patient safety, data integrity, and overall trial success.

What is the difference between Clinical Trial Risk Based Monitoring vs Clinical Trial Data Manager?

AspectClinical Trial Risk Based MonitoringClinical Trial Data Manager
Primary FocusMonitoring trial sites for risks and complianceManaging and ensuring accuracy of trial data
Required SkillsMonitoring protocols, regulatory knowledge, site managementData management, database systems, quality control
Work EnvironmentClinical sites, monitoring visits, remote oversightData centers, clinical trial databases, office setting
CertificationsGCP, monitoring certificationsCDMP, data management certifications

While both roles are integral to clinical trials, Risk Based Monitoring focuses on overseeing site performance and compliance to mitigate risks, whereas Data Managers concentrate on managing and validating trial data for accuracy and integrity.

What is Clinical Trial Risk Based Monitoring?

Clinical Trial Risk Based Monitoring (RBM) is a strategy used in clinical research to prioritize and focus monitoring activities on the most critical risks to patient safety and data integrity. Instead of monitoring every data point equally, RBM uses data analytics and risk assessment tools to identify which sites, processes, or data require more attention. This approach increases efficiency, reduces costs, and helps ensure that potential issues are detected and addressed promptly. RBM is supported by regulatory agencies and is increasingly adopted in both large and small clinical trials.

What are the key skills and qualifications needed to thrive in Clinical Trial Risk Based Monitoring, and why are they important?

To thrive in Clinical Trial Risk Based Monitoring, you need expertise in clinical research, regulatory compliance, and data analysis, usually supported by a degree in life sciences or related fields. Familiarity with risk assessment tools, EDC (Electronic Data Capture) systems, and GCP (Good Clinical Practice) certification is typically required. Strong attention to detail, critical thinking, and effective communication help professionals proactively identify and address potential risks in trials. These skills are crucial for maintaining data integrity, ensuring patient safety, and optimizing the efficiency and quality of clinical studies.
More about Clinical Trial Risk Based Monitoring jobs
What cities are hiring for Clinical Trial Risk Based Monitoring jobs? Cities with the most Clinical Trial Risk Based Monitoring job openings:
What states have the most Clinical Trial Risk Based Monitoring jobs? States with the most job openings for Clinical Trial Risk Based Monitoring jobs include:
What job categories do people searching Clinical Trial Risk Based Monitoring jobs look for? The top searched job categories for Clinical Trial Risk Based Monitoring jobs are:
Clinical Trial Risk Based Monitoring jobs near you
Infographic showing various Clinical Trial Risk Based Monitoring job openings in the United States as of July 2026, with employment types broken down into 1% As Needed, 75% Full Time, 14% Part Time, and 10% Contract. Highlights an 89% Physical, 2% Hybrid, and 9% Remote job distribution, with an average salary of $83,169 per year, or $40 per hour.

Clinical Trial Manager/Senior Clinical Trial Manager

Oruka Therapeutics

Waltham, MA • On-site

Full-time

Re-posted 11 days ago

Job description

About Us:
Oruka Therapeutics (Nasdaq: ORKA) is developing novel biologics designed to set a new standard for the treatment of chronic skin diseases. Oruka's mission is to offer patients suffering from chronic skin diseases like plaque psoriasis the greatest possible freedom from their condition by achieving high rates of complete disease clearance with dosing as infrequently as once or twice per year. Oruka is advancing a proprietary portfolio of potentially best-in-class antibodies that were engineered by Paragon Therapeutics and target the core mechanisms underlying plaque psoriasis and other dermatologic and inflammatory diseases. For more information, visit www.orukatx.com
As we build our core team, we're seeking top talent in different functional areas who are not just looking for a job, but an opportunity to be part of something bigger. Someone who is passionate about making a difference and eager to contribute to establishing an engaged, inclusive, and positive company culture.
Job Title: Clinical Trial Manager/Senior Clinical Trial Manager
Location: Hybrid 3 days/week if located near office in Waltham, MA or Menlo Park, CA will be required. Remote may be considered.
About Us:
Oruka Therapeutics (Nasdaq: ORKA) is developing novel biologics designed to set a new standard for the treatment of chronic skin diseases. Oruka's mission is to offer patients suffering from chronic skin diseases like plaque psoriasis the greatest possible freedom from their condition by achieving high rates of complete disease clearance with dosing as infrequently as once or twice per year. Oruka is advancing a proprietary portfolio of potentially best-in-class antibodies that were engineered by Paragon Therapeutics and target the core mechanisms underlying plaque psoriasis and other dermatologic and inflammatory diseases. For more information, visit www.orukatx.com
As we build our core team, we're seeking top talent in different functional areas who are not just looking for a job, but an opportunity to be part of something bigger. Someone who is passionate about making a difference and eager to contribute to establishing an engaged, inclusive, and positive company culture.
Role Overview:
Will ensure trial compliance, regulatory alignment, and operational efficiency while collaborating with cross-functional teams to advance Oruka's clinical pipeline. Independently manage the clinical trial by effectively planning and executing the study to ensure quality of deliverables within the specified budget and timeframe. May serve as the clinical functional lead and lead clinical trial initiatives for Oruka's cutting-edge dermatology treatments.
Key Responsibilities:
  • Clinical Trial Management:
    • Lead and manage multiple clinical trials from initiation through to completion, ensuring adherence to study timelines and budgets.
    • Collaborate with investigators, vendors, and cross-functional teams to ensure study execution and operational excellence.
    • Oversee the preparation and review of trial-related documentation, including protocols, informed consent forms (ICFs), case report forms (CRFs), and study reports.
    • In partnership with Program Management, develop and drive cross functional study timelines related to trial setup and execution.
  • Team Leadership:
    • Drive the cross functional internal study team ensuring appropriate alignment, risk management and coordination across all participating functions.
    • Successfully interface with Data Management, Biostatistics and Clinical Development to ensure seamless monitoring and data cleaning initiatives to meet study deliverables and timelines
    • Foster a collaborative team environment focused on operational efficiency and continuous improvement.
  • Regulatory and Compliance Oversight:
    • Ensure that clinical trials are conducted in compliance with all applicable regulations, including FDA, EMA, and ICH-GCP guidelines.
    • Support the preparation and submission of clinical trial applications, including INDs, NDAs, and other regulatory documents with functional leads.
    • Manage interactions with Regulatory Affairs and external vendors to ensure timely submissions and approvals.
  • Budget and Resource Management:
    • Develop and manage clinical trial budgets, ensuring efficient use of resources and timely financial reporting.
    • Monitor and control trial costs to ensure alignment with project forecasts and company objectives.
    • Negotiate contracts and budgets with clinical vendors and investigators.
  • Vendor and Site Management:
    • Oversee the selection and management of clinical vendors (CROs, laboratories, etc.) and ensure they meet performance expectations.
    • Develop strong relationships with clinical sites and external partners to ensure aggressive site startup, high-quality data collection and trial conduct.
    • Perform risk assessment and management, addressing issues proactively to mitigate operational issues.

Qualifications:
  • Bachelor's or Master's degree in life sciences or a related field.
  • 5-7+ years of experience in clinical operations, with a focus on managing complex clinical trials.
  • Expertise in GCP and regulatory requirements.
  • Strong leadership and team management skills.

Compensation:
  • An appropriate financial package will be developed for the successful candidate to include a competitive base salary and equity, with a performance-related bonus opportunity.
  • The anticipated salary range for Manager level is $146,000 - $161,000 and Sr. Manager level is $161,000 - $187,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc. Oruka is a multi-state employer and this salary range may not reflect positions that work in other states.

Job Location:
  • Hybrid 3 days/week if located near office in Waltham, MA or Menlo Park, CA will be required. Remote may be considered.

We're looking forward to hearing how you can contribute to our team and mission. Join us in shaping the future of our company and making a real impact every day.
Salary Range for the Role
$146,000-$187,000 USD
What We Offer:
  • A chance to be part of a vibrant startup culture where your work can directly impact bringing new medicines to patients.
  • Competitive salary and benefits package.
  • A supportive and inclusive team environment where everyone is encouraged to bring their authentic selves to work.
  • Opportunities for professional growth and development.

Apply