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Clinical Sme Jobs (NOW HIRING)

Oran, Inc.

Clinical SME I

Herndon, VA · On-site +1

Position Title Clinical SME I Overview We are seeking a Clinical Subject Matter Expert (SME) with extensive experience in clinical trial operations, FDA regulatory processes, and protocol development.

Oran Inc

Clinical SME I

Herndon, VA · Remote

Position Title Clinical SME I Overview We are seeking a Clinical Subject Matter Expert (SME) with extensive experience in clinical trial operations, FDA regulatory processes, and protocol development.

InfoMC

Clinical Business Analyst

Conshohocken, PA · On-site +1

About the role The Clinical Business Analyst serves as a Subject Matter Expert (SME) for InfoMC's utilization management (UM) and care management (CM) applications, acting as a trusted advisor to ...

PointClickCare

Clinical Affairs Director

$81K - $111K/yr

Serve as a clinical SME, bridging the gap between clinical best practices and product innovation. * Collaborate with product and engineering teams to enhance medication management, decision-support ...

Nemean Solutions, LLC

The Certified Registered Nurse Anesthetist (CRNA) - Clinical SME/Instructor provides doctoral-level nurse anesthesia education and instruction for the U.S. Army Graduate Program in Anesthesia Nursing ...

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How much do clinical sme jobs pay per hour?

As of Jul 14, 2026, the average hourly pay for clinical sme in the United States is $34.62, according to ZipRecruiter salary data. Most workers in this role earn between $16.59 and $32.93 per hour, depending on experience, location, and employer.

What is a SME job position?

A Subject Matter Expert (SME) in a job context is a professional with deep knowledge and expertise in a specific area or field. SMEs often provide guidance, training, and support to teams, and may be involved in developing standards, procedures, or solutions related to their specialty.

What holistic job makes the most money?

Among holistic health professions, medical doctors specializing in integrative or functional medicine tend to earn the highest salaries, often exceeding six figures annually. These roles typically require advanced degrees, certifications, and extensive clinical experience. Other high-paying holistic careers include licensed acupuncturists and naturopathic doctors, but their earnings are generally lower than those of medical doctors.

What is a Clinical SME job?

A Clinical Subject Matter Expert (SME) is a professional with specialized knowledge in clinical processes, healthcare regulations, or medical best practices. They provide expertise to support clinical operations, product development, or compliance initiatives. Clinical SMEs often work with cross-functional teams, offering insights on medical protocols, regulatory requirements, and industry standards to improve healthcare solutions and patient outcomes.

What does a typical workday look like for a Clinical SME, and how do they interact with project teams?

A typical day for a Clinical SME involves reviewing clinical protocols, providing expert recommendations, and ensuring that practices and documentation meet regulatory compliance. You can expect to collaborate closely with project managers, data analysts, and regulatory teams to guide decision-making and resolve complex clinical questions. Many Clinical SMEs serve as a critical bridge between clinical staff and technical or administrative teams, participating in meetings, training sessions, and quality assurance reviews. This role frequently involves both independent research and dynamic teamwork, making strong interpersonal skills essential for success.

What is a clinical SME job description?

A clinical SME (Subject Matter Expert) is a professional with in-depth knowledge of clinical processes, regulations, and medical terminology who provides expertise to develop, review, and validate clinical content, protocols, or systems. They often collaborate with cross-functional teams, ensure compliance with industry standards, and may hold certifications such as RAC or CCRP. Strong communication skills and familiarity with electronic health records or clinical trial management systems are also important.

What are the key skills and qualifications needed to thrive in the Clinical Sme position, and why are they important?

To thrive as a Clinical SME (Subject Matter Expert), you need in-depth clinical expertise, often supported by an advanced healthcare degree and significant hands-on experience in a relevant discipline. Familiarity with clinical data management systems, regulatory guidelines (such as HIPAA or GCP), and proficiency in tools like EHRs or clinical trial platforms are common requirements. Strong analytical thinking, effective communication, and the ability to collaborate cross-functionally distinguish top performers in this role. These skills ensure the SME can provide accurate guidance, drive project success, and uphold clinical quality standards.

What does clinical sme mean?

A Clinical SME (Subject Matter Expert) is a professional with specialized knowledge in clinical or medical fields, often providing expertise in clinical trials, healthcare processes, or medical documentation. They typically support product development, regulatory submissions, or training, and may hold relevant certifications or advanced degrees in healthcare or life sciences.
More about Clinical Sme jobs
What are the most commonly searched types of Clinical Sme jobs? The most popular types of Clinical Sme jobs are:
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Clinical Sme jobs near you
Infographic showing various Clinical Sme job openings in the United States as of July 2026, with employment types broken down into 100% Full Time. Highlights an 33% In-person, and 67% Remote job distribution, with an average salary of $72,002 per year, or $34.6 per hour.
Clinical SME I

Clinical SME I

Oran, Inc.

Herndon, VA • On-site, Remote

Full-time

Re-posted 22 days ago

Job description

Position Title
Clinical SME I
Overview
We are seeking a Clinical Subject Matter Expert (SME) with extensive experience in clinical trial operations, FDA regulatory processes, and protocol development. The ideal candidate will provide scientific and regulatory expertise supporting clinical research and healthcare initiatives.
Key Responsibilities
  • Review and analyze clinical trial protocols and regulatory documentation.
  • Provide guidance on FDA regulatory requirements and ICH guidelines.
  • Support protocol development, study design, and safety review processes.
  • Evaluate inclusion/exclusion criteria, endpoints, and risk-benefit assessments.
  • Collaborate with clinical, regulatory, and technical teams.
  • Assist in pharmacovigilance and informed consent review activities.
  • Provide subject matter expertise for healthcare and clinical research initiatives.
  • Ensure compliance with applicable federal and clinical research regulations.

Required Qualifications
  • Advanced degree preferred:
    • MD
    • PharmD
    • RN
    • MPH
    • MS in Clinical Research
    • Related clinical/scientific discipline
  • Minimum 10 years of relevant clinical research or regulatory experience.
  • Deep understanding of:
    • Clinical trial protocols
    • FDA regulatory review processes
    • Drug development lifecycle
    • Safety review
    • Protocol design

Required Skills
  • Clinical protocol review
  • ICH guidelines
  • FDA regulatory processes
  • Pharmacovigilance
  • Study design
  • Endpoint analysis
  • Risk-benefit evaluation
  • Informed consent review

Preferred Qualifications
  • RAC (Regulatory Affairs Certification)
  • Active clinical licensure preferred.

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