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Rapid Strategy

FHIR SME Consultant

Windsor Mill, MD · On-site

$160K/yr

We are seeking a FHIR Subject Matter Expert (SME) Consultant to advise on healthcare ... solutions meet clinical, operational, and regulatory needs. * Guide clients in adopting ...

OpenLoop Health, Inc

Clinical Informaticist

Serve as the clinical subject matter expert (SME) for product and project teams, providing guidance on clinical workflows, clinical knowledge, and best practices for clinical data * Design, build ...

Jorie AI

EPIC SME

Oak Brook, IL · On-site

$120K/yr

... SME) serves as the organization's primary resource for Epic-related processes, workflows, and ... This individual partners closely with clinical, operational, and technical stakeholders to ensure ...

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How much do clinical sme jobs pay per hour?

As of Aug 16, 2026, the average hourly pay for clinical sme in the United States is $34.62, according to ZipRecruiter salary data. Most workers in this role earn between $16.59 and $32.93 per hour, depending on experience, location, and employer.

What is a clinical SME?

A Clinical Subject Matter Expert (SME) is a professional with specialized knowledge in clinical processes, healthcare regulations, or medical best practices. They provide expertise to support clinical operations, product development, or compliance initiatives. Clinical SMEs often work with cross-functional teams, offering insights on medical protocols, regulatory requirements, and industry standards to improve healthcare solutions and patient outcomes.

What does a clinical SME do?

A typical day for a Clinical SME involves reviewing clinical protocols, providing expert recommendations, and ensuring that practices and documentation meet regulatory compliance. You can expect to collaborate closely with project managers, data analysts, and regulatory teams to guide decision-making and resolve complex clinical questions. Many Clinical SMEs serve as a critical bridge between clinical staff and technical or administrative teams, participating in meetings, training sessions, and quality assurance reviews. This role frequently involves both independent research and dynamic teamwork, making strong interpersonal skills essential for success.

What skills and qualifications are needed to thrive as a clinical SME?

To thrive as a Clinical SME (Subject Matter Expert), you need in-depth clinical expertise, often supported by an advanced healthcare degree and significant hands-on experience in a relevant discipline. Familiarity with clinical data management systems, regulatory guidelines (such as HIPAA or GCP), and proficiency in tools like EHRs or clinical trial platforms are common requirements. Strong analytical thinking, effective communication, and the ability to collaborate cross-functionally distinguish top performers in this role. These skills ensure the SME can provide accurate guidance, drive project success, and uphold clinical quality standards.

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Clinical Sme jobs near you
Infographic showing various Clinical Sme job openings in the United States as of August 2026, with employment types broken down into 3% As Needed, 72% Full Time, 17% Part Time, and 8% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $72,002 per year, or $34.6 per hour.

Artificial Intelligence SME

Tunnell Government Services

Washington, DC

Full-time

Re-posted 20 days ago

Job description

Tunnell Government Services, Inc., is comprised of the industry's leading scientists, medical and technical experts, and human capital and organizational development professionals. We approach all projects as a team and are committed to helping our clients transform and quickly achieve strategic goals. If you are interested in joining an employee-owned company that develops and implements innovative, integrated and differentiated solutions, please click on the links below to find the job that is right for you and contact us.

Artificial Intelligence SME
A Subject Matter Expert (SME) in artificial intelligence with a focus on healthcare and biomedical research is needed to provide contracted support to the Biomedical Advanced Research and Development Authority (BARDA), within the U.S. Department of Health and Human Services (HHS) in Washington, DC. The mission of BARDA is to develop and procure medical countermeasures (MCM) that address the public health and medical consequences of chemical, biological, radiological, and nuclear (CBRN) accidents, incidents and attacks, pandemic influenza, and emerging infectious diseases. Specifically, BARDA supports the advanced development and procurement of drugs, vaccines and other products that are considered priorities for national health security. For more information on BARDA please visit their website at: http://www.phe.gov/about/BARDA/Pages/default.aspx
Specifically, this individual will provide strategic, technical, and scientific expertise on the application of artificial intelligence (AI), machine learning (ML), and advanced data analytics to BARDA's mission of developing and procuring medical countermeasures (MCMs) for public health emergencies. The AI SME will advise leadership, program managers, and technical teams on the integration of AI technologies across BARDA's programs, ensuring the agency remains at the forefront of innovation in biodefense, pandemic preparedness, and health security.

Major Duties & Responsibilities:

  • Advise BARDA leadership on emerging trends, opportunities, and risks in AI and related technologies for vaccines and/or therapeutics development.
  • Provide subject matter expertise to BARDA divisions in evaluating AI-enabled technologies, tools, and proposals.
  • Assess AI approaches used in diagnostics, therapeutics, and vaccines including review of algorithms and algorithm performance
  • Guide the design, implementation, and validation of AI applications to ensure scientific rigor, transparency, and compliance with federal policies.
  • Contribute to the formulation of policies, standards, and ethical frameworks governing AI use within BARDA.
  • Perform expert analysis and provide recommendations for applications of machine learning/artificial intelligence tools and capabilities to field of biotech research and development (e.g. digital health, drug discovery and design, clinical validation).
  • Evaluating diverse data sets for use with AI products/tools, such as EHR, claims, laboratory/clinical data, physiological data, genomic data, viral variant data, and/or social determinants of health data.
  • Advising on improvements to data collection and curation, developing standards, and developing data use and sharing agreements to enable AI applications
  • Advising R&D partnerships developing artificial intelligence products/tools to improve model function, design clinical validation studies, and implement production deployment and maintenance processes.


Requirements:

  • Advanced degree (Ph.D. or M.S) in Computer Science, Data Science, Engineering, Bioinformatics, or a related field
  • 15+ years of experience in vaccines and/or therapeutics development
  • Minimum of 8-10 years of experience applying AI/ML in healthcare, biomedical research, or health security contexts
  • Demonstrated expertise in algorithm development, data modeling, and AI governance
  • Demonstrated ability to communicate complex AI concepts to diverse stakeholders
  • Demonstrated experience serving as technical expert and leader in machine learning/artificial intelligence, data analytics, and algorithm development using medical and/or biological data.
  • Demonstrated understanding of software development principles and cloud-based platforms and services relevant to AI development.
  • Expertise in understanding artificial intelligence model function, clinical validation, production deployment, and ongoing maintenance

Must be a US Citizen or Full Green Card holder.

Tunnell strives to hire and retain the most qualified talent. We believe that having employees with different backgrounds and capabilities contributes to the success of our business. To attract qualified applicants, Tunnell posts to a wide variety of job sites. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

Please be advised that certain client contracts may outline specific requirements for onsite work. Tunnell employees and/or contractors are expected to comply with all client requirements, including any safety and health protocols.