ZipRecruiter

Log In

1

Clinical Research Operations Jobs (NOW HIRING)

Actalent

Research Nurse Manager

Detroit, MI · Hybrid

The Clinical Research Nurse Manager oversees all aspects of people management, supports day-to-day operations, contributes to strategic planning for research initiatives, and may occasionally provide ...

TriHealth

Manager Clinical Research

Montgomery, OH · On-site

In this role, you'll oversee research operations from - program development and regulatory compliance to financial and strategic planning - guiding protocol evaluation, clinical trial execution, and ...

TriHealth

Manager Clinical Research

Montgomery, OH · On-site

In this role, you'll oversee research operations from - program development and regulatory compliance to financial and strategic planning - guiding protocol evaluation, clinical trial execution, and ...

Southwest Women's Oncology

Be Seen First

Clinical Research Director

Albuquerque, NM · On-site

Clinical Research Director Southwest Women's Oncology | Albuquerque, New Mexico Why This Role ... Trial Operations * Lead the full lifecycle of clinical trials--feasibility, start-up, recruitment ...

City of Hope

Manager, Clinical Research

Duarte, CA

We are seeking an experienced and inspiring Clinical Research Nurse Manager to lead clinical research operations, elevate quality patient care, and support a high-performing team in a dynamic ...

next page

Showing results 1-20

All JobsClinical Research Operations Jobs

Clinical Research Operations information

See salary details

$49K

$107.3K

$189K

How much do clinical research operations jobs pay per year?

As of Jun 16, 2026, the average yearly pay for clinical research operations in the United States is $107,336.00, according to ZipRecruiter salary data. Most workers in this role earn between $81,000.00 and $122,500.00 per year, depending on experience, location, and employer.

Is CRA an entry level job?

A Clinical Research Associate (CRA) is typically an intermediate or experienced role that requires prior knowledge of clinical trial processes, good clinical practice (GCP), and often some related experience. Entry-level positions in clinical research may be labeled as Clinical Trial Assistants or Coordinators, with CRAs usually needing a bachelor's degree and relevant training or certifications before advancing to this role.

What is the difference between Clinical Research Operations vs Clinical Research Coordinators?

AspectClinical Research OperationsClinical Research Coordinators
CredentialsTypically requires a degree in life sciences, certifications like CCRP or RACOften requires a bachelor's degree in health sciences or related field, with certifications like CCRP beneficial
Work EnvironmentOversees multiple studies, manages teams, and collaborates with sponsors and regulatory bodiesWorks directly with study participants, manages data collection, and ensures protocol adherence
Employer & Industry UsageUsed in pharmaceutical companies, CROs, and research institutionsCommonly employed in hospitals, clinics, and research sites

Clinical Research Operations professionals focus on managing entire research programs, budgets, and teams, while Clinical Research Coordinators handle day-to-day study activities and participant interactions. Both roles are essential but differ in scope and responsibilities within the clinical research field.

What are some common challenges faced in clinical research operations and how can they be addressed?

Professionals in clinical research operations often encounter challenges such as managing complex regulatory requirements, coordinating across multidisciplinary teams, and ensuring adherence to strict timelines. Successfully addressing these challenges typically involves strong project management skills, effective communication with stakeholders, and staying updated on regulatory changes. Leveraging technology for data management and fostering a collaborative work environment can also help streamline processes and improve trial outcomes.

Which is better, CRC or CRA?

Clinical Research Coordinators (CRCs) and Clinical Research Associates (CRAs) have different roles in clinical trials; CRCs typically manage study conduct at sites, while CRAs monitor trial progress across multiple sites. Both roles require strong organizational skills and knowledge of Good Clinical Practice (GCP), but CRAs often need more experience in monitoring and may travel frequently. The choice depends on your career interests, as CRCs focus on site management and patient interaction, whereas CRAs focus on oversight and compliance.

What is clinical research operations?

Clinical research operations refer to the planning, execution, and management of clinical trials and studies that test new medical treatments, drugs, or devices. This field ensures that studies are conducted ethically, efficiently, and in compliance with regulatory guidelines. Professionals in clinical research operations coordinate activities such as patient recruitment, data collection, regulatory submissions, and quality control. Their work is essential for advancing medical knowledge and ensuring the safety and effectiveness of new healthcare interventions.

How much does a CRC make?

A Clinical Research Coordinator (CRC) in Houston typically earns between $50,000 and $70,000 annually, depending on experience, certifications, and the complexity of trials managed. Salaries can vary based on the employer, clinical setting, and additional skills such as data management or regulatory knowledge.

Is it hard to get a CRA job?

Securing a Clinical Research Associate (CRA) position can be competitive, often requiring relevant experience, a degree in life sciences or related fields, and knowledge of Good Clinical Practice (GCP) guidelines. Entry-level roles may be available for those with strong academic backgrounds or internships, but advancing typically involves gaining experience and certifications such as the CCRP or RAC. The job market varies based on industry demand and geographic location.

What are the key skills and qualifications needed to thrive in Clinical Research Operations, and why are they important?

To thrive in Clinical Research Operations, you need a strong understanding of clinical trial protocols, regulatory guidelines (such as ICH-GCP), and project management, typically supported by a degree in life sciences or a related field. Familiarity with electronic data capture (EDC) systems, clinical trial management systems (CTMS), and certifications like ACRP or SOCRA are often required. Exceptional organizational skills, attention to detail, and effective communication are crucial soft skills for coordinating teams and ensuring compliance. These competencies are vital for maintaining data integrity, meeting regulatory standards, and successfully managing complex clinical studies.
More about Clinical Research Operations jobs
What cities are hiring for Clinical Research Operations jobs? Cities with the most Clinical Research Operations job openings:
What are the most commonly searched types of Clinical Research Operations jobs? The most popular types of Clinical Research Operations jobs are:
What states have the most Clinical Research Operations jobs? States with the most job openings for Clinical Research Operations jobs include:
What job categories do people searching Clinical Research Operations jobs look for? The top searched job categories for Clinical Research Operations jobs are:
Clinical Research Operations jobs near you
Infographic showing various Clinical Research Operations job openings in the United States as of June 2026, with employment types broken down into 4% As Needed, 87% Full Time, 7% Part Time, 1% Contract, and 1% Nights. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $107,336 per year, or $51.6 per hour.
Clinical Research Director

Clinical Research Director

OneOncology

Charlotte, NC

Full-time

Posted 10 days ago

OneOncology rating

7.7

Company rating: 7.7 out of 10

Based on 16 frontline employees who took The Breakroom Quiz

Job description

Carolina Oncology Specialists has been caring for patients in Catawba County since 1983, offering patients high quality, personalized healthcare close to their own home so patients and caregivers don't have to travel far for excellent care. Our patients experience the convenience of in-clinic chemotherapy treatments, as well as the treatment and management of blood disorders.

Why Join Us? We are looking for talented and highly-motivated individuals who demonstrate a natural desire to support the meaningful work of community oncologists and the patients we serve.

Job Description:

Position Name:Clinical Research Director
Reports to:Operations Manager
FLSA Status:Exempt
Department:Clinical Research
Location:Carolina Oncology Specialist Pineville Location

JOB SUMMARY:

The Clinical Research Directoris responsible forthe strategic leadership, operational oversight, and continued growth of the clinical research program at Carolina Oncology Specialist. This roleensuresall oncology clinical trials are conducted in compliance with ICH-GCP guidelines, regulatory requirements, and organizational policies while advancing the site's research capabilities and patient access to innovative therapies.

The Director provides leadership to research staff, oversees study portfolios, manages sponsor and CRO relationships, and drives high-quality, efficient study execution. The ideal candidate is an experienced oncology research professional with strong leadership, regulatoryexpertise, and operational management skills.

ESSENTIAL FUNCTIONS:

Provides strategic direction and oversight for all clinical research operations, including study start-up, enrollment, conduct, and close-out.

Leads and manages the clinical research team, including Clinical Research Coordinators, regulatory staff, and research support personnel.

Develops and implements departmental goals, KPIs, and growth strategies to expand oncology clinical trial offerings.

Oversees study feasibility assessments, site selection, and study activation processes.

Ensurescompliance with ICH-GCP, FDA regulations, IRB requirements, and institutional policies across all studies.

Maintains accountability for the quality and integrity of clinical trial data and patient safety.

Oversees regulatory operations, including IRB submissions, amendments, continuing reviews, and audit readiness.

Ensuressuccessful execution of sponsor monitoring visits, audits, and regulatory inspections.

Establishes andmaintainsstrong relationships with sponsors, CROs, investigators, and research partners.

Monitors study enrollment, timelines, and financial performance, ensuring targets are met.

Collaborates with finance and leadership on study budgets, contract negotiations, and resource allocation.

Oversees adverse event reporting, protocol deviations, and compliance-related issues.

Develops and implements SOPs, policies, and process improvements for research operations.

Supports physician investigators in research engagement, protocol development, and study execution.

Provides staff training, mentorship, and performance management to ensure high-functioning teams.

Ensures effective communication across departments, including infusion, lab, pharmacy, and administrative teams.

Identifiesopportunities to expand research services, partnerships, and trial access for patients.

Representsthe organization in external research initiatives, sponsor meetings, and industry collaborations.

Promotes a culture of quality, compliance, and continuous improvement within the research department.

KNOWLEDGE, SKILLS & ABILITIES:

Extensive knowledge of ICH-GCP, FDA regulations, and clinical trial compliance requirements.

Strong understanding of oncology clinical trials, including treatment modalities and safety reporting (CTCAE, RECIST).

Proven leadership and team management skills with the ability to develop and motivate staff.

Expertise inclinical trial operations, study lifecycle management, and regulatory processes.

Ability to analyze data, manage budgets, and make strategic decisions.

Excellent organizational, problem-solving, and project management skills.

Strong communicationand interpersonal skills with the ability to collaborate with internal and external stakeholders.

Ability to manage multiple priorities in a fast-paced clinical environment.

High levelof attention to detail and commitment to patient safety and data integrity.

EDUCATION & EXPERIENCE:

Bachelor's degree in life sciences, healthcare, nursing, or related fieldrequired.

Master's degree (MBA, MPH, or similar) preferred.

Minimum of 5-7 years of clinical research experience, with at least 3 years in a leadership or management role.

Extensive experience inoncologyclinical researchstronglypreferred.

Experience managing multi-study portfolios and research teams.

Certification (CCRC, CCRP, or equivalent)preferred.

Experience with sponsor/CRO partnerships, budgets, and contract negotiationsstronglypreferred.

PHYSICAL REQUIREMENTS:

Must be able to sit, stand, and walk for extended periods.

Must be able tolift upto 25 pounds.

May require occasional travel between clinic locations, conferences, or sponsor meetings.

What OneOncology employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom

Apply