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Clinical Research Operations Jobs (NOW HIRING)

The Program Lead will oversee all start-up operations across five clinical research centers, ensuring fast and efficient activation. The PL is responsible for the development, coordination, and ...

Provides strategic, operational, regulatory, financial, and program leadership for the Heart & Vascular clinical research portfolio. Directs program-level planning, workforce development, and ...

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Clinical Research Operations information

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$49K

$107.3K

$189K

How much do clinical research operations jobs pay per year?

As of Jul 7, 2026, the average yearly pay for clinical research operations in the United States is $107,336.00, according to ZipRecruiter salary data. Most workers in this role earn between $81,000.00 and $122,500.00 per year, depending on experience, location, and employer.

Is CRA an entry level job?

A Clinical Research Associate (CRA) is typically not an entry-level position; it usually requires prior experience in clinical research, monitoring, or related healthcare fields. Entry-level roles in clinical research often include Clinical Trial Assistants or Coordinators, with CRAs generally needing knowledge of Good Clinical Practice (GCP) and relevant certifications such as CCRP or RAC.

What is the difference between Clinical Research Operations vs Clinical Research Coordinators?

AspectClinical Research OperationsClinical Research Coordinators
CredentialsTypically requires a degree in life sciences, certifications like CCRP or RACOften requires a bachelor's degree in health sciences or related field, with certifications like CCRP beneficial
Work EnvironmentOversees multiple studies, manages teams, and collaborates with sponsors and regulatory bodiesWorks directly with study participants, manages data collection, and ensures protocol adherence
Employer & Industry UsageUsed in pharmaceutical companies, CROs, and research institutionsCommonly employed in hospitals, clinics, and research sites

Clinical Research Operations professionals focus on managing entire research programs, budgets, and teams, while Clinical Research Coordinators handle day-to-day study activities and participant interactions. Both roles are essential but differ in scope and responsibilities within the clinical research field.

What are some common challenges faced in clinical research operations and how can they be addressed?

Professionals in clinical research operations often encounter challenges such as managing complex regulatory requirements, coordinating across multidisciplinary teams, and ensuring adherence to strict timelines. Successfully addressing these challenges typically involves strong project management skills, effective communication with stakeholders, and staying updated on regulatory changes. Leveraging technology for data management and fostering a collaborative work environment can also help streamline processes and improve trial outcomes.

What is clinical research operations?

Clinical research operations refer to the planning, execution, and management of clinical trials and studies that test new medical treatments, drugs, or devices. This field ensures that studies are conducted ethically, efficiently, and in compliance with regulatory guidelines. Professionals in clinical research operations coordinate activities such as patient recruitment, data collection, regulatory submissions, and quality control. Their work is essential for advancing medical knowledge and ensuring the safety and effectiveness of new healthcare interventions.

What is the highest paying job in clinical research?

In clinical research operations, senior roles such as Clinical Research Director or Vice President of Clinical Operations typically have the highest salaries, often exceeding six figures. These positions require extensive experience, leadership skills, and often advanced certifications like RAC or CCRP, and they oversee multiple projects or departments within pharmaceutical or biotech companies.

Is CRC an entry level position?

A Clinical Research Coordinator (CRC) position is often considered entry level, suitable for individuals with a bachelor's degree in health or science fields. Prior experience or certifications like Good Clinical Practice (GCP) can enhance job prospects, but many organizations hire CRCs with minimal experience and provide on-the-job training.

Is CRA better than CRC?

A Clinical Research Associate (CRA) and a Clinical Research Coordinator (CRC) are different roles in clinical trials. CRAs typically oversee multiple sites, monitor study progress, and ensure compliance, often requiring travel and certification such as ACRP or SOCRA. CRCs manage day-to-day trial activities at a single site, handle patient interactions, and coordinate study procedures, often working closely with the site team and requiring strong organizational skills.

What are the key skills and qualifications needed to thrive in Clinical Research Operations, and why are they important?

To thrive in Clinical Research Operations, you need a strong understanding of clinical trial protocols, regulatory guidelines (such as ICH-GCP), and project management, typically supported by a degree in life sciences or a related field. Familiarity with electronic data capture (EDC) systems, clinical trial management systems (CTMS), and certifications like ACRP or SOCRA are often required. Exceptional organizational skills, attention to detail, and effective communication are crucial soft skills for coordinating teams and ensuring compliance. These competencies are vital for maintaining data integrity, meeting regulatory standards, and successfully managing complex clinical studies.
More about Clinical Research Operations jobs
What cities are hiring for Clinical Research Operations jobs? Cities with the most Clinical Research Operations job openings:
What are the most commonly searched types of Clinical Research Operations jobs? The most popular types of Clinical Research Operations jobs are:
What states have the most Clinical Research Operations jobs? States with the most job openings for Clinical Research Operations jobs include:

Clinical Research Site Manager

Chronic Pain Research Institute

Charlotte, NC • On-site

Other

Posted 3 days ago

New


Job description

🔬 Clinical Research Manager

Location: Raleigh, NC

Employment Type: Full-Time

Posted by: chronic Pain Research Institute on behalf of Client


🌟 About the Opportunity

Our client is a highly respected neurosurgery and interventional pain management group that is launching an innovative clinical research center. This is a unique opportunity to join at the ground level and play a pivotal role in building and leading a growing research program focused on advancing therapies in neurology, pain management, and medical devices.


We are seeking a Clinical Research Manager to oversee and develop all aspects of the research operations. The ideal candidate is experienced, organized, and passionate about clinical research, with the ability to lead teams and establish efficient processes from the ground up.


🧩 Key Responsibilities
  • Lead the startup, development, and day-to-day management of clinical research operations
  • Oversee clinical trials, including device and drug studies, ensuring compliance with protocols, GCP, and regulatory requirements
  • Manage and mentor clinical research staff (coordinators, assistants, regulatory personnel)
  • Develop and implement SOPs, workflows, and quality systems
  • Act as primary liaison with sponsors, CROs, IRBs, and regulatory bodies
  • Ensure accurate data collection, documentation, and reporting
  • Oversee budgeting, study feasibility, and financial management of trials
  • Prepare for and manage audits and monitoring visits
  • Support site growth strategy, including study selection and startup activities


✅ Qualifications
  • Bachelor’s degree required (life sciences, nursing, or related field preferred)
  • 5+ years of clinical research experience, with at least 2 years in a leadership or management role
  • Strong knowledge of FDA regulations, ICH-GCP, and clinical trial processes
  • Experience in neurosurgery, pain management, CNS, or medical device trials strongly preferred
  • Proven ability to build and manage research programs or teams
  • Excellent organizational, communication, and leadership skills

Certifications such as CCRC, CCRP, or CPI are a plus.


💡 Why This Role?
  • Ground-floor leadership role in a brand-new research center
  • Work alongside a highly reputable physician group
  • Opportunity to shape and grow a cutting-edge clinical research program
  • Competitive compensation and benefits
  • Meaningful impact on advancing treatments for patients in need


📩 How to Apply

Apply directly via LinkedIn or send your resume to: shill@chronicpainresearchinstitute.com