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Clinical Applications Manager Jobs in California

$210.20 - $289.05/hr

Title: Executive Director Epic Clinical Applications Location: Fountain Valley, CA Department ... Hire and manage staff that support the diverse application portfolio while maintain a primary focus ...

$16.25 - $21.50/hr

What You Can Expect The Clinical Applications Intern is responsible for providing support to the Biostatistics & Clinical Data Management (BCDM) department in the development and maintenance of ...

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Clinical Applications Manager information

See California salary details

$53.3K

$112.1K

$151K

How much do clinical applications manager jobs pay per year?

As of Aug 17, 2026, the average yearly pay for clinical applications manager in California is $112,073.00, according to ZipRecruiter salary data. Most workers in this role earn between $99,700.00 and $124,800.00 per year, depending on experience, location, and employer.

What is a clinical applications manager?

A Clinical Applications Manager oversees the implementation, management, and optimization of clinical software applications within healthcare organizations. They work closely with clinical staff, IT teams, and vendors to ensure that clinical information systems such as electronic health records (EHR) operate efficiently and meet the needs of healthcare providers. Their responsibilities often include training staff, troubleshooting issues, and ensuring compliance with healthcare regulations. This role requires a combination of technical knowledge, leadership skills, and an understanding of clinical workflows.

What are the key skills and qualifications needed to thrive as a clinical applications manager, and why are they important?

To thrive as a Clinical Applications Manager, you need in-depth knowledge of clinical workflows, healthcare IT systems, and a relevant degree such as in health informatics or information technology. Familiarity with electronic health records (EHR), clinical decision support systems, and certifications like Epic or Cerner are typically required. Strong leadership, problem-solving abilities, and effective communication are vital soft skills for managing teams and interfacing with both technical and clinical stakeholders. These skills ensure the effective implementation, optimization, and support of clinical applications, directly impacting patient care and operational efficiency.

What are some common challenges faced by clinical applications managers when implementing new healthcare software systems?

Clinical Applications Managers often encounter challenges such as ensuring seamless integration with existing hospital systems, managing user adoption among clinical staff, and meeting regulatory compliance requirements. They must coordinate closely with IT, clinical teams, and vendors to address technical issues and workflow disruptions. Successful managers proactively communicate changes, provide thorough training, and gather feedback to optimize system performance and user satisfaction.

What is the difference between Clinical Applications Manager vs Clinical Systems Specialist?

AspectClinical Applications ManagerClinical Systems Specialist
CredentialsTypically requires a bachelor's degree in healthcare, IT, or related field; certifications like Epic or Cerner are commonOften holds similar degrees and certifications, focusing on specific clinical systems expertise
Work EnvironmentManages clinical software implementation, training, and support within healthcare facilitiesProvides technical support, troubleshooting, and system optimization for clinical software
Employer & Industry UsageUsed by hospitals, clinics, and healthcare organizations for system managementEmployed in similar settings, often working alongside Clinical Applications Managers

The Clinical Applications Manager and Clinical Systems Specialist roles overlap in healthcare IT, with the manager focusing on overseeing system deployment and staff training, while the specialist provides technical support and system troubleshooting. Both roles require clinical IT knowledge and certifications, but the manager has broader responsibilities in project management and team coordination.

What are the most commonly searched types of Clinical Applications jobs in California?

The most popular types of Clinical Applications jobs in California are:

What cities in California are hiring for Clinical Applications Manager jobs?

Cities in California with the most Clinical Applications Manager job openings:

Infographic showing various Clinical Applications Manager job openings in California as of August 2026, with employment types broken down into 77% Full Time, 20% Part Time, 2% Temporary, and 1% Contract. Highlights an 84% Physical, 3% Hybrid, and 13% Remote job distribution, with an average salary of $112,073 per year, or $53.9 per hour.

Clinical Applications Specialist

Spyglass Pharma

Aliso Viejo, CA โ€ข On-site, Remote

Full-time

Medical, Dental, Vision, PTO

Re-posted 3 days ago


Job description

About SpyGlass Pharma:


At SpyGlass Pharma, we are focused on improving and preserving the vision of patients suffering from chronic eye conditions, while minimizing the impact on their daily lives. We aim to achieve this by developing cutting-edge long-term drug delivery products to address common causes of blindness and getting these products to the patients that need them.

We have built a team of driven professionals with diverse expertise in ophthalmic products and drug delivery. Our accomplished scientists and engineers work alongside a seasoned leadership team with extensive experience in ophthalmology and a history of commercial success. Our unifying mantra, "We create for patients" doesn't just live on our walls but drives our decision making as we build the company, creating the products, processes and culture that make it happen.

This team has delivered a solid foundation of development and clinical data, enabling over $370 million in funding to date with several top-tier venture partners. We are building confidence in the performance of our lead product currently enrolling patients in Phase 3 clinical trials.


Summary:


SpyGlass Pharma is seeking a Clinical Application Specialist with a strong grasp of cataract surgery and a solid understanding of surgical protocol and OR flow. This role focuses on supporting surgeons and site staff during the assembly and delivery of SpyGlass's sustained-release drug delivery technology, which is integrated into the cataract procedure. This role also includes assisting with patient identification, and recruitment in collaboration with site teams.
The ideal candidate brings experience in the operating room, the ability to guide surgical teams through precise device preparation and delivery, and clear, confident communication skills. This is a field-based role requiring regular travel to clinical trial sites and close collaboration with the Clinical Applications Manager and cross-functional teams.


Please note:This is a U.S. based, remote position that requires regular travel to clinical trial sites across the country (up to 70%). Applicants must be currently authorized to work in the United States and comfortable with a travel-based schedule.

Essential Duties and Responsibilities:

  • Provide hands-on procedural support during implant cases, offering real-time coaching and troubleshooting to ensure successful use of SpyGlass's sustained-release drug delivery technology.
  • Train and coach surgical staff-including surgeons, scrub techs, and circulating nurses-on proper assembly and delivery of the device.
  • Ensure site teams are confident in integrating SpyGlass's technology into existing surgical workflows.
  • Train clinic staff in explaining SpyGlass's technology and its benefits to patients.
  • Collaborate with the Clinical Applications Manager and other team members to report procedural feedback and contribute to training improvements.
  • Maintain compliance with FDA regulations, GCP guidelines, and SpyGlass Pharma's internal SOPs.
  • Represent SpyGlass in a professional manner during site visits, meetings, and industry events as needed.


Qualifications Required for Position:

  • Bachelor's degree in life sciences, nursing, healthcare, or a related field preferred.
  • 5+ years of experience in clinical, surgical support, or ophthalmic medical device roles, ideally with cataract surgery.
  • Comfortable providing support and guidance in operating room settings.
  • Demonstrated ability to instruct clinical and surgical staff on device setup and procedural workflow.
  • Strong observational skills and attention to detail during surgical procedures.
  • Clear and professional verbal and written communication skills.
  • Familiarity with clinical research environments and regulatory compliance (e.g., FDA, GCP).
  • Ability to travel up to 70% to support trial sites across the U.S.
  • Proficiency in Microsoft Office and clinical documentation systems.


Why SpyGlass Pharma?

  • We are offering a range of $90,000 - $130,000, based on experience and qualifications, along with an Annual Bonus opportunity.
  • Share in our success with stock options, giving you a stake in the company's future.
  • Comprehensive health, dental, and vision insurance plans to keep you and your family healthy and happy, with a variety of plan and coverage options.
  • Generous paid time off, including holidays, vacation days, and personal leave.


SpyGlass Pharma is an Equal Opportunity Employer and participates in E-Verify. SpyGlass Pharma takes pride in maintaining a diverse environment and our policies are not to discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity, marital or veteran status, disability, or any other legally protected status.

SpyGlass Pharma is also committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an email to JOBS@SPYGLASSPHARMA.COM and let us know the nature of your request and your contact information.