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Merck Group

Chromatography Expert

San Diego, CA · On-site

$85K - $187K/yr

Chromatography Expert Must sit on west coast Your role: We are seeking a Chromatography Expert with an engineering background to support Protein A chromatography adoption by our clients. This is a ...

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How much do chromatography jobs pay per hour?

As of Jun 6, 2026, the average hourly pay for chromatography in the United States is $31.54, according to ZipRecruiter salary data. Most workers in this role earn between $23.80 and $35.82 per hour, depending on experience, location, and employer.

What are the typical daily responsibilities for someone working in chromatography?

Professionals in chromatography roles routinely prepare and analyze samples using various chromatography methods like HPLC or GC, interpret results, and document findings according to industry standards. They are responsible for calibrating and maintaining analytical instruments, troubleshooting equipment issues, and adhering to strict quality control protocols. Collaboration with other scientists, quality assurance teams, and production staff is common to support research, product development, or regulatory compliance. Depending on the workplace, you may also be involved in method development or validation, making the role both dynamic and integral to scientific operations.

What is a Chromatography job?

A chromatography job involves analyzing chemical compounds using chromatography techniques to separate, identify, and quantify substances in a mixture. Professionals in this field work in laboratories, often in pharmaceutical, environmental, food safety, or research settings. They operate chromatography instruments like HPLC, GC, or ion chromatography systems, interpret results, and ensure quality control. Strong analytical skills and knowledge of laboratory protocols are essential for success.

What are the key skills and qualifications needed to thrive in the Chromatography position, and why are they important?

To thrive in a chromatography role, you need a background in chemistry or biochemistry with hands-on experience in analytical laboratory techniques. Proficiency with chromatographic instruments such as HPLC, GC, and related data analysis software—often backed by certifications like CLP (Certified Lab Professional)—is highly valued. Strong attention to detail, problem-solving skills, and effective communication enhance performance and teamwork in this role. Mastering these skills ensures accurate results, reliable quality control, and effective collaboration in laboratory and research settings.

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Chromatography jobs near you
Infographic showing various Chromatography job openings in the United States as of May 2026, with employment types broken down into 93% Full Time, 2% Part Time, 1% Temporary, 3% Contract, and 1% Nights. Highlights an 92% Physical, 1% Hybrid, and 7% Remote job distribution, with an average salary of $65,597 per year, or $31.5 per hour.

Chromatography Expert

Merck Group

San Diego, CA • On-site

$85K - $187K/yr

Full-time

Medical, Retirement, PTO

Posted 22 days ago

Job description

Work Location: San Diego, California
Shift:
Department: LS-PS-PC Chrom & JSR Integration
Recruiter: Paul Therrien
This information is for internals only. Please do not share outside of the organization.
Chromatography Expert
Must sit on west coast
Your role: We are seeking a Chromatography Expert with an engineering background to support Protein A chromatography adoption by our clients. This is a customer facing role as part of a global Protein A focused team, where you will work in close partnership with MilliporeSigma's Account Managers to cater to client's technical needs which may include direction on PD trials and optimization, pilot and process-scale runs, column packing guidance, and troubleshooting issues that arise during operations.
You will serve as a key technical contact supporting biopharmaceutical clients with critical chromatography purification projects. Your responsibilities are to:
• Provide expertise to support clients with process development, scale-up, and implementation of JSR chromatographic resin used for antibody purification, via remote consultation or on-site support.
• Design and execute experimental protocols to understand process sensitivity and troubleshoot operational issues with minimal supervision. Critically analyze data and model process behavior to characterize process performance or troubleshoot root cause. Clearly communicate recommendations to GMP biopharmaceutical customers.
• Assist and train clients with resin column packing.
• Serve as key interface with Sales, R&D, and Marketing teams to communicate Voice of the Customer and Market Trends.
• Travel requirement up to 30%
Minimum Qualifications:
• Bachelor's of Science in Chemical Engineering or Biotechnology with 10+ year's related experience OR Master's of Science in Chemical Engineering with 8+ year's related experience OR PhD in Chemical Engineering or Biotechnology with 5-7+ years' experience.
• 5-7+ years practical experience with downstream biologics purification in a manufacturing or process development environment, including a knowledge of scale-up, process transfer, and cGMP manufacturing.
Preferred Qualifications:
• In depth experience with chromatography operations at pilot or manufacturing scale, including column packing, process validation, and troubleshooting operational issues.
• An understanding of bioprocess economics, as well as strong knowledge of scale-up and scale-down sizing principles.
• A sound knowledge of process engineering fundamentals, especially fluid dynamics.
• Ability to communicate technical concepts to colleagues and clients using excellent written and verbal communication skills.
• Dependable, self-motivated, and able to thrive in an autonomous working environment.
Pay Range: $85,300- $187,700
The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.
The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.

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