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High Performance Liquid Chromatography Jobs (NOW HIRING)

Reversed-phase high-performance liquid chromatography (RP-HPLC) * Sample preparation and handling * Plate-based analytical methods * Experience with operation, maintenance, and troubleshooting Liquid ...

Scientist

Cambridge, MA · On-site

$151K/yr

Provide training, troubleshooting, and oversight of high performance liquid chromatography (HPLC) analyses; Analyses include size-exclusion, cation and anion exchange, affinity, and reversed phase ...

Scientist

Cambridge, MA · On-site +1

$151K/yr

Provide training, troubleshooting, and oversight of high performance liquid chromatography (HPLC) analyses; Analyses include size-exclusion, cation and anion exchange, affinity, and reversed phase ...

Primary disciplines include by not limited to Gel Permeation Chromatography (GPC), High Performance Liquid Chromatography (HPLC), Liquid Chromatography-Mass Spectrometry (LCMS) * Secondary ...

Primary disciplines include by not limited to Gel Permeation Chromatography (GPC), High Performance Liquid Chromatography (HPLC), Liquid Chromatography-Mass Spectrometry (LCMS) * Secondary ...

... High Performance Liquid Chromatographs HPLC Ultra-Performance Liquid Chromatographs UPLC _ . Leading supplier of chromatography and spectrometry instrumentation seeks a Field Service Engineer to ...

... High Performance Liquid Chromatographs HPLC Ultra-Performance Liquid Chromatographs UPLC _ . Leading supplier of chromatography and spectrometry instrumentation seeks a Field Service Engineer to ...

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High Performance Liquid Chromatography information

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$40K

$99.5K

$153.5K

How much do high performance liquid chromatography jobs pay per year?

As of Jun 7, 2026, the average yearly pay for high performance liquid chromatography in the United States is $99,528.00, according to ZipRecruiter salary data. Most workers in this role earn between $65,500.00 and $126,000.00 per year, depending on experience, location, and employer.

What are some typical daily responsibilities for someone working with High Performance Liquid Chromatography (HPLC)?

In an HPLC role, your daily responsibilities often include preparing samples, calibrating and maintaining HPLC instruments, running analytical tests, and interpreting chromatographic data. You may also be responsible for troubleshooting equipment issues, documenting results in lab notebooks or electronic systems, and ensuring all work complies with safety and quality standards. Collaboration with other analysts, scientists, and quality assurance teams is common, particularly when optimizing analytical methods or supporting research and development projects. This dynamic and detail-oriented role plays an essential part in quality control, product development, and research within pharmaceutical, environmental, and chemical industries.

What are the key skills and qualifications needed to thrive in the High Performance Liquid Chromatography position, and why are they important?

To thrive in a High Performance Liquid Chromatography (HPLC) role, you need a solid background in chemistry, analytical techniques, and laboratory procedures, usually supported by a degree in chemistry, biochemistry, or a related field. Familiarity with HPLC instrumentation, chromatography software, and relevant quality and safety certifications such as GLP or GMP is highly beneficial. Attention to detail, strong problem-solving skills, and effective communication are valuable soft skills in this position. These skills and qualities ensure accurate analysis, regulatory compliance, and productive collaboration within laboratory settings.

What is a High Performance Liquid Chromatography job?

A High Performance Liquid Chromatography (HPLC) job typically involves analyzing and testing substances using HPLC techniques to separate, identify, and quantify compounds in a mixture. Professionals in this field, such as laboratory analysts or chemists, operate and maintain HPLC instruments, interpret results, and ensure compliance with industry standards. These roles are common in pharmaceutical, environmental, food, and chemical industries. Strong analytical skills, attention to detail, and knowledge of chromatography principles are essential for success in HPLC jobs.

What cities are hiring for High Performance Liquid Chromatography jobs? Cities with the most High Performance Liquid Chromatography job openings:
What are the most commonly searched types of High Performance Liquid Chromatography jobs? The most popular types of High Performance Liquid Chromatography jobs are:
What states have the most High Performance Liquid Chromatography jobs? States with the most job openings for High Performance Liquid Chromatography jobs include:
What job categories do people searching High Performance Liquid Chromatography jobs look for? The top searched job categories for High Performance Liquid Chromatography jobs are:
Infographic showing various High Performance Liquid Chromatography job openings in the United States as of May 2026, with employment types broken down into 14% As Needed, 29% Full Time, 2% Part Time, 5% Temporary, 44% Contract, and 6% Nights. Highlights an 92% Physical, 1% Hybrid, and 7% Remote job distribution, with an average salary of $99,528 per year, or $47.9 per hour.
Scientist III - Liquid Chromatography-Mass Spectrometry (LC-MS) and Analytical Support - FSP

Scientist III - Liquid Chromatography-Mass Spectrometry (LC-MS) and Analytical Support - FSP

Parexel

Full-time

Retirement, PTO

Posted 3 days ago


Job description

When our values align, there's no limit to what we can achieve.
At Parexel, we all share the same goal - to improve the world's health. From clinical trials to regulatory, consulting, and market access, every clinical development solution we provide is underpinned by something special - a deep conviction in what we do.

Each of us, no matter what we do at Parexel, contributes to the development of a therapy that ultimately will benefit a patient. We take our work personally, we do it with empathy and we're committed to making a difference.

We are looking to fill a Scientist III - Liquid Chromatography-Mass Spectrometry (LC-MS) and Analytical Support position working as a full-time employee of Parexel FSP on long-term assignment onsite at one of our clients located in West Point, PA. This position offers full benefits, sick time, 401K, paid holidays, and paid time off. This role does not offer sponsorship.

Qualifications

  • Scientist 3 - B.S. in Chemistry or related field with 3-5 years of experience; M.S. with 1-2 years

Responsibilities

Open Access and Instrument Support:

  • Responds to end-user repair calls for Liquid Chromatography-Mass Spectrometry (LC-MS) and troubleshoots/repairs simple issues such as leaks or clogs.

  • Checks instrument performance and suitability as needed.

  • Submits and coordinates repair tickets for more complex issues.

  • Maintains accurate documentation and records.

Vaccines Analytical Support:

  • Sample preparations for routine analysis, including total protein, enzymatic digests, and electrophoresis.

  • Liquid Chromatography (LC) and Liquid Chromatography-Mass Spectrometry (LC-MS) analysis of vaccine samples as needed.

  • Biophysical sample testing as needed, including particle size and thermal stability analysis

Provides General Lab support

  • General lab support, which may include; organization of pipette calibration, ordering lab supplies, general lab maintenance, COSMIC organization, shipping

Required Skills and Experience

Experienced in analytical characterization techniques such as:

  • Liquid Chromatography-Mass Spectrometry (LC-MS) experience with Waters, Sciex, or Agilent LC-MS instrumentation and software

  • Reversed-phase high-performance liquid chromatography (RP-HPLC)

  • Sample preparation and handling

  • Plate-based analytical methods

  • Experience with operation, maintenance, and troubleshooting Liquid Chromatography-Mass Spectrometry (LC-MS)

  • Highly organized, and capable of multi-tasking to manage system related schedules, documents, and maintenance tasks for multiple instruments

  • Strong communication and collaboration skills in a fast paced, team environment.

  • Ability to multi - task and deliver on multiple priorities simultaneously.

About Parexel

Parexel FSP includes the CMC Operations group. We provide pharmaceutical and biopharmaceutical companies with qualified and talented technical professionals to support the development and delivery of new therapies.

For results-driven and caring individuals who want to make a meaningful difference in the world, Parexel is trusted by life sciences companies to meet their long-term staffing needs for scientists and engineers and related professionals in discovery and development of novel therapies, keeping patients at the center of everything we do, and where an inclusive community helps you be your best, transforming any career into a life-changing achievement.

Come join us!

#LI-DK1

EEO Disclaimer
Parexel is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to legally protected status, which in the US includes race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.


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About PAREXEL

Sourced by ZipRecruiter

Bring your Data Management expertise to Parexel's Strategic Partnerships. Although we work globally, each partnership we form is deeply personal. We are as dedicated to every aspect of our client's product development as they are - and work closely with client teams in true partnership to understand both challenges and opportunities. At Parexel we are focused on meeting customer and patient needs through collaborative partnership so that we get treatments into the hands of patients who need them most.

Industry

Pharmaceutical and medicine manufacturing

Company size

10,000+ Employees

Headquarters location

Waltham, MA, US

Year founded

1983