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Biotech Software Jobs in California (NOW HIRING)

BigHat Biosciences

Senior Software Engineer

San Mateo, CA

$139K - $183K/yr

Candidates with prior experience in biotech, life sciences, or scientific software may be considered with fewer total years of software engineering experience. *At BigHat we believe in titles that ...

Chestnut

Software Engineer

San Francisco, CA · On-site

They are seeking a Software Engineer to build automated mortgage brokering and potentially take on ... finance, biotech, etc.). • Desire to found your own company some day. We will do everything we ...

Chestnut

Software Engineer

San Francisco, CA · On-site

The Software Engineer will contribute to building automated mortgage brokering and may later take ... finance, biotech, etc.). • Desire to found your own company some day. We will do everything we ...

PSC Biotech

Validation Engineer I

San Francisco, CA · Remote

$20 - $23/hr

PSC Biotech provides the life sciences with essential services to ensure that health care products ... Knowledge of the Software Development Cycle is preferred. * Excellent technical computer skills.

Danaher

Software Engineer Internships

Fresno, CA · On-site

About Software Engineering Roles at Danaher Are you passionate about building real-world ... biotechnology. Our global teams work every day to solve the world's most complex challenges by ...

Danaher

Software Engineer Internships

Merced, CA · On-site

About Software Engineering Roles at Danaher Are you passionate about building real-world ... biotechnology. Our global teams work every day to solve the world's most complex challenges by ...

Danaher

About Software Engineering Roles at Danaher Are you passionate about building real-world ... biotechnology. Our global teams work every day to solve the world's most complex challenges by ...

Danaher

About Software Engineering Roles at Danaher Are you passionate about building real-world ... biotechnology. Our global teams work every day to solve the world's most complex challenges by ...

Danaher

About Software Engineering Roles at Danaher Are you passionate about building real-world ... biotechnology. Our global teams work every day to solve the world's most complex challenges by ...

Danaher

About Software Engineering Roles at Danaher Are you passionate about building real-world ... biotechnology. Our global teams work every day to solve the world's most complex challenges by ...

Danaher

Software Engineer Internships

Arcata, CA · On-site

About Software Engineering Roles at Danaher Are you passionate about building real-world ... biotechnology. Our global teams work every day to solve the world's most complex challenges by ...

Danaher

About Software Engineering Roles at Danaher Are you passionate about building real-world ... biotechnology. Our global teams work every day to solve the world's most complex challenges by ...

Danaher

Software Engineer Internships

San Jose, CA · On-site

About Software Engineering Roles at Danaher Are you passionate about building real-world ... biotechnology. Our global teams work every day to solve the world's most complex challenges by ...

Danaher

Software Engineer Internships

Stockton, CA · On-site

About Software Engineering Roles at Danaher Are you passionate about building real-world ... biotechnology. Our global teams work every day to solve the world's most complex challenges by ...

Danaher

About Software Engineering Roles at Danaher Are you passionate about building real-world ... biotechnology. Our global teams work every day to solve the world's most complex challenges by ...

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Showing results 21-40

All JobsBiotech Software JobsBiotech Software Jobs in California

Biotech Software information

See California salary details

$47.4K

$110.4K

$163.8K

How much do biotech software jobs pay per year?

As of Aug 16, 2026, the average yearly pay for biotech software in California is $110,380.00, according to ZipRecruiter salary data. Most workers in this role earn between $88,800.00 and $128,300.00 per year, depending on experience, location, and employer.

What is biotech software?

Biotech software refers to computer programs and platforms designed specifically to support research, development, and operations in the biotechnology industry. These tools can help with tasks such as DNA sequencing, data analysis, laboratory management, and simulation of biological processes. Biotech software enables scientists and organizations to manage large datasets, automate experiments, and accelerate discoveries in areas like genetics, pharmaceuticals, and medical diagnostics. The software is crucial for improving accuracy, efficiency, and compliance in biotech workflows.

How does a biotech software professional typically collaborate with scientists and laboratory staff?

Biotech Software professionals frequently work alongside scientists, researchers, and laboratory staff to develop, customize, and maintain software tools that support experimental workflows and data analysis. Regular communication is essential to ensure that software solutions meet the specific needs of biological research, from managing large datasets to automating laboratory processes. This collaboration often involves requirements gathering, user training, troubleshooting, and iterative improvements based on user feedback. Building strong interdisciplinary relationships is key to delivering effective and user-friendly software in the biotech environment.

What are the key skills and qualifications needed to thrive as a biotech software engineer, and why are they important?

To thrive as a Biotech Software Engineer, you need a strong background in computer science, bioinformatics, or related fields, often supported by a relevant degree and experience in software development for biological or healthcare applications. Familiarity with programming languages such as Python or R, databases, cloud platforms, and tools like BLAST or Genome Analysis Toolkit (GATK) is typically required. Excellent problem-solving ability, teamwork, and clear communication help professionals integrate complex biological data and collaborate with interdisciplinary teams. These skills are crucial for developing robust software solutions that enable scientific discovery and advance biotechnology research.

What is the difference between Biotech Software vs Laboratory Technician?

AspectBiotech SoftwareLaboratory Technician
Required CredentialsDegree in biotech, computer science, or related field; knowledge of biotech software toolsAssociate's or Bachelor's in laboratory sciences; technical certifications often preferred
Work EnvironmentOffice or lab setting focused on software development, data analysis, and biotech applicationsHands-on lab environment performing experiments and sample analysis
Employer & Industry UsageBiotech companies, software firms, research institutionsResearch labs, hospitals, biotech manufacturing facilities

Biotech Software professionals focus on developing, implementing, and maintaining software solutions for biotech research and development, while Laboratory Technicians perform hands-on lab work to conduct experiments and analyze samples. Both roles are essential in the biotech industry but differ in skills, environment, and daily tasks.

What are popular job titles related to Biotech Software jobs in California?

For Biotech Software jobs in California, the most frequently searched job titles are:

What job categories do people searching Biotech Software jobs in California look for?

The top searched job categories for Biotech Software jobs in California are:

What cities in California are hiring for Biotech Software jobs?

Cities in California with the most Biotech Software job openings:

Biotech Software jobs near you
Infographic showing various Biotech Software job openings in California as of August 2026, with employment types broken down into 1% Internship, 85% Full Time, 9% Part Time, 2% Temporary, and 3% Contract. Highlights an 87% Physical, 4% Hybrid, and 9% Remote job distribution, with an average salary of $110,380 per year, or $53.1 per hour.

Senior Software Engineer

BigHat Biosciences

San Mateo, CA

$139K - $183K/yr

Full-time

Medical, Dental, Vision, Retirement

Re-posted 23 days ago

Job description

Description
The role: BigHat Biosciences is looking for a Senior Software Engineer to join our engineering team. This role is for experienced engineers ready to own a significant area of our platform as a subject-matter expert, lead epics end-to-end, and shape the architecture and engineering practices that support the design, build, and testing of therapeutic antibodies at scale. You will work closely with engineers, product partners, and laboratory scientists to build and evolve the internal software systems at the center of our science.
This role is leveled as Senior Software Engineer I. At this level, you operate as a subject-matter expert in your area, working with a high degree of independence and regularly leading epics. Candidates with prior experience in biotech, life sciences, or scientific software may be considered with fewer total years of software engineering experience.
*At BigHat we believe in titles that commensurate with skill set, relative organizational impact, and value contribution; more experienced candidates are encouraged to apply, with the understanding that responsibilities and title would adjust as appropriate.

Key Responsibilities
  • Lead projects end-to-end, from PRD through implementation, testing, release, and validation against the customer success metric.
  • Own one or more major areas of BigHat's internally developed, cloud-based platform as a subject-matter expert, and serve as a cross-team and cross-org resource for those areas.
  • Take on net-new, 0-to-1 work from specification, designing interactions between features and the infrastructure that supports them, and producing novel solutions where existing patterns fall short.
  • Collaborate with, and increasingly manage, the relationship with scientists and product owners to translate real-world lab workflows into reliable software, and to iterate on success metrics.
  • Operate and run engineering processes: PRD reviews, stand-ups, PR approvals, and other team ceremonies.
  • Own the quality and outcomes of your work and your epics, including debugging, test failures, and production issues, anticipating next steps and owning the trajectory of major features.
  • Drive technical depth across the codebase, infrastructure, and systems, and actively improve the design and architectural principles the team works within.
  • Design and build high-quality software across front-end (UI/UX) and back-end systems, with system-level expertise in the databases, AWS services, runtimes, and processes that underpin them.
  • Lead and review technical designs and PRDs; contribute architectural direction and surface risks and tradeoffs early.
  • Write, maintain, and raise the bar on automated testing to ensure correctness, reliability, and maintainability.
  • Run code reviews as a routine approver, providing thoughtful, high-leverage feedback that develops other engineers.
  • Diagnose and resolve complex issues across production and development environments, including across system and environment boundaries.
  • Improve internal engineering practices, documentation, tooling, and architecture; help set and transmit appropriate urgency in partnership with engineering leaders.

Skills Knowledge and Expertise
  • You have a track record of owning features and epics end to end in a production software environment.
  • You are an SME in at least one significant technical area and are reaching to master new ones.
  • You work highly independently and initiate the collaborations needed to deliver work that bridges many parts of the codebase.
  • You balance development, architecture, and process effectively, and help the team prioritize where effort yields the most impact.
  • You communicate clearly about progress, risks, and tradeoffs, and your own outcomes, following issues through to resolution and validating that you've met the customer's needs.
  • You are motivated by building software that supports real users doing complex, high-stakes scientific work.
  • You adapt well as priorities and focus areas shift, and you collaborate effectively with engineers inside and outside your direct team.
  • 7+ years of professional software engineering experience building and owning production systems, including demonstrated end-to-end ownership of features or epics, OR
  • 5+ years of professional software engineering experience with prior experience in biotech, life sciences, laboratory environments, or scientific software, where domain knowledge meaningfully accelerates impact.
Depth in several of the following, with the ability to make and improve system- and architecture-level decisions:
  • TypeScript, React, Material-UI, Vega
  • Python 3, SQLAlchemy
  • RESTful API design
  • AWS (CDK, Lambda, Step Functions, ECS/Batch, Fargate, API Gateway, Athena)
  • Relational databases (e.g., PostgreSQL), including schema and query design
  • Pandas
  • PyTorch or other ML frameworks (nice to have, not required)

Total Rewards
The salary estimated for this position is $198,00 - $215,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.
What BigHat Offers:
  • Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
  • Dental, and vision coverage through Guardian
  • Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more
  • 401(k) with company match 
  • DTO, two weeks of company-wide shutdown, and 12 company holidays
  • Paid parental leave