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Bioinformatics Engineer Jobs in California (NOW HIRING)

LatchBio

AI Biologist - Proteomics

San Francisco, CA · On-site +1

$120K - $180K/yr

Bioinformatics Engineer - Proteomics As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building ...

LatchBio

AI Biologist - Proteomics

San Francisco, CA · On-site

$120K - $180K/yr

Bioinformatics Engineer - Proteomics As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building ...

LatchBio

AI Biologist - Biosurveillance

San Francisco, CA · On-site +1

$120K - $180K/yr

Bioinformatics Engineer - Biosurveillance As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building ...

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All JobsBioinformatics Engineer JobsBioinformatics Engineer Jobs in California

Bioinformatics Engineer information

See California salary details

$42.4K

$129.3K

$235.4K

How much do bioinformatics engineer jobs pay per year?

As of Sep 15, 2026, the average yearly pay for bioinformatics engineer in California is $129,337.00, according to ZipRecruiter salary data. Most workers in this role earn between $94,700.00 and $154,900.00 per year, depending on experience, location, and employer.

What is a bioinformatics engineer?

A Bioinformatics Engineer is a professional who combines expertise in computer science, statistics, and biology to develop software tools and algorithms for analyzing biological data. They often work with large datasets such as genomic sequences, protein structures, and clinical information to help scientists make sense of complex biological systems. Their work is essential in fields like genomics, personalized medicine, and drug discovery, where managing and interpreting vast amounts of data is crucial. Bioinformatics Engineers may also collaborate with researchers to design experiments and interpret results, bridging the gap between biology and technology.

What are the key skills and qualifications needed to thrive as a bioinformatics engineer?

To thrive as a Bioinformatics Engineer, you need a strong background in biology, computer science, and statistics, often supported by a degree in bioinformatics or a related field. Experience with programming languages such as Python or R, familiarity with databases, and knowledge of tools like BLAST, Bioconductor, or next-generation sequencing (NGS) analysis platforms are typically required. Strong problem-solving, analytical thinking, and effective communication skills help you collaborate with interdisciplinary teams and convey complex findings. These skills and qualifications are essential for efficiently analyzing biological data, developing robust computational tools, and advancing research in genomics and life sciences.

What are some common challenges faced by bioinformatics engineers when integrating new data sources into existing pipelines?

Bioinformatics Engineers often encounter challenges such as data format inconsistencies, varying quality of datasets, and the need to ensure compatibility with existing analysis pipelines. Integrating new data sources may require custom scripts or tools for parsing and preprocessing, as well as thorough validation to maintain reproducibility and reliability of results. Collaboration with wet-lab scientists and software engineers is essential to clarify data requirements and streamline the integration process.

What is the difference between Bioinformatics Engineer vs Bioinformatics Analyst?

AspectBioinformatics EngineerBioinformatics Analyst
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related fields; programming skillsBachelor's or Master's in Bioinformatics, Biology, or related fields; data analysis skills
Work EnvironmentResearch labs, biotech companies, pharmaceutical firmsResearch institutions, healthcare organizations, biotech companies
Employer & Industry UsageDevelops tools, pipelines, and software for biological data analysisInterprets data, performs statistical analysis, and reports findings

While both roles require a background in bioinformatics and involve working with biological data, Bioinformatics Engineers focus on developing software and tools, whereas Bioinformatics Analysts primarily analyze and interpret data to support research and decision-making.

What does a bioinformatics engineer do?

A bioinformatics engineer develops and applies computational tools and algorithms to analyze biological data, such as genetic sequences and molecular structures. They often work with programming languages like Python or R, utilize databases, and collaborate with biologists to interpret data for research or medical purposes.
More about Bioinformatics Engineer jobs

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For Bioinformatics Engineer jobs in California, the most frequently searched job titles are:

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Bioinformatics Engineer jobs near you
Infographic showing various Bioinformatics Engineer job openings in California as of August 2026, with employment types broken down into 87% Full Time, 8% Part Time, and 5% Contract. Highlights an 85% Physical, 5% Hybrid, and 10% Remote job distribution, with an average salary of $129,337 per year, or $62.2 per hour.

Bioinformatics Production Engineer

South San Francisco, CA • On-site

Natera
Biotechnology Research and Development • 1 - 5K employees
Learn more about Nateraexternal

$114K - $143K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 20 days ago

Natera rating

7.8

Company rating: 7.8 out of 10

Based on 39 frontline employees who took The Breakroom Quiz

Job description

POSITION SUMMARY:
The Bioinformatics Production Analyst performs basic data analysis to provide bioinformatics support for Horizon Carrier Screening and future platform sequencing tests, while actively participating in production pipeline improvements. In this role, the analyst plays a pivotal part in ensuring Natera provides high-quality carrier screening and sequencing products.
PRIMARY RESPONSIBILITIES:
  • Data Analysis & Processing: Analyze high-throughput DNA sequencing data and perform basic data analysis to support product development, validation studies, and incoming experiment analysis requests.
  • Pipeline Improvement & Support: Help move data through the analysis pipeline while proactively identifying and implementing improvements to production workflows.
  • Troubleshooting: Investigate and resolve technical issues related to data quality, analysis pipelines, and system integration.
  • Cross-Functional Collaboration: Communicate effectively and work collaboratively with cross-functional teams, including biology, software engineering, lab operations, and medical/legal affairs.
  • Documentation: Produce high-quality written documentation, including formal study plans and technical reports.
  • Compliance & PHI Safety: Regularly handle Protected Health Information (PHI) in both paper and electronic formats, ensuring strict adherence to data privacy technologies and protocols.
  • Training & Certification: Complete required HIPAA/PHI privacy, security, and General Policies and Procedures Compliance training within the first 30 days of hire, and maintain current status on all ongoing company training requirements.

QUALIFICATIONS:
Minimum Qualifications:
  • Bachelor's degree in Biomedical Engineering, Computer Science, Bioinformatics, or a related equivalent field.
  • 2+ years of relevant professional experience.

Preferred Qualifications:
  • Master's degree in a relevant scientific or technical discipline.
  • Previous professional experience within the biotechnology, diagnostics, or pharmaceutical industry.

KNOWLEDGE, SKILLS, AND ABILITIES:
  • Knowledge of biological concepts related to molecular biology, cell biology (specifically related to DNA/RNA), and genetics.
  • Experience and knowledge of how Sequencing Assays work.
  • Experience using Python for data analysis and plotting is preferred.
  • Experience using Linux command-line tools and relational databases (SQL) preferred, knowledge of data visualization tools/platforms a plus (plotly).
  • Knowledge of genomics, relevant NGS analyses (mapping, variant calling, etc.), and NGS file types is required. e.g. Know how to run pipelines and knowledge of pipeline platforms/languages (WDL, Nextflow).
  • Ability to produce high quality written documentation for varying audiences, e.g. validation reports
  • Familiarity with Large Language Models (LLMs), such as Claude Code, and how to leverage them to streamline workflows and tasks.
  • Ability to work independently while managing multiple objectives and timelines.
  • Desire to work in a fast-paced environment with potential for high impact in a small team.
  • Team player, self-motivated, and detail-oriented.

Compensation & Total Rewards
This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.
This position is also eligible for additional compensation and benefits through Natera's robust Total Rewards program, including:
  • Long-term equity awards
  • Comprehensive health benefits (medical, dental, vision)
  • 401(k) with company match
  • Generous paid time off and company holidays
  • Additional wellness and work-life benefits

Compensation Range
$114,400-$143,000 USD
OUR OPPORTUNITY
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women's health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you'll work hard and grow quickly. Working alongside the elite of the industry, you'll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
If you are based in California, we encourage you to read this important information for California residents.
Link: https://www.natera.com/notice-of-data-collection-california-residents/
Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.
For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page

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