Binder Jobs (NOW HIRING)

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Job Description

We are seeking a highly capable and experimentally driven Scientist, Protein Engineering & Binder Discovery to join Kite Research. This role will be focused on the planning, execution, and screening of new binder discovery and optimization campaigns.

This is a labbased, handson role for a Scientist who enjoys translating discovery hypotheses into welldesigned experimental campaigns and carrying them through execution. The Scientist will take ownership of binder campaign design and screening strategy while remaining deeply engaged at the bench, generating highquality experimental data that directly informs program decisions.

Key Responsibilities

Binder Campaign Design & Experimental Planning (Primary Focus)

• Design and plan new binder discovery and optimization campaigns, including selection strategies, screening formats, and experimental milestones.

• Translate platform capabilities, target biology, and program goals into executable experimental plans.

• Select appropriate discovery and screening approaches (e.g., display formats, selection stringency, screening depth) based on targetspecific requirements.

Laboratory Execution & Screening

• Execute handson laboratory experimentation supporting binder discovery and optimization, including cloning, expression, screening, and hit triage activities.

• Lead screening and downselection workflows, generating clear, decisionready data on binder performance (e.g., binding, specificity, functional activity).

• Perform experimental troubleshooting and iterative refinement of screening strategies based on data trends and program needs.

Data Interpretation & Program Contribution

• Analyze and interpret screening and characterization data to guide next experimental steps and optimization strategies.

• Communicate results, risks, and recommendations clearly to management and broader project teams.

• Contribute experimentally and scientifically to multiple discovery programs in parallel, balancing depth with throughput.

Collaboration & Platform Enablement

• Work closely with Associate Scientists and Research Associates to ensure efficient execution of experimental workflows.

• Collaborate with computational, Cell Biology, and Translational partners to align binder screening outputs with downstream assay and development needs.

• Provide experimental feedback that helps refine discovery platforms, screening assays, and campaign design principles.

Documentation & Scientific Rigor

• Maintain thorough experimental documentation using electronic lab notebooks and sampletracking systems (LIMS).

• Ensure reproducibility, traceability, and data integrity across all experimental activities.

• Contribute to a culture of rigorous experimental standards and continuous scientific improvement.

Basic Qualifications

• Advanced scientific degree (MD, PharmD, PhD)
  OR

• Master's degree with 4+ years of relevant scientific experience
  OR

• Bachelor's degree with 6+ years of relevant scientific experience

Preferred Qualifications

• PhD in Protein Science, Biochemistry, Structural Biology, Bioengineering, or a closely related discipline

• Strong handson experience in protein engineering, binder discovery, or related experimental workflows

• Demonstrated ability to design and execute experimental screening campaigns in a laboratory setting

• Experience generating and interpreting data to guide experimental decisions

• Experience with displaybased discovery platforms (e.g., phage, yeast, or related systems)

• Familiarity with binding and functional screening assays relevant to binder discovery

• Experience working in fastpaced, multiprogram discovery environments

• Strong scientific communication skills and comfort collaborating across disciplines

Attributes for Success

• Scientistexecutor who enjoys owning experiments from planning through data generation

• Comfortable balancing experimental design responsibilities with sustained bench work

• Thoughtful, datadriven decisionmaker who adapts strategies based on results

• Collaborative partner who works effectively with senior scientists and experimental teams

• Motivated by scientific progress, experimental rigor, and impact on discovery programs

This role is intended to serve as a key experimental and scientific driver of binder discovery and screening campaigns.

The salary range for this position is: $146,540.00 - $189,640.00. Kite considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

https://www.gilead.com/careers/compensation-benefits-and-wellbeing

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com. Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma.

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Kite Pharma is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability,genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contactApplicantAccommodations@gilead.com for assistance.

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