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Infographic showing various Project Manager job openings at Vir Biotechnology in the United States as of August 2026, with employment types broken down into 38% Full Time, and 62% Temporary. Highlights an 50% Physical, and 50% Remote job distribution.

Senior Director, Head of Clinical Pharmacology

Vir Biotechnology

San Francisco, CA • On-site

$235K - $329K/yr

Full-time

Medical, Retirement, PTO

Posted 9 days ago

Job description

THE OPPORTUNITY

Vir Biotechnology is looking for an experienced Sr. Director of Clinical Pharmacology to lead the technical and operational aspects of the department in support of programs across all stages of preclinical and clinical development. You will work across Vir Bio's portfolio of infectious disease and oncology programs, providing hands-on leadership while managing and developing a team. In this role, you will work collaboratively with internal and external cross-functional teams and consultants to support the successful and timely advancement of drug development programs. You will evaluate and apply best practices and innovative techniques to foster successful execution and outcomes of clinical studies. You will report to the VP of Translational Development.

This role is located in our San Francisco headquarters with an expectation of at least 3 days per week in office.

WHAT YOU'LL DO
  • Oversee clinical pharmacology and translational PK/PD operations and deliverables across all stages of development for both infectious disease and oncology programs
  • Represent clinical pharmacology and translational PK/PD as technical expert on cross-functional project teams and provide strategic input to program advancement
  • Develop fit-for-purpose clinical pharmacology strategies to enable development and regulatory decisions from pre-IND through market authorization
  • Select and execute appropriate modeling and simulation approaches (PK/PD, PopPK, exposure-response) to inform dose selection, optimization, and justification across all phases of drug development
  • Author and provide technical input for regulatory documents and submissions (protocols, IBs, briefing packages, INDs, NDAs/BLAs) and responses to questions
  • Work collaboratively with cross-functional teams, including clinical research, clinical operations, biomarkers, bioanalytical, biometrics, CMC, research, and regulatory in support of program advancement
  • Establish and manage collaborations with external vendors and collaborating partners
  • Generate and manage departmental budget(s) and optimize resource allocation across multiple programs
  • Manage and develop the Clinical Pharmacology and Translational PK/PD team, including hiring, mentoring, and building departmental capabilities to support organizational needs
WHO YOU ARE AND WHAT YOU BRING
  • PhD, PharmD, or MD with relevant training in clinical pharmacology, pharmacokinetics, pharmaceutics, or related field with 13+ years industry experience in Clinical Pharmacology, DMPK and/or related fields
  • Mastery of nonclinical and clinical pharmacokinetic concepts and methodologies with deep understanding of multidisciplinary drug development requirements
  • Expertise in PK/PD, PopPK and exposure-response modeling
  • Extensive experience leading translational and clinical pharmacology work from candidate selection through market authorization
  • Strong understanding of regulatory requirements and experience contributing to regulatory submissions and engagements
  • Working knowledge of bioanalytical techniques in support of clinical development of small molecules and biologics
  • Experience with biologics, including monoclonal antibodies and bispecifics required; experience in oncology indications strongly preferred
  • Proficiency using standard PK analysis and graphing programs
  • Proven ability to manage and develop teams
#LI-AS1
#LI-Onsite
WHO WE ARE AND WHAT WE OFFER

The expected salary range for this position is $235,500 to $329,500 per year. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors.

Vir Biotechnology's compensation and benefits are aligned with the current market and commensurate with the person's experience and qualifications. All full-time employees receive a package that includes compensation, bonus and equity as well as many other Vir Biotechnology benefits and perks such as health and welfare benefit plans, non-accrual paid time off, company shut down for holidays, commuter benefits, 401K match and lunch each day in the office.

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