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41 Natera Bioinformatics Engineer Jobs Hiring Near You

Natera

Principal Software Engineer

South San Francisco, CA · On-site

$162K - $217K/yr

... or bioinformatics computing, LIMS or laboratory data systems, workflow orchestration engines ... Work on the platform that powers Natera's R&D - a small, high-leverage team where individual ...

Natera

Principal Software Engineer

South San Francisco, CA · Remote

$162K - $217K/yr

... Engineer to join Natera's R&D Platform Infrastructure team. The team builds the cloud ... or bioinformatics computing, LIMS or laboratory data systems, workflow orchestration engines ...

Natera

Senior Product Manager, Clinical Genomics

$129K - $170K/yr

Senior Product Manager, Clinical Genomics Engineering Natera offers genetic risk assessment and ... Partner closely with software engineering, bioinformatics, clinical domain experts, quality ...

Natera

OR · On-site

$126K - $166K/yr

... bioinformatics software that allows detection down to a single molecule in a tube of blood. Natera ... You will work closely with business development, regulatory, engineering, design, and operations to ...

Natera

Quality Engineer

Boulder, CO

$74K - $96K/yr

Must maintain a current status on Natera training requirements. * Other duties as assigned ... Sequencing, Bioinformatics etc. * Demonstrated good judgment, excellent attention to detail ...

Natera

OR

Natera is hiring a Machine Learning Scientist to join our AI and computational biology team. This ... PhD in Computer Science, Computational Biology, Biomedical Engineering, Bioinformatics, Statistics ...

Natera

Design Transfer Scientist

San Carlos, CA · Hybrid

Join Natera's Bio Development Team as a Design Transfer Scientist to lead the transition of our ... automation engineering, laboratory operations, bioinformatics, statistics, project and product ...

Natera

OR · On-site

This is an exciting opportunity to independently lead Biostatistics efforts advancing Natera ... Partner with bench scientists, bioinformatics, and product development teams to integrate ...

Natera

Software Test Engineer

Boulder, CO · Hybrid

Bachelor's degree in a scientific discipline (e.g., Biology, Molecular Biology, Bioinformatics) or ... Experience working cross-functionally with engineering, bioinformatics, and quality teams

Natera

Senior Lab Systems Scientist

Boulder, CO

$94K - $129K/yr

The Senior Laboratory Systems Scientist will collaborate with R&D, Software, Bioinformatics, Laboratory Operations, Automation Engineering, and RA/QA to lead cross-functional initiatives including ...

Natera

Senior Lab Systems Scientist

Boulder, CO · On-site

$94K - $129K/yr

Collaborate with Automation Engineering, Bioinformatics, Supply Chain, Quality Assurance ... The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory ...

Natera

OR

PhD in Computer Science, Computational Biology, Bioinformatics, Biomedical Engineering, or a highly quantitative structural field * 5+ years of industry or post-doctoral experience applying deep ...

Natera

OR

Collaborate with laboratory operations, bioinformatics, and software teams to investigate root ... Partner with engineering and data science teams to evaluate software-related complaints and ...

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Natera Jobs Information

What is it like to work at Natera?

Natera is a company that prioritizes innovation and collaboration, fostering a culture of teamwork and open communication among its employees. The company's mission-driven approach is reflected in its work environment, where employees are encouraged to contribute to the development of non-invasive genetic testing technologies that improve patient care. Working at Natera may appeal to candidates who are passionate about advancing healthcare and are motivated by the opportunity to work on cutting-edge projects that have a direct impact on people's lives.

What makes Natera an attractive place to work?

Natera is a leading genetic testing and diagnostics company that plays a significant role in advancing personalized medicine and improving patient outcomes. The company's workplace is characterized by a culture of innovation, collaboration, and teamwork, with opportunities for employees to contribute to cutting-edge research and development, and work closely with cross-functional teams to drive business growth. Joining Natera offers professionals a chance to be part of a dynamic and forward-thinking organization, with opportunities for career growth, professional development, and making a meaningful impact in the field of genetic medicine.

Do workers at Natera get paid breaks?

Yes. Most people get paid breaks.
74% of people say they get paid breaks.
Based on data from 27 people who took the Breakroom Quiz between February 2025 and March 2026.

Does Natera pay people when they’re sick?

Yes. Most people get paid when they’re sick.
73% of people say they would get paid if they were sick but scheduled to work.
Based on data from 33 people who took the Breakroom Quiz between February 2025 and March 2026.

At Natera, are sick days and vacation days separate paid time off?

Sick days and vacation days are separate paid time off.
89% of people say they don’t have to use vacation days when they’re out sick.
Based on data from 19 people who took the Breakroom Quiz between May 2025 and March 2026.

Is the health insurance from Natera affordable enough for their workers?

Most people say the health insurance costs are okay.
92% of people say the health insurance costs are okay
Based on data from 25 people who took the Breakroom Quiz between March 2025 and March 2026.

Do people get paid time off at Natera?

Most people get paid time off work.
95% of people say they get paid time off.
Based on data from 22 people who took the Breakroom Quiz between May 2025 and March 2026.

How far ahead of time do people find out their work schedule?

Most people find out their schedule less than four weeks ahead of time.
  • 60% of people with changing schedules find out their shifts one week or less ahead of time.
  • 40% of people with changing schedules find out their shifts two weeks ahead of time.
  • 0% of people with changing schedules find out their shifts three weeks ahead of time.
  • 0% of people with changing schedules find out their shifts four weeks or more ahead of time.

Based on data from 5 people who took the Breakroom Quiz between April 2025 and July 2025.

Do workers at Natera worry about hours?

Most people don’t worry about getting enough hours.
90% of people report they don’t worry about getting enough hours.
Based on data from 20 people who took the Breakroom Quiz between February 2025 and September 2025.

Do Natera workers get to choose the shifts they work?

Some people don’t get to choose which shifts they work.
59% report that they don’t have enough control over which shifts they work.
Based on data from 17 people who took the Breakroom Quiz between February 2025 and September 2025.

How easy is it for Natera workers to change shifts?

Some people find it hard to change shifts.
36% of people report that it’s hard to change shifts if they need to.
Based on data from 11 people who took the Breakroom Quiz between February 2025 and August 2025.

How easy is it to get time off at Natera?

Most people find it easy to get time off.
70% of people report it’s easy to get time off.
Based on data from 30 people who took the Breakroom Quiz between February 2025 and March 2026.

Do Natera managers change schedules at the last minute?

Most managers don’t change people’s schedules at the last minute.
90% of people say their manager doesn’t change their shift schedule at the last minute.
Based on data from 20 people who took the Breakroom Quiz between February 2025 and September 2025.

Do jobs at Natera spill into time workers aren’t paid for?

Rarely. The job doesn't usually spill into unpaid time.
6% of people report that their job takes up time that they don’t get paid for.
Based on data from 17 people who took the Breakroom Quiz between February 2025 and September 2025.

How easy is it to take sick days at Natera?

Most people find it easy to take sick days.
79% of people report that it’s easy to take time off if they are sick.
Based on data from 33 people who took the Breakroom Quiz between February 2025 and March 2026.

Is working at Natera good if you’re a parent or caregiver?

Most parents and caregivers say this is a good place to work.
86% of people who care for a child or other relative report this is a good place to work.
Based on data from 7 people who took the Breakroom Quiz between April 2025 and March 2026.

Do people at Natera feel treated with respect by their managers?

Most people feel treated with respect by their managers.
84% of people say they’re treated with respect by their managers.
Based on data from 31 people who took the Breakroom Quiz between January 2025 and March 2026.

Do people at Natera get to take their breaks without interruption?

Most people get breaks without interruption.
90% of people report that they get to take their breaks without interruption.
Based on data from 29 people who took the Breakroom Quiz between January 2025 and March 2026.

Is it stressful to work at Natera?

Most people feel stressed out here.
70% of people say they often feel stressed out at work.
Based on data from 33 people who took the Breakroom Quiz between January 2025 and March 2026.

Do people at Natera enjoy their jobs?

Most people enjoy their job.
69% of people report they enjoy their job.
Based on data from 26 people who took the Breakroom Quiz between January 2025 and March 2026.

Do people at Natera recommend working with their team?

Only some people recommend working with their team.
40% of people report that they wouldn’t recommend working with their immediate team to a friend.
Based on data from 30 people who took the Breakroom Quiz between March 2025 and March 2026.

Do people get enough training when they start at Natera?

Most people got enough training when they started.
74% of people report they got enough training when they started working here.
Based on data from 34 people who took the Breakroom Quiz between January 2025 and March 2026.

Do people get support to advance at Natera?

Most people are given support to advance their career here.
In the last year, 68% of people report being given support to advance their career here.
Based on data from 28 people who took the Breakroom Quiz between January 2025 and March 2026.

Do people think Natera’s headquarters understands what’s happening where they work?

Most people think headquarters doesn’t understand what’s happening where they work.
70% of people think that this employer’s headquarters or owners don’t have a good understanding of what’s really happening where they work.
Based on data from 30 people who took the Breakroom Quiz between January 2025 and March 2026.

Do workers feel well informed about how Natera is doing?

Most people feel well informed about how the company is doing.
71% of people feel that they are kept well informed about how the company is doing as a whole.
Based on data from 31 people who took the Breakroom Quiz between January 2025 and March 2026.
What other companies are hiring for Bioinformatics Engineer jobs?
What are the most popular jobs at Natera?
What are the most popular categories at Natera?
Infographic showing various Bioinformatics Engineer job openings at Natera in the United States as of July 2026, with employment types broken down into 1% As Needed, 93% Full Time, 3% Part Time, 2% Temporary, and 1% Contract. Highlights an 70% Physical, 1% Hybrid, and 29% Remote job distribution.
Principal Software Engineer

Principal Software Engineer

Natera

South San Francisco, CA • On-site

$162K - $217K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 28 days ago

Natera rating

7.7

Company rating: 7.7 out of 10

Based on 35 frontline employees who took The Breakroom Quiz

51st of 105 rated laboratories

Job description

Job Title: Principal Software Engineer
Location: South San Francisco, CA preferred; Remote optional
Job Type: Full-time
About the Role
We're seeking a Principal Software Engineer to join Natera's R&D Platform Infrastructure team. The team builds the cloud infrastructure, workflow platforms, and data platforms that R&D uses to do its science - including a Kubernetes-based workflow execution platform, a custom R&D LIMS system, and a set of supporting tools that routinely handle production-scale workloads.
This is a senior technical role. You'll own the full architecture, implementation, and delivery of large projects across our platform. You'll partner with the team lead on roadmap and tough technical calls, mentor mid-level engineers, and help the team find the right solution for the problem - not the most elaborate one. We're a small team (4 engineers + lead) with broad scope, and we're heavily AI-augmented: every engineer uses Claude Code / Cursor as a daily tool, and we build our own AI tooling (custom plugins, MCP servers, agents) to multiply ourselves.
Responsibilities
  • Architecture & Delivery: Own the design, implementation, and delivery of major initiatives across our platform. Take fuzzy problems through to shipped, working software used in production.
  • Technical Leadership: Lead architecture and design reviews. Help the team find the right solution for the problem and avoid unnecessary complexity. Influence technical decisions across the team.
  • Mentorship: Mentor mid-level engineers through code review, design docs, and pairing. Raise the engineering bar by example.
  • AI-Native Development: Build and improve our AI-coding tooling alongside the rest of the team. Help us push the frontier of agent-driven software development inside the company.
  • Cross-Functional Partnership: Work with bioinformaticians, scientists, and other R&D engineers to understand their needs and translate them into platform capabilities. Partner with the team lead on roadmap, prioritization, and tough technical calls.
Required Experience
  • Years of Experience: 10+ years of professional software engineering experience across a range of systems and problem types.
  • Cloud Infrastructure: Production experience with a major cloud platform (AWS preferred; GCP or Azure equivalent). You've designed for a cloud, not just deployed to one.
  • Container Orchestration: Production experience with Kubernetes (or equivalent). Comfortable reasoning about cluster design, scheduling, networking, and workload patterns.
  • Infrastructure as Code: Production experience with Terraform (or equivalent). Comfortable owning shared modules and multi-environment deployments.
  • Programming: Strong proficiency in at least one general-purpose language (Python, Go, Java, or similar). Comfortable picking up new languages as needed - and comfortable using AI tooling to accelerate that.
  • End-User Software: You've shipped software to end users (internal or external). You understand the realities of running a product - incongruent user feedback, competing priorities, the gap between requirements and what users actually need.
  • Team Leadership: You've led an engineering team before and have mentored junior engineers. You're comfortable being the technical owner of multi-quarter initiatives.
  • Startup Background: You've worked in fast-moving environments where results need to be delivered quickly. Scrappy, MVP-first, comfortable shipping in days rather than weeks.
  • Familiarity with our tech stack: AWS, Kubernetes, Python, Go, Groovy, Terraform, Helm, Nextflow, WDL, Django, React.
How You Work
  • Product-Minded: You think in terms of business and user problems, not tickets. You ask "should we build this?" before "how do I build this?"
  • Calibrated Judgement: You know when to move fast and break things, and when to slow down and double-check. The ability to dial this in based on context is something we hire specifically for.
  • AI-Native Development: Actively excited about AI-native development. Not just willing to use Claude / Cursor, but actively interested in building tooling that makes your colleagues 10x faster.
Bonus
  • Domain-Adjacent Experience: Prior work in any of the following helps you ramp faster, but is not required: scientific or bioinformatics computing, LIMS or laboratory data systems, workflow orchestration engines (Nextflow, WDL, Airflow, Argo, Temporal, Dagster, etc.), large-scale ETL or data pipeline systems, or HPC/batch-compute platforms.
Why Join Us
  • Work on the platform that powers Natera's R&D - a small, high-leverage team where individual contribution is highly visible.
  • Operate at the frontier of AI-augmented software engineering. We don't just talk about AI tooling - we build it, and use it daily.
  • Significant autonomy and influence over the team's technical direction.
  • Competitive salary and benefits.

We value diversity and are committed to creating an inclusive environment for all employees. We encourage applicants of all backgrounds to apply.
Compensation & Total Rewards
This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.
This position is also eligible for additional compensation and benefits through Natera's robust Total Rewards program, including:
  • Annual performance incentive bonus
  • Long-term equity awards
  • Comprehensive health benefits (medical, dental, vision)
  • 401(k) with company match
  • Generous paid time off and company holidays
  • Additional wellness and work-life benefits

Compensation Range
$219,800-$274,700 USD
OUR OPPORTUNITY
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women's health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you'll work hard and grow quickly. Working alongside the elite of the industry, you'll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
If you are based in California, we encourage you to read this important information for California residents.
Link: https://www.natera.com/notice-of-data-collection-california-residents/
Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.
For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page

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