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Weekend Rn Jobs in St Louis, MO (NOW HIRING)

TotalMed RN

Travel ER RN

Belleville, IL · On-site

TotalMed RN is seeking a travel nurse RN ED - Emergency Department for a travel nursing job in Belleville, Illinois. & Requirements * Specialty: ED - Emergency Department * Discipline: RN * Start ...

TotalMed RN

Travel ER RN

Maryville, IL · On-site

TotalMed RN is seeking a travel nurse RN ED - Emergency Department for a travel nursing job in Maryville, Illinois. & Requirements * Specialty: ED - Emergency Department * Discipline: RN * Duration ...

TotalMed RN

Travel OR RN

Saint Louis, MO · On-site

TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Saint Louis, Missouri. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Duration: 8 weeks ...

TotalMed RN

Travel OR RN

Saint Louis, MO · On-site

TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Saint Louis, Missouri. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Start Date: 09/28 ...

TotalMed RN

Travel ER RN

Saint Louis, MO · On-site

TotalMed RN is seeking a travel nurse RN ED - Emergency Department for a travel nursing job in Saint Louis, Missouri. & Requirements * Specialty: ED - Emergency Department * Discipline: RN * Start ...

TotalMed RN

Travel RN First Assist

Saint Louis, MO · On-site

TotalMed RN is seeking a travel nurse RN First Assist for a travel nursing job in Saint Louis, Missouri. & Requirements * Specialty: First Assist * Discipline: RN * Duration: 13 weeks * 40 hours per ...

TotalMed RN

Travel OR RN

Saint Louis, MO · On-site

TotalMed RN is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Saint Louis, Missouri. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Start Date: ASAP

TotalMed RN

Travel Home Health RN

Saint Louis, MO · On-site

TotalMed RN is seeking a travel nurse RN Home Health for a travel nursing job in Saint Louis, Missouri. & Requirements * Specialty: Home Health * Discipline: RN * Duration: 13 weeks * 40 hours per ...

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All JobsRn JobsWeekend Rn JobsWeekend Rn Jobs in St. Louis, MO

Weekend Rn information

See St Louis, MO salary details

$26

$41

$69

How much do weekend rn jobs pay per hour?

As of Sep 15, 2026, the average hourly pay for weekend rn in St. Louis, MO is $41.55, according to ZipRecruiter salary data. Most workers in this role earn between $32.97 and $47.96 per hour, depending on experience, location, and employer.

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

What does a Weekend RN do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

More about Weekend Rn jobs

What are the most commonly searched types of Rn jobs in St. Louis, MO?

The most popular types of Rn jobs in St. Louis, MO are:

What are popular job titles related to Weekend Rn jobs in St. Louis, MO?

For Weekend Rn jobs in St. Louis, MO, the most frequently searched job titles are:

What job categories do people searching Weekend Rn jobs in St. Louis, MO look for?

The top searched job categories for Weekend Rn jobs in St. Louis, MO are:

What cities near St. Louis, MO are hiring for Weekend Rn jobs?

Cities near St. Louis, MO with the most Weekend Rn job openings:

Weekend Rn jobs near you
Infographic showing various Weekend Rn job openings in St. Louis, MO as of September 2026, with employment types broken down into 77% Full Time, 17% Part Time, and 6% Temporary. Highlights an 94% In-person, and 6% Remote job distribution, with an average salary of $86,416 per year, or $41.5 per hour.

Registered Nurse - RN - St. Louis Rehab Hospital

Chesterfield, MO • On-site

Mercy
Health Care and Social Assistance • 10K+ employees
Learn more about Mercyexternal

$20K/mo

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 11 days ago

Mercy rating

6.5

Company rating: 6.5 out of 10

Based on 209 frontline employees who took The Breakroom Quiz

Job description

Find your calling at Mercy! Utilizes the nursing process to provide patient care. Maintains professional accountability for provision of patient care for the assigned patients. Evaluates the overall effectiveness of care provided by other direct care givers. Coordinates the patient care in conjunction with other departments. Maintains patient rights and confidentiality of patient information. Performs duties and responsibilities in a manner consistent with our mission, values, and Mercy Service Standards. Position Details: Join Mercy Rehabilitation Hospital!

Location: Chesterfield Missouri (St. Louis Area)

$10,000 SIGN ON BONUS FOR EXPERIENCED RNs! $5,000 SIGN ON BONUS FOR NEW GRAD RNs! Part-time and Full-time RN opportunities available! 12 hour shifts - Nights

Experienced RN Incentives:

  • Up to $10,000 Sign-On Bonus

    • No Contract Required!

  • ASN to BSN Bridging Program to assist in obtaining your BSN (up to $16,000).

  • BSN to MSN Bridging Program to assist in obtaining your MSN (up to $16,000).

New RN Incentives:

  • Up to $5,000 Sign-On Bonus

    • No Contract Required!

  • RN Loan Forgiveness Program to aide in paying off your RN student loan debt.

    • Up to $370 per month directly towards loan payments ($20,000 cap).

    • Must start with Mercy within 12-months of graduation

We Offer Great Benefits:


Day-one comprehensive health, vision and dental coverage, PTO, tuition reimbursement and employer-matched retirement funds are just a few of the great benefits offered to eligible co-workers, including those working 48 hours or more per pay period!

  • Shift Differential Pay

  • Annual Merit increases based on performance

  • Tuition Reimbursement up to $2,000 for continuing education

  • Health/Dental/Vision available after day one

  • Annual contribution of $100 per month to eligible co-workers enrolled in the Dependent Care FSA

  • Paid parental leave for new parents

  • 401k with employer match

  • Paid PTO for volunteering

  • Competitive salary

RESTORING HOPE IS THE GOAL FOR EVERY PATIENT WE SERVE

Mercy Rehabilitation Hospital St. Louis is a state-of-the-art facility designed specifically for patients requiring inpatient rehabilitation services. We offer programs that range from single therapies to comprehensive, multidisciplinary programs for patients recovering from strokes, brain or spinal-cord injuries, amputations, burns, orthopedic injuries and other conditions. We provide rehabilitative care to patients and families utilizing a team approach, with an emphasis on improving individual functional ability and quality of life. Our Treatment Team includes experienced Rehabilitation Nurses who provide excellent service and around-the-clock compassionate nursing care in an exceptional work environment.

  • 81 private rooms

  • Therapy Gym in each unit

  • On-site Dialysis Suite

  • Dedicated Nursing Assistant for each Nursing team

Qualifications:

  • Required Education: Nursing Degree from an accredited RN program.

  • Preferred Education: BSN

  • License: current RN license in the state of MO.

  • Certifications: Basic Life Support certification through the American Heart Association

Why Mercy?

From day one, Mercy offers outstanding benefits - including medical, dental, and vision coverage, paid time off, tuition support, and matched retirement plans for team members working 32+ hours per pay period.

Join a caring, collaborative team where your voice matters. At Mercy, you'll help shape the future of healthcare through innovation, technology, and compassion. As we grow, you'll grow with us.


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What Mercy employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom

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About Mercy

Sourced by ZipRecruiter

Our mission is clear. We bring to life a healing ministry through our compassionate care and exceptional service. At Mercy, we believe in careers that match the unique gifts of unique individuals - careers that not only make the most of your skills and talents, but also your heart.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Chesterfield, MO, US

Year founded

1827

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