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Weekend Rn Jobs in St Louis, MO (NOW HIRING)

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Weekend Rn information

See St Louis, MO salary details

$26

$41

$69

How much do weekend rn jobs pay per hour?

As of Aug 7, 2026, the average hourly pay for weekend rn in St. Louis, MO is $41.55, according to ZipRecruiter salary data. Most workers in this role earn between $32.97 and $47.96 per hour, depending on experience, location, and employer.

What does a Weekend RN do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.
More about Weekend Rn jobs
What are the most commonly searched types of Rn jobs in St. Louis, MO? The most popular types of Rn jobs in St. Louis, MO are:
What are popular job titles related to Weekend Rn jobs in St. Louis, MO? For Weekend Rn jobs in St. Louis, MO, the most frequently searched job titles are:
What job categories do people searching Weekend Rn jobs in St. Louis, MO look for? The top searched job categories for Weekend Rn jobs in St. Louis, MO are:
What cities near St. Louis, MO are hiring for Weekend Rn jobs? Cities near St. Louis, MO with the most Weekend Rn job openings:
Weekend Rn jobs near you
Infographic showing various Weekend Rn job openings in St. Louis, MO as of August 2026, with employment types broken down into 74% Full Time, 13% Part Time, and 13% Contract. Highlights an 100% In-person job distribution, with an average salary of $86,416 per year, or $41.5 per hour.

RN/LPN Weekend Nights

Advantage Nursing Services

Belleville, IL • On-site

$26.50 - $36/hr

Other

Medical, Dental, Vision, PTO

Re-posted 15 days ago

Job description

RN/LPN Weekend Nights

Homecare Nurses Needed for Weekend Nights in Belleville, IL!

Friday & Saturday; 4:00pm-11:00pm OR 7:30pm-8:00am

Are you looking for a flexible schedule, weekly pay, and a healthy work/life balance?

Advantage Nursing Services is dedicated to providing reliable, high-quality and compassionate health care to children and adults in the comfort of their home!

No pediatric or private-duty nursing experience required!

Full-time, Part-time, and PRN Hours Available Immediately!

  • Flexible Schedules
  • Weekly Pay with Direct Deposit
  • Nurse Referral Bonus Program
  • Paid Vacation
  • 24/7 RN Support
  • Health Benefits including Medical, Dental, Vision, and more!

Responsibilities

  • 1 on 1 Patient Care.
  • Provide nursing care in accordance with the physician's care plan of treatment.
  • Monitor patient's condition and compose patient charts.
  • Assist patient in daily activities.
  • Take and record vitals.
  • Provide caregiver relief.

Requirements

  • Active IL NURSING LICENSE
  • Current CPR Certification

Interested in learning more?

Call 1-800-830-2737 to speak to a Recruiter or visit our website at ANSjobs.com!

Apply