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Overnight Rn Jobs in St Louis, MO (NOW HIRING)

Nexus at Cahokia

Registered Nurse (RN)

Cahokia, IL · On-site

$40 - $45/hr

As a Registered Nurse (RN), you will be responsible for providing high-quality resident care. You ... Overnight Shift- 7pm to 7am Key Responsibilities: * Administer medications and treatments safely ...

Nexus Health Management

Registered Nurse (RN)

Cahokia, IL · On-site

$40 - $45/hr

Overnight Shift- 7pm to 7am Key Responsibilities: * Administer medications and treatments safely ... Registered Nurse (RN) Preferred Qualifications: * Active Registered Nurse (RN) license in the State ...

BRIA Health Services

Registered Nurse (RN)

Cahokia, IL · On-site

$40 - $45/hr

As a Registered Nurse (RN), you will be responsible for providing high-quality resident care. You ... Overnight Shift- 7pm to 7am Key Responsibilities: * Administer medications and treatments safely ...

Arch Vista

RN Night

Saint Louis, MO

$30 - $42/hr

In this Overnight Psychiatric RN role, you'll oversee patient care, ensure safety, and make critical clinical decisions in a quieter--but no less important--setting. Key Responsibilities * Complete ...

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Overnight Rn information

See St Louis, MO salary details

$23

$55

$107

How much do overnight rn jobs pay per hour?

As of Aug 28, 2026, the average hourly pay for overnight rn in St. Louis, MO is $55.64, according to ZipRecruiter salary data. Most workers in this role earn between $37.40 and $62.64 per hour, depending on experience, location, and employer.

What is an overnight RN?

Overnight Registered Nurses (RNs) are licensed nursing professionals who work night shifts in healthcare settings such as hospitals, nursing homes, or clinics. Their responsibilities include monitoring patient health, administering medications, responding to emergencies, and collaborating with other staff to provide continuous care during overnight hours. Working overnight requires strong attention to detail, adaptability, and the ability to work independently. These nurses play a critical role in ensuring patient safety and care throughout the night when staffing is often reduced.

What are the key skills and qualifications needed to thrive as an overnight RN?

To thrive as an Overnight RN, you need a solid background in clinical nursing, acute care skills, and an active RN license, often accompanied by experience in night shift or critical care environments. Familiarity with electronic health records (EHR), medication administration systems, and bedside monitoring technology is essential. Strong organization, resilience, and effective communication are vital soft skills for handling high-pressure situations and working with patients and limited overnight staff. These competencies ensure safe, high-quality patient care and efficient operations during overnight hours when resources and support may be reduced.

What unique challenges do overnight RNs face compared to day-shift nurses?

Overnight RNs often encounter unique challenges such as managing fatigue and adapting to disrupted sleep patterns, which can impact alertness and decision-making. They typically work with reduced staffing levels and fewer support resources, requiring a higher degree of autonomy and strong critical thinking skills. Additionally, overnight RNs may perform more independent assessments and handle emergencies until daytime teams arrive, making adaptability and effective communication with both patients and incoming staff essential.

What are the most commonly searched types of Rn jobs in St. Louis, MO?

The most popular types of Rn jobs in St. Louis, MO are:

What cities near St. Louis, MO are hiring for Overnight Rn jobs?

Cities near St. Louis, MO with the most Overnight Rn job openings:

Overnight Rn jobs near you
Infographic showing various Overnight Rn job openings in St. Louis, MO as of August 2026, with employment types broken down into 50% Full Time, and 50% Part Time. Highlights an 100% In-person job distribution, with an average salary of $115,724 per year, or $55.6 per hour.

Registered Nurse (RN)

Cahokia, IL • On-site

Nexus at Cahokia
See more jobs at Nexus at Cahokiaexternal

$40 - $45/hr

Full-time, Per diem

Medical, Dental, Vision, Retirement, PTO

Re-posted 5 days ago

Job description

Description

Position Overview: As a Registered Nurse (RN), you will be responsible for providing high-quality resident care. You will assess patient needs, implement care plans, and collaborate with other team members to ensure best outcomes. 


Available Schedule:

Full Time or PRN: Day Shift- 7am to 7pm

Full Time or PRN: Overnight Shift- 7pm to 7am


Key Responsibilities: 

  • Administer medications and treatments safely and accurately
  • Monitor patient progress and document clinical findings
  • Collaborate with physicians, specialists, and healthcare staff
  • Educate patients and families on health conditions, treatments, and post-care instructions

Benefits Offered:

  • Low-cost Medical, Dental & Vision Insurance - Quality coverage options to fit your needs and budget
  • Short- & Long-Term Disability Coverage - Financial protection and peace of mind
  • 401(k) with Company Match - Invest in your future with employer contributions
  • Generous Paid Time Off - Includes vacation days, sick time, and paid holidays
  • Tuition Reimbursement - Advance your education and grow your career
  • Career Growth Opportunities - We prioritize internal promotions and professional development
  • Employee Rewards & Recognition Programs - Celebrating your hard work regularly
  • Weekly & Monthly Appreciation Events - Because your efforts deserve recognition
  • Birthday & Work Anniversary Celebrations - We celebrate you
  • Collaborative, Team-Oriented Culture - Work alongside supportive and dedicated colleagues


Requirements

 Registered Nurse (RN) Preferred Qualifications:

  • Active Registered Nurse (RN) license in the State of Illinois
  • Associate or bachelor's degree in nursing (BSN preferred)
  • Current BLS certification (ACLS preferred, depending on role)
  • Strong clinical judgment and critical thinking skills


Apply