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Weekend Prn Rn Jobs in North Charleston, SC (NOW HIRING)

PruittHealth

PRN Registered Nurse RN Hospice

Ladson, SC · On-site

$55.10 - $68.88/hr

- PRN Registered Nurse RN Hospice (2609407)PRN Registered Nurse RN Hospice - 2609407DescriptionREGISTERED NURSE (RN) CASE MANAGER - HOSPICE SERVICES - PRN Available Join the PruittHealth Hospice family ...

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Weekend Prn Rn information

See North Charleston, SC salary details

$18

$34

$51

How much do weekend prn rn jobs pay per hour?

As of Sep 2, 2026, the average hourly pay for weekend prn rn in North Charleston, SC is $34.80, according to ZipRecruiter salary data. Most workers in this role earn between $27.74 and $40.14 per hour, depending on experience, location, and employer.

What is a Weekend PRN RN?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

What are the typical shift expectations and workload for a Weekend PRN RN?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend PRN RN position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

Do PRN registered nurses have to work weekends?

PRN registered nurses are scheduled on an as-needed basis and are not typically required to work weekends unless assigned to weekend shifts. Their work schedule depends on the facility's staffing needs and the nurse's availability, often offering flexibility. However, some PRN positions may include weekend shifts if the facility requires coverage during those times.

What are the most commonly searched types of Prn Rn jobs in North Charleston, SC?

The most popular types of Prn Rn jobs in North Charleston, SC are:

What are popular job titles related to Weekend Prn Rn jobs in North Charleston, SC?

For Weekend Prn Rn jobs in North Charleston, SC, the most frequently searched job titles are:

What job categories do people searching Weekend Prn Rn jobs in North Charleston, SC look for?

The top searched job categories for Weekend Prn Rn jobs in North Charleston, SC are:

What cities near North Charleston, SC are hiring for Weekend Prn Rn jobs?

Cities near North Charleston, SC with the most Weekend Prn Rn job openings:

Weekend Prn Rn jobs near you
Infographic showing various Weekend Prn Rn job openings in North Charleston, SC as of August 2026, with employment types broken down into 1% As Needed, 68% Full Time, 25% Part Time, 5% Contract, and 1% Nights. Highlights an 93% Physical, 1% Hybrid, and 6% Remote job distribution, with an average salary of $72,375 per year, or $34.8 per hour.

PRN Registered Nurse

Interim HealthCare - North Charleston, SC

Mount Pleasant, SC

$38/hr

Per diem

Posted 8 days ago

Job description

PRN Registered Nurse (RN) – Medication Pass Nurse

Interim HealthCare is seeking a compassionate and dependable Registered Nurse (RN) to join our team as a PRN Medication Pass Nurse. This flexible PRN opportunity is ideal for an RN looking to supplement their current schedule while making a meaningful impact on patient care.

Proudly Celebrating 60 Years of Impact & 20 Years of Local Service and Excellence 

 

Position Overview

The PRN Medication Pass Nurse will be responsible for safely administering medications, monitoring patient responses, and providing skilled nursing support during designated medication administration hours.

As a PRN Medication Pass Nurse, here’s a big-picture view of what you’ll do:

  • Administer prescribed medications safely and accurately
  • Monitor patients for adverse reactions and medication effectiveness
  • Maintain accurate medication administration records (MARs)
  • Communicate patient concerns and changes in condition to appropriate team members
  • Follow all nursing standards, policies, and regulatory requirements
  • Provide compassionate, patient-centered care

The proposed schedule for the PRN Medication Pass Nurse is as follows:

  • PRN position
  • 4-hour shifts - 11am to 3pm 
  • 3 days per week - Tuesday, Wednesday, and Thursdays 

Our Medication Pass RNs enjoy some notable benefits:                            

  • Competitive pay: $38.00/hour
  • Weekly pay
  • Comprehensive On-boarding and Training 
  • Supportive Management with Career Growth Opportunities 

A few must-haves for our Medication Pass RNs:

  • Graduate of an accredited school of nursing and current RN License in SC or compact license.
  • Proficient computers skills and workplace software knowledge.
  • Work with people, function well under stress, use clinical judgment, be creative and accept challenges.
  • Current CPR certification
  • Strong clinical assessment and communication skills
  • Ability to work independently and manage time effectively
  • Medication administration experience preferred
  • Valid driver's license and proof of insurance   

Why Work for Interim HealthCare?

Founded in 1966, Interim HealthCare is the nation’s first home care company and a leading employer of Registered Nurses (RNs). Operating through 300+ offices, our commitment to nurses is expressed through our passion to put patients first; a culture that values and appreciates nurses; and our ongoing efforts to advocate for nurses in ways that elevate their profession and reward their sacrificial work. Join a nationwide network of nurses who have rediscovered the passion that led them to nursing.

Interim HealthCare provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, gender, religion, sexual orientation, national origin, age, disability or veteran status.

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