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Weekend Prn Rn Jobs in Bluffton, SC (NOW HIRING)

PRN Healthcare is seeking a travel nurse RN PCU - Progressive Care Unit for a travel nursing job in Beaufort, South Carolina. & Requirements * Specialty: PCU - Progressive Care Unit * Discipline: RN ...

PRN Healthcare is seeking a travel nurse RN PCU - Progressive Care Unit for a travel nursing job in Beaufort, South Carolina. & Requirements * Specialty: PCU - Progressive Care Unit * Discipline: RN ...

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Weekend Prn Rn information

See Bluffton, SC salary details

$18

$33

$50

How much do weekend prn rn jobs pay per hour?

As of Aug 10, 2026, the average hourly pay for weekend prn rn in Bluffton, SC is $33.98, according to ZipRecruiter salary data. Most workers in this role earn between $27.12 and $39.18 per hour, depending on experience, location, and employer.

What are the typical shift expectations and workload for a Weekend PRN RN?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend PRN RN position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

What is a Weekend PRN RN?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

What are popular job titles related to Weekend Prn Rn jobs in Bluffton, SC? For Weekend Prn Rn jobs in Bluffton, SC, the most frequently searched job titles are:
What cities near Bluffton, SC are hiring for Weekend Prn Rn jobs? Cities near Bluffton, SC with the most Weekend Prn Rn job openings:
Infographic showing various Weekend Prn Rn job openings in Bluffton, SC as of August 2026, with employment types broken down into 1% As Needed, 69% Full Time, 25% Part Time, 4% Contract, and 1% Nights. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $70,679 per year, or $34 per hour.

Other

Medical, Dental, Vision, Life, Retirement, PTO

Posted 19 days ago


Job description

Do you have the career opportunities as a PRN RN Infusion you want with your current employer? We have an exciting opportunity for you to join HCA Healthcare Trident Hospital which is part of the nation's leading provider of healthcare services, HCA Healthcare.

Job Summary and Qualifications

Under general supervision the Infusion RN staff nurse provides direct nursing care in accordance with established policies and procedures of Trident Health System. In collaboration with the patient, the patient’s family and other members of the health care team, the clinical RN assesses, plans, implements, evaluates, and coordinates treatment plans. Retrieve blood products and pharmaceuticals from pharmacy. Billing and ensure inventory is sufficient. Job may include direct supervision of students at the discretion of the area supervisor. Employee must have the same licensure or have completed the same training to satisfy the requirements of the discipline of the student. Direct supervision means the primary caregiver is readily available to the student throughout the shift.

Additional responsibilities:

  •  Perform effectively and efficiently all the procedures in the clinic areas.
  • Responsible for cleaning, maintenance, and storage of equipment, with inspection to assure its readiness for use (sterilized or clean).
  • Make notes or dictate notes of patient’s daily progress.
  • Capable of assisting in other areas of department when need arises.
  • Must be proficient in operating a computer and operating specific applications such as MediTec and MOSAIQ.
  • Schedule and coordinate patient appointments
  • Participant in patient teaching.
  • Participate in facilitating community events and support groups.
What qualifications you will need:
  • Current license as a registered Nurse to practice in the State of South Carolina.

  • BLS – Healthcare provider. 

  • Chemotherapy/Biotherapy Certification by ONS (this certification course should be completed with 3 months of date of hire)

  • Graduate of a NLN accredited school of nursing.

  • Experience in Oncology or an Infusion Suite.

Benefits

HCA Healthcare Trident Hospital, offers a total rewards package that supports the health, life, career and retirement of our colleagues. The available plans and programs include:

  • Comprehensive benefits for medical, prescription drug, dental, vision, behavioral health and telemedicine services
  • Wellbeing support, including free counseling and referral services
  • Time away from work programs for paid time off, paid family leave, long- and short-term disability coverage and leaves of absence
  • Savings and retirement resources, including a 401(k) Plan with a 100% match on 3% to 9% of pay (based on years of service), Employee Stock Purchase Plan, flexible spending accounts, preferred banking partnerships, retirement readiness tools, rollover support and financial wellbeing counseling
  • Education support through tuition assistance, student loan assistance, certification support, dependent scholarships and a partnership with Galen College of Nursing
  • Additional benefits for fertility and family building, adoption assistance, life insurance, supplemental health protection plans, auto and home insurance, legal counseling, identity theft protection and consumer discounts

Learn more about Employee Benefits

Note: Eligibility for benefits may vary by location.

Trident Medical Center – Facility Overview

Founded in 1975, Trident Medical Center has been serving patients and families throughout Berkeley, Charleston, and Dorchester Counties for 50 years. As a 320+ bed Level II Trauma Center, Trident provides comprehensive healthcare services, advanced specialty care, and 24/7 emergency treatment, earning recognition as the #1 Trauma Center in the Lowcountry.

Key Highlights

  • Award-winning Heart Center
  • Home to the South Carolina Institute for Robotic Surgery
  • Comprehensive breast health services through the Trident Breast Care Center
  • Features the Joseph M. Still Burn Clinic, the region’s only outpatient burn clinic for patients of all ages
  • Provides 24/7 Hospitalist and Intensivist coverage
  • Healthgrades Five-Star recipient for cardiovascular care, neurosciences, critical care, and patient safety outcomes

Expanded Emergency Access
In addition to emergency departments at Trident Medical Center and Summerville Medical Center, the health system operates four freestanding emergency rooms (FSERs) offering 24/7 emergency care:

  • Brighton Park Emergency (Summerville)
  • Centre Pointe Emergency (North Charleston)
  • James Island Emergency (Charleston)
  • Moncks Corner Medical Center (Berkeley County)
  • Long Point Free Standing ED coming soon!

Together, these facilities provide convenient, around-the-clock access to emergency services across the greater Charleston region.

"Bricks and mortar do not make a hospital. People do."- Dr. Thomas Frist, Sr.
HCA Healthcare Co-Founder

If you are looking for an opportunity that provides satisfaction and personal growth, we encourage you to apply for our PRN RN Infusion opening. We promptly review all applications. Highly qualified candidates will be contacted for interviews. Unlock the possibilities and apply today!

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.