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Weekend Lab Jobs in Colorado (NOW HIRING)

Medical Lab Technologist

Meeker, CO · On-site

$40 - $43/hr

Medical Lab Technologist Location: Meeker, Colorado Pay Rate: $40 to $43/hr Contract: 13 Weeks ... Rotate weekday call and every fourth weekend call as required. Requirements * Current active state ...

Experienced Lab Technologist needed with 10 + years of lab experience to perform diagnostic ... Must rotate call weekdays plus every fourth weekend._**NO EXCEPTIONS ON REQUIREMENTS**_ _**MUST ...

Medlivo is seeking a travel Medical Lab Technician for a travel job in Wray, Colorado ... Schedule: 4×10-hour shifts | Shared call for nights and weekends | Generally 1 weekend of call per ...

Lab Tech

Rifle, CO · On-site

$20.25 - $26.75/hr

Lab Tech (MT/MLT/MLS) PRN Grand River Health | Rifle, CO At Grand River, we are more than a ... Shift Differentials: $2-$4/hour for nights and weekends. 10% PRN differential Compensation may vary ...

Lab Tech

Rifle, CO · On-site

$20.25 - $26.75/hr

Lab Tech (MT/MLT/MLS) PRN Grand River Health | Rifle, CO At Grand River, we are more than a ... Shift Differentials: $2-$4/hour for nights and weekends. 10% PRN differential Compensation may vary ...

Lab Tech (MT/MLT/MLS) PRN Grand River Health | Rifle, CO At Grand River, we are more than a ... Shift Differentials: $2-$4/hour for nights and weekends. 10% PRN differential Compensation may vary ...

Lab Tech

Rifle, CO · On-site

$20.25 - $26.75/hr

Lab Tech (MT/MLT/MLS) PRN Grand River Health | Rifle, CO At Grand River, we are more than a ... Shift Differentials: $2-$4/hour for nights and weekends. 10% PRN differential Compensation may vary ...

Lab Tech (MT/MLT/MLS) PRN Grand River Health | Rifle, CO At Grand River, we are more than a ... Shift Differentials: $2-$4/hour for nights and weekends. 10% PRN differential Compensation may vary ...

Lab Tech

Rifle, CO · On-site

$27.79 - $46.20/hr

Lab Tech (MT/MLT/MLS) FT, Days (7 on/ 7 off) Grand River Health | Rifle, CO At Grand River, we are ... Shift Differentials: $2-4/hour for nights and weekends * Comprehensive Benefits: Medical, dental ...

Lab Tech

Rifle, CO · On-site

$27.79 - $46.20/hr

Lab Tech (MT/MLT/MLS) FT, Days (7 on/ 7 off) Grand River Health | Rifle, CO At Grand River, we are ... Shift Differentials: $2-$4/hour for nights and weekends * Comprehensive Benefits: Medical, dental ...

Lab Tech

Rifle, CO · On-site

$27.79 - $46.20/hr

Lab Tech (MT/MLT/MLS) FT, Days (7 on/ 7 off) Grand River Health | Rifle, CO At Grand River, we are ... Shift Differentials: $2-$4/hour for nights and weekends * Comprehensive Benefits: Medical, dental ...

Lab Tech

Rifle, CO · On-site

$27.79 - $46.20/hr

Lab Tech (MT/MLT/MLS) FT, Days (7 on/ 7 off) Grand River Health | Rifle, CO At Grand River, we are ... Shift Differentials: $2-$4/hour for nights and weekends * Comprehensive Benefits: Medical, dental ...

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Showing results 1-20

Weekend Lab information

See Colorado salary details

$10

$26

$47

How much do weekend lab jobs pay per hour?

As of Sep 9, 2026, the average hourly pay for weekend lab in Colorado is $26.55, according to ZipRecruiter salary data. Most workers in this role earn between $20.24 and $29.33 per hour, depending on experience, location, and employer.

What is a Weekend Lab?

A Weekend Lab job typically refers to a laboratory technician or assistant position where the primary work schedule falls on weekends. Employees in this role are responsible for performing lab tests, managing samples, maintaining equipment, and recording data, often in hospitals, research facilities, or diagnostic labs. Weekend Lab staff play a critical part in ensuring continuous laboratory operations, especially when full-time weekday staff are unavailable. These positions may require technical skills, attention to detail, and the ability to work independently. Weekend Lab jobs are ideal for individuals seeking flexible work hours or supplemental income.

What are some unique challenges faced by professionals working in a Weekend Lab position?

Professionals in a Weekend Lab role often encounter challenges such as managing time-sensitive experiments with limited weekday support and adapting to a quieter, sometimes solitary work environment. Being responsible for ongoing research or diagnostic work during weekends requires strong organization and the ability to troubleshoot issues independently. Collaboration with weekday staff is essential, so clear documentation and effective communication are key to ensuring continuity and data integrity across shifts.

What are the key skills and qualifications needed to thrive as a Weekend Lab technician, and why are they important?

To thrive as a Weekend Lab Technician, you need a solid understanding of laboratory procedures, attention to detail, and at least an associate degree or certification in laboratory science. Familiarity with laboratory information systems (LIS), automated analyzers, and standard lab equipment is typically required. Strong problem-solving skills, effective communication, and the ability to work independently are crucial soft skills for this role. These competencies ensure accurate test results, efficient workflow, and reliable laboratory operations during weekend shifts.

What is the difference between Weekend Lab vs Medical Laboratory Technician?

AspectWeekend LabMedical Laboratory Technician
CredentialsTypically requires a certification or training specific to weekend shiftsRequires an associate degree in medical laboratory technology and certification
Work EnvironmentLaboratories operating on weekend schedules, often in hospitals or clinicsHospitals, clinics, or diagnostic labs during regular or weekend hours
Industry UsageUsed in healthcare settings needing weekend coverageStandard role in medical diagnostics and lab testing

Weekend Lab roles focus on providing laboratory services during weekends, often requiring specific certifications for weekend work. Medical Laboratory Technicians perform diagnostic tests in healthcare labs, usually with formal education and certification. While both work in lab environments, Weekend Lab positions are tailored for weekend shifts, whereas Medical Laboratory Technicians work throughout the week. Understanding these differences helps job seekers find roles aligned with their credentials and scheduling preferences.

What are the most commonly searched types of Lab jobs in Colorado?

The most popular types of Lab jobs in Colorado are:

What cities in Colorado are hiring for Weekend Lab jobs?

Cities in Colorado with the most Weekend Lab job openings:

Infographic showing various Weekend Lab job openings in Colorado as of August 2026, with employment types broken down into 1% As Needed, 69% Full Time, 24% Part Time, 5% Contract, and 1% Nights. Highlights an 92% Physical, 1% Hybrid, and 7% Remote job distribution, with an average salary of $55,222 per year, or $26.5 per hour.

Technologist: Medical Lab Scientist - Weekend Night Shift (Full-time)

Pagosa Springs, CO

Pagosa Springs Medical Center
Health Care and Social Assistance • 201 - 500 employees

$33.25 - $51.40/hr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 4 days ago


Job description

Medical Lab Scientist (MLS/MT) – Weekend Nights (Fri-Sun | 36 Hours per Week)

Department: Laboratory
Status: Full-Time | 0.9 FTE (36 hours/week)
Schedule: Friday – Sunday | 6:00 p.m. - 6:00 a.m.
FLSA Status: Non-Exempt
Reports To: Manager – Laboratory
Location: Pagosa Springs Medical Center – Pagosa Springs, Colorado


Position Highlight

Work three 12-hour night shifts and enjoy four days off each week—while practicing as a true laboratory generalist in a full-service rural hospital.


Position Summary

Pagosa Springs Medical Center (PSMC) is seeking a skilled and independent Medical Lab Scientist (MLS/MT) to join our Laboratory team on a weekend night shift schedule.

This role performs a wide range of technical and analytical laboratory procedures across multiple disciplines including hematology, chemistry, microbiology, blood bank, serology, urinalysis, coagulation, and phlebotomy. Responsibilities include performing routine and specialized testing, maintaining instrumentation, ensuring quality control, and delivering accurate and timely results to support patient care.

This position is ideal for experienced lab professionals who thrive in an autonomous environment and enjoy working as a generalist across multiple lab disciplines.


Schedule Highlights
  • Full-time equivalent (36 hours/week)
  • Weekend night shift: Friday – Sunday, 6:00 p.m. – 6:00 a.m.
  • 4 days off each week
  • Consistent, predictable schedule

Key ResponsibilitiesLaboratory Testing & Analysis
  • Perform routine and specialized laboratory testing across multiple disciplines
  • Analyze, evaluate, and verify test results for accuracy and reliability
  • Identify abnormal and critical values and follow proper reporting protocols
Phlebotomy & Specimen Handling
  • Perform phlebotomy and specimen collection as needed
  • Ensure proper specimen labeling, handling, and transport
  • Evaluate specimen integrity and follow rejection protocols
Quality Control & Compliance
  • Perform and document quality control procedures
  • Participate in proficiency testing and quality improvement activities
  • Maintain compliance with laboratory policies and regulatory standards
Instrumentation & Troubleshooting
  • Perform routine maintenance and troubleshooting of laboratory equipment
  • Identify and resolve equipment or testing issues
  • Maintain operational readiness of laboratory systems
Documentation & LIS
  • Accurately document results in the Laboratory Information System (LIS)
  • Enter, verify, and correct test results as needed
  • Maintain complete and accurate records
Team Collaboration
  • Communicate effectively with providers and clinical staff
  • Assist with training and support of laboratory personnel
  • Support overall laboratory workflow and operations
Education
  • Associate’s, Bachelor’s, Master’s, or Doctorate degree in Laboratory Sciences with completion of an approved internship program
Experience
  • Minimum five (5) years of experience as a Medical Lab Scientist / Technologist preferred
  • Generalist experience in a hospital setting strongly preferred
Licensure & Certifications
  • MLT (ASCP/AMT) or MT/MLS certification required (or ability to obtain within 2 years)
  • Current AHA BLS certification required
Skills
  • Strong analytical and problem-solving abilities
  • Ability to work independently, especially during night shifts
  • Attention to detail and commitment to accuracy
  • Ability to distinguish colors for test interpretation
  • Proficiency with laboratory systems and electronic health records

Work Environment
  • Hospital laboratory setting
  • Exposure to blood, bodily fluids, and hazardous materials
  • Fast-paced environment with frequent interruptions
  • Physical activity including standing, walking, and lifting

Compensation & Benefits
  • Base Compensation Range: $33.25 - $51.40 hourly, based on 0-22 years of relevant experience. "Relevant experience" means relevant to the employee's responsibilities set forth in the job description as determined by the HR Manager, CAO, applicable department manager/director and applicable senior leader. 
  • Shift Differential Pay: 
    • Night Shift Differential: Employees who work majority of hours between 6:30 p.m. and 7:00 a.m. receive a Night Shift Differential of an additional $5.00 per hour. 
  • Starting Work Bonus: This position is eligible for a starting work bonus of up to $5,000. Eligibility, amount, and payment terms are subject to Pagosa Springs Medical Center’s compensation policies and may vary based on position, experience, and employment status. Bonus payments, if applicable, are typically issued after the employee has met required employment and service criteria. 
  • Moving Expense Reimbursement: This position is eligible for a moving expense reimbursement of up to $3,000. Reimbursement is subject to Pagosa Springs Medical Center’s relocation policy and requires prior approval. Eligible expenses and reimbursement amounts may vary based on position and individual circumstances. Reimbursement is processed in accordance with established policy and applicable tax regulations. 
  • Benefits: Benefits include generous paid time off, separate sick leave, health, dental, vision, life and AD&D insurance, long-term disability and option for short-term disability, and retirement plan with employer contribution.  
  • Job Type: Full-time  
  • Shift Type: Weekend night shift: Friday – Sunday, 6:00 p.m. - 6:00 a.m.
  • Anticipated End Date for Posting: September 30, 2026. The deadline may close sooner due to an unanticipated business necessity, such as an incumbent vacating the role earlier than anticipated. You are encouraged to apply well in advance of the deadline.  

Why Join PSMC
  • 3-day workweek with full-time equivalent benefits
  • Opportunity to work as a true generalist across multiple lab disciplines
  • Strong team environment with supportive leadership
  • Meaningful work supporting rural healthcare

Pagosa Springs Medical Center is an Equal Opportunity Employer. All qualified applicants will be considered for employment, and we will not discriminate against any person on the basis of race, color, national origin, disability, age, sex, religion, creed, ancestry, sexual orientation, marital status, or any other characteristic protected by law. Offers of employment are contingent upon successful completion of a pre-employment health and drug screen and background check.Â