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Weekday Rn Jobs in California (NOW HIRING)

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Weekday Rn information

What is a weekday RN?

Weekday RNs are registered nurses who primarily work shifts scheduled during weekdays, typically Monday through Friday. Their responsibilities include assessing patient health, administering medications, coordinating care, and collaborating with physicians and other healthcare professionals. Weekday RNs are often employed in hospitals, clinics, doctors’ offices, and other healthcare settings where regular weekday coverage is needed. They may work standard business hours or rotating daytime shifts, depending on the employer. This schedule can offer more predictable hours compared to weekend or night shifts, making it appealing to many nurses.

What are some common challenges faced by weekday RNs, and how can these be managed effectively?

Weekday RNs often face challenges such as balancing a high patient load, coordinating care across multidisciplinary teams, and managing time-sensitive tasks within standard business hours. Effective communication, strong organizational skills, and proactive collaboration with physicians and allied health professionals can help manage these demands. Additionally, staying current with hospital protocols and leveraging electronic health record systems can streamline workflow and reduce stress.

What are the key skills and qualifications needed to thrive as a weekday RN, and why are they important?

To thrive as a Weekday RN, you need comprehensive nursing knowledge, clinical assessment abilities, and a current RN license, often supported by a nursing degree. Familiarity with electronic health record (EHR) systems, medication administration tools, and hospital protocols is essential. Strong communication, teamwork, and time-management skills help nurses coordinate patient care and adapt to changing situations. These skills ensure safe, efficient, and high-quality care during busy weekday shifts when patient volumes and collaboration demands are often at their peak.

What is the difference between Weekday Rn vs Weekend Rn?

AspectWeekday RnWeekend Rn
Work ScheduleTypically Monday to Friday, standard daytime hoursPrimarily weekends, often evening or night shifts
CertificationsRegistered Nurse (RN) license, possibly specific to hospital or clinicSame as Weekday Rn, with additional flexibility for weekend coverage
Work EnvironmentHospitals, clinics, outpatient facilitiesHospitals, urgent care, or clinics with weekend hours
Employer UsageHospitals, healthcare agencies, clinicsSame as Weekday Rn, but with weekend staffing needs

Weekday Rns work during regular weekday hours, while Weekend Rns provide care during weekends. Both roles require similar certifications and work in comparable healthcare settings, but their schedules differ to meet patient care needs outside typical hours.

What are the most commonly searched types of Rn jobs in California?

The most popular types of Rn jobs in California are:

What cities in California are hiring for Weekday Rn jobs?

Cities in California with the most Weekday Rn job openings:

Infographic showing various Weekday Rn job openings in California as of August 2026, with employment types broken down into 2% As Needed, 52% Full Time, 17% Part Time, and 29% Contract. Highlights an 99% Physical, and 1% Remote job distribution.

Weekend & Weekday Field Specialty Infusion Nurse - Per Diem

Simi Valley, CA • On-site

$50 - $55/hr

Per diem

Re-posted 4 days ago


Job description

Description:

Creating Waves of Compassion, Integrity, and Excellence 


At Yemaya Home Health LLC, we believe exceptional care begins with the nurse at the patient's side. Our mission is to provide compassionate, safe, and individualized care while allowing patients to receive specialized therapies in the comfort and familiarity of their own homes. 

Our Field Infusion Nurses are an essential part of that mission. We work collaboratively with patients, families, specialty pharmacies, providers, and members of the healthcare team to provide continuity of care throughout each patient's treatment journey. 

We are seeking experienced and dependable Registered Nurses who are confident in their clinical abilities, passionate about one-on-one patient care, and comfortable working independently in the field. 

Position Summary 

The Field Specialty Infusion Nurse (RN) provides direct nursing care to patients receiving prescribed infusion therapies in their homes or other approved settings. 

The RN is responsible for assessing the patient, establishing and maintaining appropriate vascular access, administering prescribed therapies, monitoring the patient's response to treatment, providing patient and caregiver education, and completing accurate clinical documentation. 

This is a per diem field position with a variable schedule based on patient census and clinical needs. There are no guaranteed or fixed weekly hours. 

Patient assignments may vary by location, treatment schedule, referral volume, and nurse availability. We are seeking nurses who value per diem work and are able to accommodate patient visits as assignments become available. 

Weekend availability is required, with additional weekday opportunities available based on patient needs and census. 

Essential Responsibilities 

The Field Specialty Infusion Nurse will: 

  • Provide safe, high-quality infusion therapy according to physician orders, pharmacy protocols, and the established plan of care. 
  • Perform comprehensive nursing assessments before, during, and following treatment. 
  • Demonstrate strong proficiency with peripheral IV insertion and vascular access management
  • Administer prescribed specialty therapies, which may include IVIG, biologics, IV antibiotics, hydration, and other specialty medications
  • Access and manage PICC lines, implanted ports, and other vascular access devices when within the nurse's demonstrated competency and assigned plan of care. 
  • Closely monitor patients for therapeutic response, adverse reactions, and changes in clinical condition. 
  • Recognize potential infusion reactions and initiate appropriate interventions according to established orders and emergency protocols. 
  • Educate patients and caregivers regarding prescribed therapy, medications, potential side effects, vascular access care, and treatment expectations. 
  • Maintain accurate, timely, and professional clinical documentation for each patient visit. 
  • Communicate significant changes in patient condition to the appropriate provider, pharmacy, and clinical team. 
  • Coordinate with patients, caregivers, pharmacies, physicians, and other members of the care team to support continuity of care. 
  • Properly handle, inspect, and manage infusion medications, supplies, pumps, and other equipment. 
  • Maintain patient confidentiality and comply with HIPAA requirements. 
  • Follow Yemaya Home Health LLC policies and procedures as well as applicable federal, state, professional, and clinical standards. 
  • Maintain required competencies, certifications, training, and continuing education. 
  • Demonstrate professionalism, accountability, compassion, and sound independent clinical judgment while representing Yemaya Home Health LLC in the field. 

Scheduling & Availability 

This is a per diem position and does not offer a set or guaranteed weekly schedule. 

Patient visits are assigned according to patient census, treatment needs, geographic location, and nurse availability

Candidates should understand that: 

  • Weekend availability is required. 
  • Weekday availability is strongly preferred. 
  • Patient visit times and durations may vary. 
  • Weekly hours may fluctuate depending on patient census. 
  • There are no guaranteed minimum weekly hours. 
  • Nurses may be offered additional assignments as patient census and coverage needs increase. 
  • Field nurses must be willing and able to travel to patients within their designated service area. 
  • Flexibility and dependability are essential to this position.
Requirements:

Job Requirements  

  • Active and unrestricted California Registered Nurse (RN) license
  • Current BLS/CPR certification
  • Strong proficiency and demonstrated competency with peripheral IV insertion
  • Hands-on IV therapy experience. 
  • Ability to perform patient assessments and recognize changes in clinical condition. 
  • Strong clinical documentation and communication skills. 
  • Ability to work independently and exercise appropriate clinical judgment in a home environment. 
  • Valid driver's license. 
  • Reliable transportation and current automobile insurance. 
  • Ability and willingness to travel throughout the assigned service area. 
  • Ability to meet all applicable onboarding, credentialing, competency, and compliance requirements. 
  • Weekend and Flexibilty scheduling availability. 

Preferred Qualifications 

We are especially interested in nurses with experience in one or more of the following areas: 

  • IVIG administration 
  • Specialty infusion therapy 
  • Biologic therapies 
  • IV antibiotics 
  • Hydration therapy 
  • Peripheral IV insertion 
  • PICC line management 
  • Implanted port access 
  • Infusion pumps 
  • Home infusion 
  • Infusion centers 
  • Oncology or hematology 
  • Acute care or other specialty nursing environments 

Previous home or specialty infusion experience is strongly preferred

The Nurse We're Looking For 

Clinical skills are important, but so is the way our nurses care for patients. 

We are looking for nurses who are compassionate, dependable, clinically confident, adaptable, and comfortable working independently. Our nurses enter patients' homes during vulnerable moments, and we expect every patient interaction to reflect professionalism, respect, integrity, and exceptional care. 

The ideal candidate understands that field infusion nursing requires more than administering medication—it requires building trust, educating patients and families, recognizing changes in condition, communicating effectively with the care team, and ensuring patients feel safe and supported throughout their treatment. 

Why Yemaya Home Health LLC? 

At Yemaya Home Health LLC, our commitment is reflected in the care we provide and the professionals who represent us. 

Our nurses have the opportunity to: 

  • Provide meaningful one-on-one patient care
  • Utilize and strengthen specialized infusion nursing skills. 
  • Work independently while remaining connected to a collaborative clinical team. 
  • Care for patients receiving a variety of specialty therapies. 
  • Maintain the flexibility of a per diem field nursing schedule. 
  • Accept additional patient assignments as opportunities become available. 
  • Make a direct difference in a patient's ability to safely receive treatment at home. 

Creating Waves of Compassion, Integrity, and Excellence isn't simply our motto—it represents the standard of care we strive to provide with every patient, every visit, and every interaction.
 

How to Apply 

Please submit a current resume that clearly outlines your infusion nursing experience and IV skills, including experience with IVIG, biologics, specialty medications, peripheral IV insertion, PICC lines, implanted ports, and/or other infusion therapies. 

Qualified candidates will be contacted to discuss their clinical experience, availability, service area, and the next steps in our interview process.