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Vertex Program Manager Jobs (NOW HIRING)

Vertex Pharmaceuticals

Research Scientist

Boston, MA · On-site

$104K - $156K/yr

The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be ... manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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$38.5K

$107.5K

$157K

How much do vertex program manager jobs pay per year?

As of Jun 3, 2026, the average yearly pay for vertex program manager in the United States is $107,460.00, according to ZipRecruiter salary data. Most workers in this role earn between $79,500.00 and $132,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Vertex Program Manager, and why are they important?

To thrive as a Vertex Program Manager, you need strong project management skills, industry knowledge (such as biotech or pharmaceuticals), and a relevant bachelor's or master's degree. Familiarity with project management software (like MS Project or Smartsheet), regulatory compliance systems, and possibly PMP certification is often required. Exceptional leadership, communication, and problem-solving skills help drive cross-functional teams and stakeholder engagement. These competencies ensure projects are delivered on time, within scope, and in compliance with industry standards, which is crucial for organizational success.

How does a Vertex Program Manager typically collaborate with cross-functional teams during project execution?

As a Vertex Program Manager, you will frequently coordinate with engineering, product, and client-facing teams to ensure project milestones are met on schedule. Effective collaboration involves facilitating regular update meetings, aligning on priorities, and swiftly addressing any roadblocks. You’ll act as a central point of communication, ensuring all stakeholders are informed and working towards a unified goal. This role requires strong organizational and interpersonal skills to balance competing demands and maintain project momentum.

What are Vertex Program Managers?

Vertex Program Managers are professionals responsible for overseeing and coordinating programs or projects related to Vertex, which can refer to Google Cloud's Vertex AI platform or, in some contexts, the biopharmaceutical company Vertex Pharmaceuticals. In the context of Google Cloud, Vertex Program Managers facilitate the planning, execution, and delivery of AI and machine learning projects, ensuring they align with organizational goals and client needs. Their responsibilities include collaborating with cross-functional teams, managing timelines and resources, and ensuring successful project implementation. Strong organizational, communication, and technical skills are essential for this role.

What is the difference between Vertex Program Manager vs Vertex Project Coordinator?

AspectVertex Program ManagerVertex Project Coordinator
CredentialsTypically requires a bachelor's degree in business, management, or related field; PMP or similar certifications are commonUsually requires a bachelor's degree; certifications are less common but beneficial
Work EnvironmentLeads multiple projects, manages teams, and oversees strategic initiatives within the companySupports project teams, handles scheduling, and assists in project execution
Employer & Industry UsageUsed across industries like technology, finance, and consulting; common in large organizationsCommon in project-driven industries such as construction, IT, and manufacturing

The Vertex Program Manager focuses on strategic oversight and leadership of multiple projects, requiring higher-level management skills and certifications. In contrast, the Vertex Project Coordinator provides support in project execution and coordination, often serving as a team member. Both roles are essential but differ in scope and responsibility within organizations.

Infographic showing various Vertex Program Manager job openings in the United States as of May 2026, with employment types broken down into 6% Internship, 46% As Needed, 6% Full Time, 12% Temporary, 24% Contract, and 6% Nights. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $107,460 per year, or $51.7 per hour.
Clinical Development Senior Medical Director-Neurology

Clinical Development Senior Medical Director-Neurology

Vertex Pharmaceuticals

Boston, MA • On-site

$280.60K - $420.80K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 17 days ago

Job description

Job Description
General Summary:
The Senior Medical Director will define the clinical development strategy of an asset, work with cross-functional multidisciplinary teams to define overall asset strategy as well as clinical trials strategy, design and execution, and may serve as the Medical Lead for clinical trials that will be conducted with these compounds.
Key Duties and Responsibilities:
  • Defines a clinical development strategy and prepare the clinical development plans, in conjunction with other relevant functional areas
  • Participates in the development of study protocols, statistical analysis plans, investigator's brochures, and other key study documents in conjunction with other line functions and with minimal guidance
  • Leads the Project Team, and works with cross-functional team members to define a project strategy and ensure execution against approved strategy
  • Participates in the preparation of regulatory documents in support of regulatory submissions, including clinical section of INDs and CTAs, safety reports, responses to regulatory authorities, clinical study reports, and other documents as appropriate
  • Interfaces with regulatory authorities as appropriate
  • Monitors and/or oversees medical monitoring of clinical studies
  • Participates in business development and strategic planning activities
  • Acts as liaison between clinical development and other internal groups at Vertex for assigned studies
  • Provides medical and development leadership for cross-functional teams
  • Serves on cross-functional study teams for assigned trials, working with other team members to achieve efficient, high-quality study execution, and data analysis
  • Represents Vertex to outside medical personal in the development of clinical protocols and study conduct

Knowledge and Skills:
  • Global clinical research experience, and experience interacting with regulatory authorities is highly desired
  • Ability to work collaboratively in a fast-paced, team-based matrix environment
  • Ability to work independently to resolve challenges
  • Enterprise-wide thinking and ability to work in ambiguity
  • Ability to ensure the completeness of team work
  • Excellent oral and written communication skills
  • Board certification/eligibility in a specialty is highly desired

Education and Experience:
  • MD, DO or equivalent ex-US medical degree
  • Board certification/eligibility in a specialty is highly desired
  • Typically requires 12 years Pharmaceutical/Biotech industry experience, including time managing clinical trials and clinical development programs, or the equivalent combination of education and experience

#LI-JM1
Pay Range:
$280,600 - $420,800
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site Eligible
Flex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Hybrid
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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