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Upstream Jobs (NOW HIRING)

Pinnaql

Validation Engineer - Upstream

Juana Diaz, PR · On-site

Validation Engineer - Upstream Description: We are seeking a Validation Engineer with experience in upstream equipment to join our team. The Validation Engineer will be responsible for validating ...

Chord Energy

Senior Upstream Accountant

Houston, TX · On-site

$70K - $88K/yr

Chord Energy is seeking an experienced and results-driven Senior Upstream Accountant to join our dynamic Accounting team in supporting our growing upstream oil and gas assets. The successful ...

SIGNOBIO INC

Upstream Associate

Houston, TX · On-site

As an Associate, Upstream, you'll assist in recombinant protein and antibody expression using mammalian cell cultures, while also supporting QC testing to evaluate product quality. You'll work ...

UCB

Upstream Biomanufacturing Process Expert

Atlanta, GA · On-site

We are looking for an Upstream Biomanufacturing Process Expert who is collaborative, detail-oriented, and innovative to join us in our Internal Manufacturing team , based at our UCB campus located in ...

Factset

Manager, Upstream Oil & Gas

Lakewood, CO

Your Team's Impact You will lead a team of upstream oil and gas subject matter experts, data scientists, and research analysts based in the United States and India. Your team is responsible for ...

UCB

Upstream Biomanufacturing Process Expert

Atlanta, GA · On-site

$164K/yr

We are looking for an Upstream Biomanufacturing Process Expert who is collaborative, detail-oriented, and innovative to join us in our Internal Manufacturing team , based at our UCB campus located in ...

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Showing results 21-40

All JobsUpstream Jobs

Upstream information

See salary details

$59K

$90.8K

$155.5K

How much do upstream jobs pay per year?

As of Aug 11, 2026, the average yearly pay for upstream in the United States is $90,768.00, according to ZipRecruiter salary data. Most workers in this role earn between $77,500.00 and $89,500.00 per year, depending on experience, location, and employer.

What are some common challenges faced by professionals working in upstream oil and gas operations?

Professionals in upstream oil and gas often contend with challenging field conditions, complex regulatory requirements, and the need to balance operational efficiency with safety and environmental standards. The role frequently involves working in remote locations, collaborating with multidisciplinary teams, and adapting to rapidly changing technologies. Navigating project timelines, resource constraints, and evolving industry regulations can also present significant challenges, but these aspects offer valuable experience and opportunities for skill development and career advancement.

What are upstream jobs in the oil and gas industry?

Upstream jobs in the oil and gas industry refer to positions involved in the exploration and production of oil and natural gas. This includes locating oil and gas fields, drilling wells, and extracting resources from beneath the earth's surface. Common upstream roles include geologists, drilling engineers, and production operators. These jobs are crucial in the early stages of the energy supply chain and often involve working in the field or on offshore rigs.

What is the difference between Upstream vs Downstream?

AspectUpstreamDownstream
Primary FocusExploration, drilling, and production of oil and gasRefining, distribution, and marketing of oil and gas products
Work EnvironmentOil fields, drilling sites, exploration areasRefineries, distribution centers, retail outlets
Required CredentialsGeology, petroleum engineering, certifications in drilling and safetyChemical engineering, marketing, logistics certifications
Industry UsageExploration and production companiesRefining companies, oil and gas marketers

Upstream involves the exploration and extraction of oil and gas, focusing on drilling and production. Downstream covers refining, distribution, and selling petroleum products. Both roles are essential in the oil industry but differ in their focus, work environment, and required skills.

What are the key skills and qualifications needed to thrive as an upstream oil and gas engineer, and why are they important?

To thrive as an Upstream Oil & Gas Engineer, you need a solid background in petroleum engineering, geology, or a related field, often supported by a relevant degree. Familiarity with reservoir simulation software, drilling technologies, and industry safety standards is essential. Strong analytical thinking, teamwork, and effective communication distinguish top performers in this role. These skills ensure efficient resource extraction, operational safety, and collaboration in complex exploration and production environments.
More about Upstream jobs
What cities are hiring for Upstream jobs? Cities with the most Upstream job openings:
What states have the most Upstream jobs? States with the most job openings for Upstream jobs include:
What job categories do people searching Upstream jobs look for? The top searched job categories for Upstream jobs are:
Upstream jobs near you
Infographic showing various Upstream job openings in the United States as of August 2026, with employment types broken down into 50% Full Time, and 50% Contract. Highlights an 100% In-person job distribution, with an average salary of $90,768 per year, or $43.6 per hour.

Upstream Process Development

Integrated Resources INC

South Plainfield, NJ

Full-time

Re-posted 21 days ago

Job description

Company Description

A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing.

Job Description

Upstream Process Development Scientist

Experience in development of mammalian cell culture processes for the production of recombinant proteins is a plus. Knowledge of protein chemistry and purification techniques and purification process development experience is preferred. Basic knowledge of cGMP policies and procedures. Basic knowledge of regulatory requirements of the pharmaceutical / biotechnology industry.


Key Responsibilities:

Design and execute experiments for production of proteins using microbial fermentation processes.      Design, analyze and interpret lab experiments, purification data, in-process trends, productivity and quality attributes to support upstream process development.

Lead efforts to evaluate different fermentation media, feeds, and feeding strategies to improve product yield and quality including proper folding of protein

Scale up process developed at research stage to manufacture adequate amounts of protein to support clinical trials

Author technical documentation including process validation protocols and reports.

Evaluate process robustness, investigate causes of process variances, and take steps to maximize process reproducibility.

Qualifications

Basic qualifications: Ph.D., MS or BS in Chemical/Biochemical Engineering or related Biological Sciences is required. For a candidate with a Ph.D. >3 yrs. of industrial experience; candidate with an MS >5 yrs. industrial experience and for a candidate with a BS, >7 years of industrial experience in developing upstream microbial fermentation processes for the production of bio-pharmaceuticals is required. Specific experience in development of microbial expression processes for soluble protein production is preferred.

Additional Information



 

Integrated Resources logo

About Integrated Resources

Sourced by ZipRecruiter

Integrated Resources Inc (IRI), based in Edison, NJ, US, is an esteemed player in the staffing solutions industry with a credible presence on their official website irionline.com. Notably, IRI provides a range of professional staffing services including contract, contract-to-hire, and direct hire solutions to a wide spectrum of industries such as healthcare, life sciences, manufacturing, financial, insurance, and others. Since its inception, IRI has been committed to delivering top-talent and optimum solutions to meet its clients' diverse needs.

Industry

Recruiting and staffing services

Company size

51 - 200 Employees

Headquarters location

Edison, NJ, US

Year founded

1996

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